Results 101 to 110 of about 50,646 (233)

Clinical profile, atrophy and inheritance patterns of pathogenic MAPT gene mutations in Frontotemporal dementia detected using whole exome sequencing: a single-center first report from India

BMC Neurology
Background/Objectives Frontotemporal Dementia (FTD) is one of the common causes of early-onset degenerative dementia and is a clinically and pathologically heterogeneous group of neurodegenerative disorders.
Subasree Ramakrishnan, Faheem Arshad, B. S. Keerthana, Susan Bosco, Arun Gokul Pon, V. H. Ganaraja, Deekshitha Madhusudhan, R. Mahima, Gautham Arunachal, Karthick Kulanthaivelu, Suvarna Alladi   +10 more
doaj   +1 more source

Neuropathology of frontotemporal lobar degeneration: A review

Dementia & Neuropsychologia
Frontotemporal lobar degeneration (FTLD) is the second most common cause of presenile dementia. Three main clinical variants are widely recognized within the FTLD spectrum: the behavioural variant of frontotemporal dementia (bvFTD), semantic dementia (SD)
Valéria Santoro Bahia, Leonel Tadao Takada, Vincent Deramecourt   +2 more
doaj   +1 more source

Psychometric properties of the Ekman 60‐Faces Test in clinical populations: A systematic review and meta‐analysis

Journal of Neuropsychology, EarlyView.
Abstract The Ekman 60‐Faces Test is widely used to assess facial emotion recognition, but information on its validity and reliability is scarce. This systematic review evaluated the reporting of psychometric properties across clinical populations. A total of 159 studies (n = 5978) were included: case–control (n = 109), single cohort (n = 37) and review/
Linde Assendelft, Jackie M. Poos, Esther van den Berg   +2 more
wiley   +1 more source

Differential aspects of familiar people recognition disorders in right and left variants of semantic dementia: A critical review

Journal of Neuropsychology, EarlyView.
Abstract The aim of the present review will consist of discussing the different forms of familiar people recognition disorders observed in the right and left variants of semantic dementia. The review will start with a summary of the main cognitive models of familiar people recognition and of the neuroanatomical correlates of the processing stages ...
Guido Gainotti
wiley   +1 more source

Progress on frontotemporal dementia

Chinese Journal of Contemporary Neurology and Neurosurgery
Frontotemporal dementia (FTD) is the second most common type of early-onset dementia after Alzheimer's disease (AD), severely impairing patients' quality of life and increasing the burden of family care.
XU Yu-xuan, NAN Hai-tian, CHU Min, WU Li-yong   +3 more
doaj   +1 more source

Validation of the German version of the Dimensional Apathy Scale (G‐DAS): Application in amyotrophic lateral sclerosis

Journal of Neuropsychology, EarlyView.
Abstract Apathy is a common behavioural impairment in neurodegenerative conditions and is conceptualized within the Dimensional Apathy Framework as comprising Executive, Emotional and Initiation subtypes. The Dimensional Apathy Scale (DAS) is widely used to assess these domains, yet no validated German version has been available.
Judith Wesenberg, Paula Matthies, Kati Schwiecker, Verena Bittner, Samra Hamzic, Stefan Vielhaber, Ratko Radakovic   +6 more
wiley   +1 more source

Changes in Nighttime Sleep Duration and Their Association With Cognitive Decline and Dementia Risk

Journal of Sleep Research, EarlyView.
ABSTRACT This study investigates changes in nighttime sleep duration in relation to cognitive decline and risk of incident dementia. A total of 3057 participants from the Swedish population study ‘Good Aging in Skåne’ (Mage = 68.4) with normal baseline sleep duration (6–8 h) were followed up to 20 years (Myears = 8.39). Self‐reported change was defined
Marieclaire Overton, Sölve Elmståhl, Rani Basna   +2 more
wiley   +1 more source

Talking therapies for anxiety and depression in people affected by dementia: A scoping meta‐review

Psychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Background Symptoms of anxiety and depression are common in people affected by dementia (people with dementia and family carers). There are many reviews of psychological interventions to reduce stress and distress in people with dementia and family carers, but little cross‐fertilisation with the evidence base underpinning NHS Talking Therapies
Georgina Charlesworth, Cassie Eastham, Lydia Morris   +2 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Predicting Relevant Microglia‐Associated Cell–Cell Communication Pathways in Alzheimer's Disease: A Role for SPP1

Glia, Volume 74, Issue 10, October 2026.
We used CellChat to infer altered cell–cell communication in Alzheimer's disease Microglia signal to each other via SPP1 in Alzheimer's disease. SPP1‐expressing microglia are present around amyloid‐β plaques. ABSTRACT Microglia play a key role in the pathophysiology of Alzheimer's Disease (AD) and their increased heterogeneity likely affects disease ...
Janssen M. Kotah, Marina Trombetta Lima, Esmée C. Dragt, Asimenia Voulgaroglou, Nieske Brouwer, Inge R. Holtman, Susanne M. Kooistra, Bart J. L. Eggen   +7 more
wiley   +1 more source