Results 91 to 100 of about 92,917 (264)

Divergent longitudinal propagation of white matter degradation in logopenic and semantic variants of primary progressive aphasia [PDF]

, 2015
Background: Clinico-pathological distinction of primary progressive aphasia (PPA) can be challenging at clinic presentation. In particular, cross-sectional neuroimaging signatures across the logopenic (lvPPA) and semantic (svPPA) variants are difficult ...
Agosta, Bach, Brambati, Chare, Deramecourt, Fletcher, Galantucci, Gorno-Tempini, Gorno-Tempini, Heim, Hickok, Keihaninejad, Lam, Mackenzie, Mahoney, Mesulam, Mesulam, Mioshi, Mioshi, Nichols, Powers, Rohrer, Rohrer, Saur, Savage, Smith, Smith, Smith, Varentsova, Wicklund, Zhang   +30 more
core   +1 more source

The We‐Relationship as a Key to Addressing Dementia‐Related Ambiguous Loss

Journal of Applied Philosophy, EarlyView.
ABSTRACT Pauline Boss describes the challenges faced by people caring for family members with dementia in terms of ambiguous loss – a condition in which the physical presence of the person with dementia coexists with their psychological absence. This article proposes the concept of we‐relationship as a key to addressing dementia‐related ambiguous loss.
Takuya Niikawa, Xue Li
wiley   +1 more source

Behavioral variant frontotemporal dementia in patients with previous severe mental illness: a systematic and critical review

Arquivos de Neuro-Psiquiatria
Objectives: To explore the relationship between severe/serious mental illness (SMI) and the behavioral variant of frontotemporal dementia (bvFTD), as the patterns of symptoms and cognitive performance that characterize both disorders share similarities.
Leandro Boson Gambogi, Henrique Cerqueira Guimarães, Leonardo Cruz De Souza, Paulo Caramelli   +3 more
doaj   +1 more source

Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene. [PDF]

, 2017
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two apparently distinct neurodegenerative diseases, the former characterized by selective loss of motor neurons in the brain and spinal cord and the latter characterized by ...
Pasinelli, Piera, Trotti, Davide, Wen, Xinmei, Westergard, Thomas   +3 more
core   +2 more sources

The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion‐Tensor‐Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca, Gianmauro Palombelli, Nicola Vanacore, Rossella Canese   +3 more
wiley   +1 more source

Early affective changes and increased connectivity in preclinical Alzheimer's disease. [PDF]

, 2018
IntroductionAffective changes precede cognitive decline in mild Alzheimer's disease and may relate to increased connectivity in a "salience network" attuned to emotionally significant stimuli.
Bilgel, Murat, Brown, Jesse A, Fredericks, Carolyn A, Hua, Alice Y, Resnick, Susan M, Seeley, William W, Sturm, Virginia E, Wong, Dean F   +7 more
core   +1 more source

Preclinical and Prodromal Frontotemporal Dementia: Challenges and Opportunities

International Journal of Translational Medicine
Frontotemporal lobar degeneration (FTLD) represents a heterogeneous group of neurodegenerative disorders with overlapping clinical, pathological, and genetic characteristics.
Federica Palacino, Paolo Manganotti, Alberto Benussi   +2 more
doaj   +1 more source

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner, Franziska Eberhardt, Manuela Kofler, Andreas Eigentler, Atbin Djamshidian, Florian Krismer, Anton Hittmair, Heinz Zoller, Valentina Ellinger, Beatrice Heim, Klaus Seppi   +10 more
wiley   +1 more source

Frontotemporal dementia with severe thalamic involvement : a clinical and neuropathological study

Arquivos de Neuro-Psiquiatria, 2003
Frontotemporal dementia (FTD) is the third-leading cause of cortical dementia after Alzheimer's disease and Lewy body dementia, and is characterized by a dementia where behavioral disturbances are prominent and appear early in the course of the disease ...
Radanovic Márcia, Rosemberg Sérgio, Adas Rogério, Miranda Stênio C., Caramelli Paulo, Caixeta Leonardo, Nitrini Ricardo   +6 more
doaj  

Agraphia in Bulbar-Onset Amyotrophic Lateral Sclerosis: Not Merely a Consequence of Dementia or Aphasia

Behavioural Neurology, 2008
The clinical significance and characteristics of writing errors in bulbar-onset amyotrophic lateral sclerosis (ALS) are not clear. We retrospectively investigated writing samples in 19 patients with bulbar-onset ALS without preceding extra-motor symptoms.
Hiroo Ichikawa, Nobuyoshi Takahashi, Soutaro Hieda, Hideki Ohno, Mitsuru Kawamura   +4 more
doaj   +1 more source