Results 111 to 120 of about 329,751 (255)

Negative neurofilament light and tau immunostaining in frontotemporal dementia

, 2004
We investigated the immunohistochemical stainability of phosphorylated tau and the light (NFL), intermediate (NFM), and heavy (NFH) neurofilament proteins in postmortem brain tissue from 8 patients with frontotemporal dementia (FTD), for comparison with ...
Englund, Elisabet,, Sjogren, M, Lund University.   +2 more
core   +2 more sources

Preclinical and Prodromal Frontotemporal Dementia: Challenges and Opportunities

International Journal of Translational Medicine
Frontotemporal lobar degeneration (FTLD) represents a heterogeneous group of neurodegenerative disorders with overlapping clinical, pathological, and genetic characteristics.
Federica Palacino, Paolo Manganotti, Alberto Benussi   +2 more
doaj   +1 more source

Fluid Intelligence and Executive Dysfunction in Progressive Supranuclear Palsy

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Fluid intelligence (g) contributes to executive‐task performance, but its role in progressive supranuclear palsy (PSP) remains unclear. Objectives To examine whether executive deficits in PSP are explained by reductions in g. Methods Thirty‐five PSP patients, 39 Parkinson's disease (PD) patients and 18 healthy controls underwent ...
Federico Castano, Maria Roca, John Duncan, Blas Couto   +3 more
wiley   +1 more source

Improving care home design for people with dementia [PDF]

, 2010
With more people with dementia living in care homes in the UK than ever before, there is growing recognition that the design of such internal and external spaces should meet dementia friendly principles.
Innes, Anthea, Dincarslan, Ozlem, Fiona Kelly, Ozlem Dincarslan, Kelly, Fiona, Anthea Innes, Dincarslan, O.   +6 more
core   +1 more source

Frontotemporal dementia with severe thalamic involvement : a clinical and neuropathological study

Arquivos de Neuro-Psiquiatria, 2003
Frontotemporal dementia (FTD) is the third-leading cause of cortical dementia after Alzheimer's disease and Lewy body dementia, and is characterized by a dementia where behavioral disturbances are prominent and appear early in the course of the disease ...
Radanovic Márcia, Rosemberg Sérgio, Adas Rogério, Miranda Stênio C., Caramelli Paulo, Caixeta Leonardo, Nitrini Ricardo   +6 more
doaj  

From Uncertainty to Pathogenicity: Resolving a CSF1R Variant of Uncertain Significance Using Long‐Read Transcriptomics

Movement Disorders, EarlyView.
Abstract Background CSF1R‐related disorder (CSF1R‐RD) is a severe autosomal dominant leukoencephalopathy characterized by progressive cognitive, neuropsychiatric, and motor decline. Although genetic testing is widely available, numerous likely pathogenic variants in CSF1R frequently remain classified as variants of uncertain significance (VUS ...
Charles Wade, Kylie Montgomery, Gabriela E. Jones, Peter Sellars, Akram A. Hosseini, Simon Paine, Henry Houlden, Mina Ryten, David S. Lynch   +8 more
wiley   +1 more source

SPEECH AND LANGUAGE ABILITIES OF PERSONS WITH FRONTOTEMPORAL DEMENTIA [PDF]

, 2021
The review outlines the importance of understanding speech and language difficulties that occur among the first symptoms of frontotemporal dementia, as well as the role of speech therapists in the management of people with frontotemporal dementia ...
Banović, Silva, Sinanović, Osman
core  

Behavioral variant frontotemporal dementia in patients with previous severe mental illness: a systematic and critical review

Arquivos de Neuro-Psiquiatria
Objectives: To explore the relationship between severe/serious mental illness (SMI) and the behavioral variant of frontotemporal dementia (bvFTD), as the patterns of symptoms and cognitive performance that characterize both disorders share similarities.
Leandro Boson Gambogi, Henrique Cerqueira Guimarães, Leonardo Cruz De Souza, Paulo Caramelli   +3 more
doaj   +1 more source

Lewy Body Disease Across Aging: Clinical and Neuropathological Correlates in a Population Brain Bank

Movement Disorders, EarlyView.
Abstract Background Lewy body disease (LBD) is defined by neuronal α‐synuclein pathology, but how Braak‐staged LBD relates to mixed neuropathology and clinical manifestations within a single population‐based cohort remains incompletely characterized. This is especially relevant in cohorts enriched for younger individuals, which may better inform real ...
Vitor Ribeiro Paes, Felipe Luiz Pereira, Caroline Matos Silva, Filipe Oto Cunha de Moraes, Inês Liguori Padrão, Alberto Fernando Oliveira Justo, Roberta Diehl Rodriguez, Michel Satya Naslavsky, Renata Elaine Paraizo Leite, Carlos Augusto Gonçalves Pasqualucci, Mayana Zatz, Eduardo Ferriolli, Claudia Kimie Suemoto, Lea Tenenholz Grinberg   +13 more
wiley   +1 more source

Neuropsychological Evaluation of the Frontotemporal Dementia

, 2016
Diagnosis of Frontotemporal dementia (FTD) requires -besides brain imagining- a careful evaluation of diverse aspects including genetic and neuropathological, behavioural problems and cognitive processes.
Martínez Cuitiño Carricaburo, María Macarena, Torralva, Teresa, Manes, Facundo Francisco   +2 more
core   +1 more source