Results 131 to 140 of about 315,827 (302)
Neuropathology of frontotemporal dementia
Frontotemporal dementia (FTD) is a clinical phenotype of dementia, characterized by complex of clinical symptoms, including disinhibition, character change, increased appetite, sexual misconduct and language problems. Frontotemporal lobar degeneration (FTLD) is a pathological classification of neurodegenerative disorder and its core consists of Pick's ...
openaire +3 more sources
No Evidence for an Association Between DIP2B Repeat Expansion and Neurological Disease
Movement Disorders, EarlyView.
Chia‐Ying Ko +9 more
wiley +1 more source
Abstract Psychometric properties of Tommy's Quest (TQ), a novel serious game to evaluate Theory of Mind (ToM) and the pen‐and‐paper Faux Pas Test (FPT) were assessed. Results from 67 cognitively unimpaired individuals indicated that TQ had adequate construct validity, internal consistency and test–retest reliability.
Jackie M. Poos +7 more
wiley +1 more source
Amyotrophic lateral sclerosis in a combination with frontotemporal dementia: A clinical case study
Objective: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting both central and peripheral motor neurons, presenting a significant challenge in modern neurology. This article discusses the multifactorial nature of ALS,
Nurzhan T. Dzhaparalieva +4 more
doaj +1 more source
Abstract There remains a lack of appropriately adapted neuropsychological tests for culturally, linguistically and educationally diverse populations, particularly for the evaluation of social cognition, as its assessment is essential for the early diagnosis of diseases such as frontotemporal dementia and Alzheimer's disease.
Renelle Bourdage +5 more
wiley +1 more source
Abstract The Ekman 60‐Faces Test is widely used to assess facial emotion recognition, but information on its validity and reliability is scarce. This systematic review evaluated the reporting of psychometric properties across clinical populations. A total of 159 studies (n = 5978) were included: case–control (n = 109), single cohort (n = 37) and review/
Linde Assendelft +2 more
wiley +1 more source
Changes in Nighttime Sleep Duration and Their Association With Cognitive Decline and Dementia Risk
ABSTRACT This study investigates changes in nighttime sleep duration in relation to cognitive decline and risk of incident dementia. A total of 3057 participants from the Swedish population study ‘Good Aging in Skåne’ (Mage = 68.4) with normal baseline sleep duration (6–8 h) were followed up to 20 years (Myears = 8.39). Self‐reported change was defined
Marieclaire Overton +2 more
wiley +1 more source
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
The relationship of dementia prevalence in older adults with intellectual disability (ID) to age and severity of ID [PDF]
Background: Previous research has shown that adults with intellectual disability (ID) may be more at risk of developing dementia in old age than expected. However, the effect of age and ID severity on dementia prevalence rates has never been reported. We
Hassiotis, A. +3 more
core
Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression
Objective Magnetic resonance imaging (MRI)‐visible enlarged perivascular spaces (PVS) are markers of cerebral small vessel disease (SVD) and aging, processes implicated in both neurodegenerative and cerebrovascular pathologies. However, longitudinal positron emission tomography (PET) studies examining PVS as a mechanism underlying Alzheimer's disease ...
Audrey Low +11 more
wiley +1 more source

