Results 121 to 130 of about 315,827 (302)

α‐Synuclein strain homogeneity in multiple system atrophy subtypes

Brain Pathology, EarlyView.
Two different subtypes of multiple system atrophy are recognized: MSA‐C and MSA‐P. In this manuscript, Lau et al. investigate whether MSA‐C and MSA‐P are caused by different strains of α‐synuclein aggregates. By performing conformational fingerprinting experiments as well as in vitro and in vivo seeding assays, their findings suggest that both MSA‐C ...
Heather H. C. Lau, Nicholas R. G. Silver, Surabhi Mehra, Raphaella W. L. So, Le yao Li, Alison Mao, Erica Stuart, Cian Schmitt‐Ulms, Bradley T. Hyman, Martin Ingelsson, Joel C. Watts   +10 more
wiley   +1 more source

Neuropsychological Evaluation of the Frontotemporal Dementia

, 2016
Diagnosis of Frontotemporal dementia (FTD) requires -besides brain imagining- a careful evaluation of diverse aspects including genetic and neuropathological, behavioural problems and cognitive processes.
Martínez Cuitiño Carricaburo, María Macarena, Torralva, Teresa, Manes, Facundo Francisco   +2 more
core   +1 more source

An Ecological and Processual Understanding of Family Resilience in Dementia: A Qualitative Meta‐Synthesis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore how family resilience emerges and unfolds in dementia. Design Qualitative meta‐synthesis using thematic synthesis. Data Sources PubMed, CINAHL, Web of Science, PsycINFO were searched from inception through August 26, 2025. Methods Studies examining family‐level resilience, adaptation or coping in home‐based dementia care using ...
Yoosun Yang, Jun‐Ah Song
wiley   +1 more source

Effects of the WeCareAdvisor Web App on Behavioral Symptoms and Caregiver Outcomes: A Randomized Trial

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Nonpharmacological strategies are first‐line treatments for behavioral symptoms, the most distressful aspect of dementia care. Few caregivers have knowledge of or access to effective strategies. We tested the effects of WeCareAdvisor, a web app to help caregivers problem‐solve and identify nonpharmacological strategies to manage ...
Laura N. Gitlin, Leslie A. McClure, Melinda J. Webster, Constantine Lyketsos, Helen C. Kales   +4 more
wiley   +1 more source

Negative neurofilament light and tau immunostaining in frontotemporal dementia

, 2004
We investigated the immunohistochemical stainability of phosphorylated tau and the light (NFL), intermediate (NFM), and heavy (NFH) neurofilament proteins in postmortem brain tissue from 8 patients with frontotemporal dementia (FTD), for comparison with ...
Englund, Elisabet,, Sjogren, M, Lund University.   +2 more
core   +1 more source

Mini social cognition and emotional assessment: Diagnostic performance and neural correlates in behavioural‐variant frontotemporal dementia

Journal of Neuropsychology, EarlyView.
Abstract We aimed at validating the Mini Social Cognition and Emotional Assessment (Mini‐SEA) in a German cohort of mildly impaired behavioural‐variant frontotemporal dementia (bvFTD) patients and healthy controls. The Mini‐SEA comprises the Facial Emotion Recognition Test (FERT) and the Faux Pas Test (FPT) measuring Theory of Mind (ToM) abilities in ...
Cem Doğdu, Neeraj Upadhyay, Ingo Frommann, Luca Kleineidam, Andreas Johnen, Melina Stark, Sandra Roeske, Annika Spottke, Anna Gamez, Gabor C. Petzold, Louise Droste zu Senden, Julian Hellmann‐Regen, Stefan Hetzer, Klaus Fliessbach, Carolin Miklitz, Emrah Düzel, Falk Lüsebrink, Wenzel Glanz, Stefan Teipel, Ingo Kilimann, Josef Priller, Eike Jakob Spruth, Johannes Prudlo, David Mengel, Klaus Scheffler, Matthis Synofzik, Anja Schneider, Michael Wagner   +27 more
wiley   +1 more source

Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated with the pathological variant c.2013T>G in the MAPT gene

Вавиловский журнал генетики и селекции
Frontotemporal dementia with parkinsonism-17 is a neurodegenerative disease characterised by pathological aggregation of the tau protein with the formation of neurofibrillary tangles and subsequent neuronal death.
E. V. Grigor’eva, A. A. Malakhova, E. S. Yarkova, J. M. Minina, Y. V. Vyatkin, J. A. Nadtochy, E. A. Khabarova, J. A. Rzaev, S. P. Medvedev, S. M. Zakian   +9 more
doaj   +1 more source

Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia : GENFI results

: INTRODUCTION Effective longitudinal biomarkers that track disease progression are needed to characterize the presymptomatic phase of genetic frontotemporal dementia (FTD).
Petr, Jan, Butler, Chris, Masellis, Mario, Rogaeva, Ekaterina, Graff, Caroline, Jiskoot, Lize C., Bocchetta, Martina, Bouzigues, Arabella, Seelaar, Harro, Santana, Isabel, Tartaglia, Maria Carmela, Russell, Lucy L., Laforce, Robert, Synofzik, Matthis, Mitchell, Sara B., Galimberti, Daniela, Freedman, Morris, Genetic Frontotemporal Dementia Initiative (GENFI), Moreno, Fermin, Ducharme, Simon, Sorbi, Sandro, Finger, Elizabeth, Gerhard, Alex, Black, Sandra E., Luciw, Nicholas, Levin, Johannes, van Swieten, John C, Mirza, Saira S., Rowe, James B., de Mendon\ue7a, Alexandre, Otto, Markus, Cash, David, Pasternak, Maurice, Tiraboschi, Pietro, MacIntosh, Bradley J., Sanchez-Valle, Raquel, Tang-Wai, David, Rohrer, Jonathan D., Bruffaerts, Rose, Borroni, Barbara, Strafella, Antonio P., Thomas, David, Mutsaerts, Henri J.M.M., Vandenberghe, Rik   +43 more
core  

Exploring Theory of Mind abilities in patients with probable idiopathic normal pressure hydrocephalus

Journal of Neuropsychology, EarlyView.
Abstract This study investigated Theory of Mind (ToM) deficits in patients with suspected idiopathic normal pressure hydrocephalus (iNPH), a condition affecting motor, cognitive and autonomic functions. Given the overlap between ToM‐related neural networks and those affected in iNPH, we examined whether ToM impairments are a feature of the disease ...
Akrivi Vatsi, George Stranjalis, Stylianos Gkatzonis, Christos Koutsarnakis, Eleftherios Neromyliotis, Aristotelis Kalyvas, Ion N. Beratis, Evangelos Drosos, Spyridon Komaitis, Evangelia Liouta   +9 more
wiley   +1 more source

Frontotemporal dementia [PDF]

Continuum, 2007
Indre Viskontas, Bruce Miller
openaire   +1 more source