Results 121 to 130 of about 50,646 (233)

Peripheral immune profiling in frontotemporal dementia. [PDF]

Brain Commun
Gamez N, Eid AM, Pascual B, Li D, Wang Y, Masdeu JC, Appel SH, Faridar A.   +7 more
europepmc   +1 more source

Cross‐ancestry polygenic risk scores enhance Alzheimer's disease risk prediction in multiethnic cohorts

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Genome‐wide association studies (GWAS) have identified 80+ genetic loci associated with Alzheimer's disease (AD), enabling the development of polygenic risk scores (PRS). However, the predictive accuracy of PRS in diverse populations remains low.
Meri Okorie, Caroline Jonson, Alexis P. Oddi, Patricia A. Castruita, Brian Fulton‐Howard, Kristine Yaffe, Jennifer S. Yokoyama, Chinedu Udeh‐Momoh, Shea J. Andrews, for the Alzheimer's Disease Sequencing Project and the Healthy Aging Brain Study—Health Disparities   +9 more
wiley   +1 more source

Temporal order of clinical, imaging, and biomarker changes in frontotemporal lobar degeneration–associated syndromes

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract BACKGROUND The temporal sequence of clinical, imaging, and biological changes in sporadic frontotemporal lobar degeneration (FTLD)–associated syndromes remains poorly characterized, and a comprehensive biomarker cascade model is lacking. METHODS We developed a data‐driven biomarker cascade model in 489 patients across the FTLD spectrum (211 ...
Alberto Benussi, Valeria Bracca, Enrico Premi, Valentina Cantoni, Federica Palacino, Aurora Saccavini, Maria Sofia Cotelli, Giuliano Binetti, Rosa Manenti, Antonella Alberici, Roberto Gasparotti, Nicholas J Ashton, Henrik Zetterberg, Kaj Blennow, Roberta Ghidoni, Barbara Borroni   +15 more
wiley   +1 more source

Alzheimer's Protection by PLCγ2 Compacts Plaques, Redistributes Microglia, and Protects Synapses in AppNL‐G‐F Mice

Glia, Volume 74, Issue 8, August 2026.
The Alzheimer's disease protective PLCG2 P522R variant protects against amyloid‐induced synapse loss independently of amyloid load, promotes increased plaque compaction, and is associated with enhanced microglial engagement with diffuse amyloid. ABSTRACT The Alzheimer's disease protective P522R PLCG2 coding variant (rs72824905) is downstream of TREM2 ...
Ryan J. Bevan, Emily Maguire, Eilish Mackinnon, Elisa Salis, Thomas Phillips, Elena Simonazzi, Marieta Vassileva, Nicholas D. Allen, Julie Williams, Philip R. Taylor   +9 more
wiley   +1 more source

Mobile Health Interventions to Support Patients With Dementia During the COVID‐19 Pandemic: A Systematic Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims During the COVID‐19 pandemic, mobile health (mHealth) utilization increased, especially among specific groups such as patients with dementia (PwD). This systematic review aimed to assess mHealth interventions among PwD during the COVID‐19 pandemic. Methods This systematic review followed the PRISMA 2020 guidelines.
Parastoo Amiri, Neda Malek Mohammadi, Mohammad Sharifi, Ali Mohammadi, Hamid Sharifi, Zahra Galavi, Pooria Afsharifard   +6 more
wiley   +1 more source

Keratan Sulfate: An Electroconductive Glycosaminoglycan at the Interface of Sensory Perception and Neural Signaling

Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.
Laboratory studies show KS has electroconductive properties with the ability to trap and transport protons in neurotransductive processes (Grotthuss proton shuttling). This maintains electrochemical gradients and fluxes at the neuronal cell surface in neural activation. Such processes are central to neuronal cell signaling and communication.
James Melrose
wiley   +1 more source

Music processing in behavioural variant frontotemporal dementia and Alzheimer's disease: a functional MRI study. [PDF]

Brain Commun
van 't Hooft JJ, van der Zwaag W, Wink AM, Barkhof F, Schaefer RS, Warren JD, Pijnenburg YAL, Tijms BM.   +7 more
europepmc   +1 more source

Frontotemporal dementia and psychiatry [PDF]

International Review of Psychiatry, 2013
Chiadi U, Onyike, Edward D, Huey
openaire   +2 more sources

The Flail Limb Syndrome

Muscle &Nerve, Volume 74, Issue 2, Page 281-292, August 2026.
ABSTRACT The flail limb syndrome is primarily a lower motor neuron disorder that initially affects proximal arm muscles (flail arm syndrome—FAS) or distal leg muscles (flail leg syndrome—FLS). Both were recognized early on (1886 for FAS and 1918 for FLS) as somewhat distinct from classic amyotrophic lateral sclerosis (ALS).
Mark B. Bromberg
wiley   +1 more source

Eating behaviour profiles across the frontotemporal dementia spectrum. [PDF]

J Neuropsychol
Sato Y, Hayashi H, Kakinuma K, Iseki C, Ota S, Katsuse K, Matsubara S, Kawakami N, Kanno S, Morihara K, Nishio Y, Suzuki K.   +11 more
europepmc   +1 more source