Results 151 to 160 of about 93,643 (333)

Transcription‐coupled repair: tangled up in convoluted repair

The FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher, Yun Jin Pai, Alex Pines, Wim Vermeulen   +3 more
wiley   +1 more source

Update on the Neuropathological Diagnosis of Frontotemporal Dementias [PDF]

, 2001
John Q. Trojanowski, Dennis W. Dickson
openalex   +1 more source

Type I interferon signalling and interferon‐responsive microglia in health and disease

The FEBS Journal, EarlyView.
Recent insights reveal that type I interferon (IFN‐I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN‐I activity is increasingly linked to neurological dysfunction and neurodegeneration, with microglia as central mediators. This review explores the broader impact of IFN‐I signalling on the nervous system
Jose P. Lopez‐Atalaya, Aysha M. Bhojwani‐Cabrera   +1 more
wiley   +1 more source

A clinical pathological comparison of three families with frontotemporal dementia and identical mutations in the tau gene (P301L)

, 1999
Thomas D. Bird, David Nochlin, Parvoneh Poorkaj, Monique Cherrier, Jeffrey Kaye, Haydeh Payami, Elaine R. Peskind, Thomas H. Lampe, Ellen Nemens, Philip J. Boyer, Daniela Berg   +10 more
openalex   +1 more source

Prion disease resembling frontotemporal dementia and parkinsonism linked to chromosome 17 [PDF]

, 2001
Ricardo Nitríni, Luís Sidônio Teixeira da Silva, Sérgio Rosemberg, Paulo Caramelli, Paulo Eduardo Mestrinelli Carrilho, Paula Iughetti, Maria Rita Passos‐Bueno, Mayana Zatz, Stephen Albrecht, Andréa C. LeBlanc   +9 more
openalex   +1 more source

TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models

The FEBS Journal, EarlyView.
The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir, Joerg Buddenkotte, Majid Ali Alam, Ahmed Own, Randall J. Eck, Brian C. Kraemer, Eckhard Mandelkow, Martin Steinhoff   +7 more
wiley   +1 more source

Frontotemporal dementia and Alzheimer's disease: retrospective differentiation using information from informants.

, 1995
Robert C. Barber, Julie S. Snowden, David Craufurd   +2 more
openalex   +1 more source

Temporal lobe rating scale: application to Alzheimer's disease and frontotemporal dementia [PDF]

, 2001
Clare Galton, Beatriz Gómez‐Ansón, Nagui Antoun, Philip Scheltens, Karalyn Patterson, Martin J. Graves, Barbara J. Sahakian, J. R. Hodges   +7 more
openalex   +1 more source

The Association Between Caregiver Psychosocial Factors and Depressive Symptoms in People With Dementia: A Systematic Review and Meta‐Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To identify and evaluate the magnitude of the association between caregiver psychosocial factors and depressive symptoms among people with dementia. Design Systematic review and meta‐analysis. Methods A systematic review with meta‐analysis used a random‐effects model to estimate the effect size.
Wenjing Ning, Shanshan Wang, Yudi Xu, Daphne Cheung   +3 more
wiley   +1 more source

Which neuropsychiatric and behavioural features distinguish frontal and temporal variants of frontotemporal dementia from Alzheimer's disease?

, 2000
Sasha Bozeat
openalex   +1 more source