Results 141 to 150 of about 315,827 (302)

Predicting Relevant Microglia‐Associated Cell–Cell Communication Pathways in Alzheimer's Disease: A Role for SPP1

Glia, Volume 74, Issue 10, October 2026.
We used CellChat to infer altered cell–cell communication in Alzheimer's disease Microglia signal to each other via SPP1 in Alzheimer's disease. SPP1‐expressing microglia are present around amyloid‐β plaques. ABSTRACT Microglia play a key role in the pathophysiology of Alzheimer's Disease (AD) and their increased heterogeneity likely affects disease ...
Janssen M. Kotah, Marina Trombetta Lima, Esmée C. Dragt, Asimenia Voulgaroglou, Nieske Brouwer, Inge R. Holtman, Susanne M. Kooistra, Bart J. L. Eggen   +7 more
wiley   +1 more source

Neuropsychiatric symptoms in frontotemporal dementia: a case report

European Psychiatry
Introduction We present the case of a 70-year-old man who, after presenting atypical depressive symptoms, was diagnosed with incipient frontotemporal dementia.
A. Izquierdo De La Puente, P. del Sol Calderón, R. Fernandez Fernandez   +2 more
doaj   +1 more source

Diagnostic accuracy of research criteria for prodromal frontotemporal dementia

: BACKGROUND The Genetic Frontotemporal Initiative Staging Group has proposed clinical criteria for the diagnosis of prodromal frontotemporal dementia (FTD), termed mild cognitive and/or behavioral and/or motor impairment (MCBMI).
Masellis, Mario, Jiskoot, Lize C., Gerhard, Alexander, Bouzigues, Arabella, Convery, Rhian S., Le Ber, Isabelle, Archetti, Silvana, Sogorb-Esteve, Aitana, Galimberti, Daniela, Moreno, Fermin, Sorbi, Sandro, Finger, Elizabeth, Cash, David M., Levin, Johannes, van Swieten, John C, Rowe, James B., Otto, Markus, Benussi, Alberto, Tiraboschi, Pietro, Samra, Kiran, Sanchez-Valle, Raquel, Rohrer, Jonathan D., Gasparotti, Roberto, Grassi, Mario, Vandenberghe, Rik, Graff, Caroline, Todd, Emily G., Gazzina, Stefano, Bocchetta, Martina, Seelaar, Harro, Santana, Isabel, Swift, Imogen, Tartaglia, Maria Carmela, Butler, Chris R., Russell, Lucy L., Laforce, Robert, Synofzik, Matthis, Genetic Frontotemporal Dementia Initiative (GENFI), Ducharme, Simon, Premi, Enrico, Pasquier, Florence, Alberici, Antonella, Padovani, Alessandro, Heller, Carolin, Fumagalli, Giorgio G., Bruffaerts, Rose, Borroni, Barbara, Cantoni, Valentina, Mendon\ue7a, Alexandre   +48 more
core  

Frontotemporal dementia and primary progressive aphasia, a review [PDF]

, 2014
Howard S KirshnerDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN, USAAbstract: Frontotemporal dementias are neurodegenerative diseases in which symptoms of frontal and/or temporal lobe disease are the first signs of the ...
Kirshner HS
core  

A Frontotemporal Dementia with Epilepsia Parsiyalis Continua Responding Lacozamid Treatment

, 2019
Seizures may occur in frontotemporal lobar degeneration syndromes as an element of a heterogeneous group of disorders, according to both clinical phenotype and neuropathology.
DİNÇ, YASEMİN, AKDAĞ, GÖNÜL, Gönül ÇELİK AKDAĞ, Yasemin DİNÇ   +3 more
core   +1 more source

Elevated endogenous glucagon‐like peptide‐1 as a novel Alzheimer's disease biomarker associated with neuroinflammation and Aβ pathology

General Psychiatry, Volume 39, Issue 5, October 2026.
ABSTRACT Background Alzheimer's disease (AD), a neurodegenerative disorder, is pathologically defined by the accumulation of amyloid‐β (Aβ) plaques, hyperphosphorylated tau tangles and sustained neuroinflammation. Glucagon‐like peptide‐1 (GLP‐1), originally characterised as an incretin hormone, is also expressed endogenously in the brain.
Jianping Li, Chenhui Ji, Jintao Wang, Jinwen Xiao, Haixia Li, Xinyi Xie, Nan Zhi, Yaying Song, Wenwei Cao, Liling Wang, Jieli Geng, Rujing Ren, Gang Wang   +12 more
wiley   +1 more source

Current Best Practice for People with Frontotemporal Dementia in Norway: A Focus Group Study with Expert Healthcare Personnel

Dementia and Geriatric Cognitive Disorders Extra
Introduction: Frontotemporal symptoms are usually associated with frontotemporal dementia (FTD), but people with all forms of dementia may develop these symptoms as the dementia disease progresses.
Marit Mjørud, Anne-Brita Knapskog, Marit Nåvik, Janne Røsvik   +3 more
doaj   +1 more source

From Resource Activation to Utilization: A Process‐Outcome Analysis in Telephone‐Based Cognitive‐Behavioral Therapy for Family Caregivers of People With Dementia

Journal of Clinical Psychology, Volume 82, Issue 10, Page 1540-1552, October 2026.
ABSTRACT Objective This study aimed to assess whether resource activation (i.e., fostering strengths and healthy aspects of the patient), aggregated across therapy sessions during telephone‐based cognitive‐behavioral therapy (TEL‐CBT), is associated with post‐therapy psychosocial resource utilization (i.e., the extent to which individuals utilize ...
Nils F. Töpfer, Robin Wester, Gabriele Wilz   +2 more
wiley   +1 more source

Clinical profile, atrophy and inheritance patterns of pathogenic MAPT gene mutations in Frontotemporal dementia detected using whole exome sequencing: a single-center first report from India

BMC Neurology
Background/Objectives Frontotemporal Dementia (FTD) is one of the common causes of early-onset degenerative dementia and is a clinically and pathologically heterogeneous group of neurodegenerative disorders.
Subasree Ramakrishnan, Faheem Arshad, B. S. Keerthana, Susan Bosco, Arun Gokul Pon, V. H. Ganaraja, Deekshitha Madhusudhan, R. Mahima, Gautham Arunachal, Karthick Kulanthaivelu, Suvarna Alladi   +10 more
doaj   +1 more source

Preparing Genetic Counselors for Advocacy Partnerships: A Novel Internship Model

Journal of Genetic Counseling, Volume 35, Issue 5, October 2026.
ABSTRACT Patient advocacy organizations (PAOs) and genetic counseling have expanded in tandem with the growth of precision medicine. Genetic counseling and PAOs share important goals related to advancing genomic medicine, creating novel possibilities for synergistic collaboration, especially as the sheer number of PAOs focused on genetic conditions ...
Marin Kalista, Lisa Jay Kessler, Deborah Requesens, Kathleen D. Valverde, Rebecca Mueller   +4 more
wiley   +1 more source