Results 141 to 150 of about 50,646 (233)

Affective and cognitive theory of mind and associated brain functional alterations in frontotemporal dementia. [PDF]

Brain Commun
Tripodi C, Canu E, Marangon A, Castelnovo V, Basaia S, Spinelli EG, Cecchetti G, Ghirelli A, Pisano S, Rugarli G, Caso F, Magnani G, Caroppo P, Prioni S, Villa C, Tremolizzo L, Appollonio I, Verde F, Ticozzi N, Silani V, Filippi M, Agosta F.   +21 more
europepmc   +1 more source

Exosome‐Mediated Delivery of PROTACs for Targeted Protein Degradation in Cancer, Neurodegenerative, Infectious, and Inflammatory Diseases

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are heterobifunctional molecules that hijack the ubiquitin‐proteasome system to drive catalytic, sub‐stoichiometric degradation of disease‐associated proteins, offering a mechanistic advantage over occupancy‐driven inhibitors and access to ‘undruggable’ targets.
Sruti Bagchi Ghosh, Rumpa Banerjee, Hailah M. Almohaimeed, Amany I. Almars, Tahani Ahmad ALMatrafi, Fayez M. Saleh, Zuhair M. Mohammedsaleh, Kranti Kiran Reddy Ealla, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

Unravelling the Significance of Cystatin C and Bunina Bodies in Amyotrophic Lateral Sclerosis Pathogenesis

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
ABSTRACT Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a fatal neurodegenerative disease primarily affecting motor neurons. Two key protein inclusions found in lower motor neurons serve as neuropathological hallmarks of the disease in human tissue: the TDP43‐positive inclusion and the cystatin C‐positive Bunina body.
Sarah M. Granger, Rosemary A. Staniforth, Asbjorg Osk Snorradottir, Johnathan Cooper‐Knock, Kurt J. De Vos, J. Robin Highley   +5 more
wiley   +1 more source

Correction: EEG-based classification of alzheimer's disease and frontotemporal dementia using functional connectivity. [PDF]

Sci Rep
Mlinarič T, Van Den Kerchove A, Barinaga ZI, Van Hulle MM.   +3 more
europepmc   +1 more source

Frontotemporal Lobar Degeneration‐TDP Type C With Striatal Glial Cytoplasmic Inclusions and Motor Neuron Degeneration

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
We report an autopsy case of frontotemporal lobar degeneration (FTLD)‐TDP type C with severe striatal involvement and annexin A11‐ and phosphorylated TDP‐43‐positive glial cytoplasmic inclusions. The patient developed progressive asymmetric rigidity accompanied by marked striatal atrophy and showed both upper and lower motor neuron involvement.
Akiko Uchino, Kazutomi Kanemaru, Airi Tarutani, Masato Hasegawa, Hiroya Naruse, Hiroyuki Ishiura, Shigeo Murayama, Yuko Saito   +7 more
wiley   +1 more source

Co-morbid seizures in frontotemporal dementia: MRI and PET correlations. [PDF]

Epilepsy Behav Rep
Hashmi SA, Kapur J, Quigg M, D'Abreu A, Manning C, Parikh P, Zawar I.   +6 more
europepmc   +1 more source

Perspectives on Frontotemporal Dementias

The American Journal of Geriatric Psychiatry, 1994
Anand, Kumar, Gary, Gottlieb
openaire   +2 more sources

Biological pathways related to mirna-125a-5p in behavioral variant of frontotemporal dementia. [PDF]

Mol Biol Rep
Pereira JD, Silva LM, Ozawa M, Tosatti JAG, Lima SPO, Silva IR, Jeunon VR, das Graças Carvalho M, de Paula França Resende E, de Souza LC, Caramelli P, Gomes KB.   +11 more
europepmc   +1 more source

Altered amygdala structural connectivity and relations to social cognition in frontotemporal dementia. [PDF]

Alzheimers Dement
Huang M, Dalton MA, Matis S, Teng HAC, Cheung SC, Hwang YT, Ahmed RM, Landin-Romero R, Piguet O.   +8 more
europepmc   +1 more source

Cumulative Incidence in Monogenic Alzheimer's Disease and Frontotemporal Dementia: Gene-Gene Interaction Effect. [PDF]

Int J Mol Sci
Geviti A, Pagano L, Grassi M, Saraceno C, Facconi A, Fostinelli S, Laganà V, Giacomucci G, Cotelli MS, Cantoni V, Ingannato A, Bagnoli S, Bessi V, Longobardi A, Russotto A, Bellini S, Lagrotteria D, Paparazzo E, Binetti G, Montesanto A, Nacmias B, Maletta R, Borroni B, Ghidoni R.   +23 more
europepmc   +1 more source