Results 131 to 140 of about 329,751 (255)

Frontotemporal Dementia-related glucose metabolic pattern assessed by FDG-PET [PDF]

, 2022
Alzheimer's disease (AD) and Frontotemporal Dementia (FTD) are leading causes of ...
Lau, Angus
core  

Challenges in Gene‐Directed Therapies for Rare Neurodevelopmental Disorders Using HNRNPU as an Exemplar

Clinical Genetics, EarlyView.
Beyond diagnosing rare neurodevelopmental disorders like HNRNPU‐RNDD, developing gene‐directed therapies requires overcoming complex hurdles, including spatial, developmental, and cell‐type constraints. Addressing these requires understanding the molecular effects of dosage and chromatin dynamics to deliver precise, effective treatments.
Daniel Aiyedun, Susan F. Rogers, Doaa M. Taha, Meena Balasubramanian   +3 more
wiley   +1 more source

Selective autophagy pathways in ageing and neurodegeneration: Emerging roles for mitophagy and nucleophagy

The FEBS Journal, EarlyView.
As we age, cells gradually accumulate damage, which can contribute to disease and neurodegeneration. This review explores how two cellular recycling processes, mitophagy and nucleophagy, remove damaged mitochondria and nuclear material, respectively, to maintain cell health and long‐term neuronal homeostasis.
Maria Markaki, Nektarios Tavernarakis
wiley   +1 more source

Mini social cognition and emotional assessment: Diagnostic performance and neural correlates in behavioural‐variant frontotemporal dementia

Journal of Neuropsychology, EarlyView.
Abstract We aimed at validating the Mini Social Cognition and Emotional Assessment (Mini‐SEA) in a German cohort of mildly impaired behavioural‐variant frontotemporal dementia (bvFTD) patients and healthy controls. The Mini‐SEA comprises the Facial Emotion Recognition Test (FERT) and the Faux Pas Test (FPT) measuring Theory of Mind (ToM) abilities in ...
Cem Doğdu, Neeraj Upadhyay, Ingo Frommann, Luca Kleineidam, Andreas Johnen, Melina Stark, Sandra Roeske, Annika Spottke, Anna Gamez, Gabor C. Petzold, Louise Droste zu Senden, Julian Hellmann‐Regen, Stefan Hetzer, Klaus Fliessbach, Carolin Miklitz, Emrah Düzel, Falk Lüsebrink, Wenzel Glanz, Stefan Teipel, Ingo Kilimann, Josef Priller, Eike Jakob Spruth, Johannes Prudlo, David Mengel, Klaus Scheffler, Matthis Synofzik, Anja Schneider, Michael Wagner   +27 more
wiley   +1 more source

Frontotemporal dementia and primary progressive aphasia, a review [PDF]

, 2014
Howard S KirshnerDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN, USAAbstract: Frontotemporal dementias are neurodegenerative diseases in which symptoms of frontal and/or temporal lobe disease are the first signs of the ...
Kirshner HS
core  

Exploring Theory of Mind abilities in patients with probable idiopathic normal pressure hydrocephalus

Journal of Neuropsychology, EarlyView.
Abstract This study investigated Theory of Mind (ToM) deficits in patients with suspected idiopathic normal pressure hydrocephalus (iNPH), a condition affecting motor, cognitive and autonomic functions. Given the overlap between ToM‐related neural networks and those affected in iNPH, we examined whether ToM impairments are a feature of the disease ...
Akrivi Vatsi, George Stranjalis, Stylianos Gkatzonis, Christos Koutsarnakis, Eleftherios Neromyliotis, Aristotelis Kalyvas, Ion N. Beratis, Evangelos Drosos, Spyridon Komaitis, Evangelia Liouta   +9 more
wiley   +1 more source

Diagnostic accuracy of research criteria for prodromal frontotemporal dementia

: BACKGROUND The Genetic Frontotemporal Initiative Staging Group has proposed clinical criteria for the diagnosis of prodromal frontotemporal dementia (FTD), termed mild cognitive and/or behavioral and/or motor impairment (MCBMI).
Masellis, Mario, Jiskoot, Lize C., Gerhard, Alexander, Bouzigues, Arabella, Convery, Rhian S., Le Ber, Isabelle, Archetti, Silvana, Sogorb-Esteve, Aitana, Galimberti, Daniela, Moreno, Fermin, Sorbi, Sandro, Finger, Elizabeth, Cash, David M., Levin, Johannes, van Swieten, John C, Rowe, James B., Otto, Markus, Benussi, Alberto, Tiraboschi, Pietro, Samra, Kiran, Sanchez-Valle, Raquel, Rohrer, Jonathan D., Gasparotti, Roberto, Grassi, Mario, Vandenberghe, Rik, Graff, Caroline, Todd, Emily G., Gazzina, Stefano, Bocchetta, Martina, Seelaar, Harro, Santana, Isabel, Swift, Imogen, Tartaglia, Maria Carmela, Butler, Chris R., Russell, Lucy L., Laforce, Robert, Synofzik, Matthis, Genetic Frontotemporal Dementia Initiative (GENFI), Ducharme, Simon, Premi, Enrico, Pasquier, Florence, Alberici, Antonella, Padovani, Alessandro, Heller, Carolin, Fumagalli, Giorgio G., Bruffaerts, Rose, Borroni, Barbara, Cantoni, Valentina, Mendon\ue7a, Alexandre   +48 more
core  

Frontotemporal dementia [PDF]

Continuum, 2007
Indre Viskontas, Bruce Miller
openaire   +1 more source

Neuropathology of frontotemporal dementia

Rinsho Shinkeigaku, 2008
Frontotemporal dementia (FTD) is a clinical phenotype of dementia, characterized by complex of clinical symptoms, including disinhibition, character change, increased appetite, sexual misconduct and language problems. Frontotemporal lobar degeneration (FTLD) is a pathological classification of neurodegenerative disorder and its core consists of Pick's ...
openaire   +3 more sources

Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated with the pathological variant c.2013T>G in the MAPT gene

Вавиловский журнал генетики и селекции
Frontotemporal dementia with parkinsonism-17 is a neurodegenerative disease characterised by pathological aggregation of the tau protein with the formation of neurofibrillary tangles and subsequent neuronal death.
E. V. Grigor’eva, A. A. Malakhova, E. S. Yarkova, J. M. Minina, Y. V. Vyatkin, J. A. Nadtochy, E. A. Khabarova, J. A. Rzaev, S. P. Medvedev, S. M. Zakian   +9 more
doaj   +1 more source