Results 111 to 120 of about 167,750,294 (239)

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Grace, Idaho, 1923: Built by Quince R. Pack

, 1923
Black and white photograph by Fred Pack during a visit to his brother, Quince R. Pack, at Grace, Idaho, in July of 1923.
Pack, Frederick J. (Frederick James), 1875-1938
core  

Front–of–pack nutrition labeling: ultra-processed foods are the elephant in the room

The Lancet Regional Health. Americas, 2023
Mélissa Mialon
doaj   +1 more source

Design Rules for Quantitative Control of Intragrain Planar Defects in Halide Perovskites

Advanced Science, EarlyView.
Dose‐budgeted electron microscopy reveals the design rules governing intragrain planar defects in halide perovskites: {112}t ferroelastic twins proliferate with increasing tetragonality and grain size, whereas {111}c twins and stacking faults emerge as the lattice approaches cubic symmetry.
Byeongjun Gil, So Jeong Park, Jin Young Kim, Miyoung Kim   +3 more
wiley   +1 more source

Grace, Idaho, 1923: Built by Q. R. Pack

, 1923
Black and white photograph by Fred Pack during a visit to his brother, Quince R. Pack, at Grace, Idaho, in July of 1923.
Pack, Frederick J. (Frederick James), 1875-1938
core  

Association between the diagnosis of diet-related non-communicable diseases and the use of nutritional labeling among Mexican, Mexican American, and non-Mexican American adults: a cross-sectional study from the International Food Policy Study 2021–2022

BMC Public Health
Background Diet-related non-communicable diseases (NCDs) are major global health concerns. Front-of-package warning labels (WLs) and nutrition facts labels (NFLs) aim to promote healthier food choices, yet their use among individuals with NCDs and across
Isabel García-Perfecto, Alejandra Contreras-Manzano, Kathia Larissa Quevedo, Christine M. White, Lana Vanderlee, Rachel E. Davis, Cecilia I. Oviedo-Solís, James F. Thrasher, Simón Barquera, David Hammond, Claudia Nieto, Dai Fang, Alejandra Jáuregui   +12 more
doaj   +1 more source

Prevalence of High Fat Sugar Salt Products, Labeling Characteristics, and Categories of Foods Sold within In-Store Restricted Areas: A Survey in 3 UK Supermarkets after the 2022 Implementation of the Food (Promotion and Placement) Regulations

Current Developments in Nutrition
Background: Regulations restricting the promotion of some less-healthy products high in fat, sugar, or salt (HFSS) within “restricted areas” (RAs) of supermarkets came into force in October 2022 in England.
Ella Hurst, Sally G Moore, Lewis W Wallis   +2 more
doaj   +1 more source

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

Advanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang, Meng Chen, Guanchen Li, Ruifeng Liu, Yingxin Wang, Ziran Zhao   +5 more
wiley   +1 more source