Results 161 to 170 of about 98,352 (316)
Abstract We aimed at validating the Mini Social Cognition and Emotional Assessment (Mini‐SEA) in a German cohort of mildly impaired behavioural‐variant frontotemporal dementia (bvFTD) patients and healthy controls. The Mini‐SEA comprises the Facial Emotion Recognition Test (FERT) and the Faux Pas Test (FPT) measuring Theory of Mind (ToM) abilities in ...
Cem Doğdu +27 more
wiley +1 more source
Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations. [PDF]
Loss-of-function mutations in progranulin (GRN) are a major autosomal dominant cause of frontotemporal dementia. Most pathogenic GRN mutations result in progranulin haploinsufficiency, which is thought to cause frontotemporal dementia in GRN mutation ...
Arrant, Andrew E +12 more
core
Abstract The neuropsychological assessment of executive functions is an important part of the diagnostic process for many neurological diseases and for predicting the ability of neurological patients to function independently. Unfortunately, for the majority of commonly used executive function tests there is a paucity of updated normative data ...
Patrick Murphy +2 more
wiley +1 more source
P2‐119: PROTEOMICS‐BASED CSF BIOMARKERS IN FAMILIAL FRONTOTEMPORAL DEMENTIA [PDF]
Nina Rostgaard +4 more
openalex +1 more source
Abstract This study investigated Theory of Mind (ToM) deficits in patients with suspected idiopathic normal pressure hydrocephalus (iNPH), a condition affecting motor, cognitive and autonomic functions. Given the overlap between ToM‐related neural networks and those affected in iNPH, we examined whether ToM impairments are a feature of the disease ...
Akrivi Vatsi +9 more
wiley +1 more source
Abstract Dementia constitutes one of the most widespread neurological disorders, representing an important health concern due to its increasing prevalence. Among the various types of dementia, Alzheimer's disease (AD) is the most common in the elderly, characterized by episodic memory impairment and also a decline in executive functions. Mild cognitive
Luis Heredia +3 more
wiley +1 more source
Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations [PDF]
Hazel Urwin +17 more
openalex +1 more source
Abstract Psychometric properties of Tommy's Quest (TQ), a novel serious game to evaluate Theory of Mind (ToM) and the pen‐and‐paper Faux Pas Test (FPT) were assessed. Results from 67 cognitively unimpaired individuals indicated that TQ had adequate construct validity, internal consistency and test–retest reliability.
Jackie M. Poos +7 more
wiley +1 more source
Abstract There remains a lack of appropriately adapted neuropsychological tests for culturally, linguistically and educationally diverse populations, particularly for the evaluation of social cognition, as its assessment is essential for the early diagnosis of diseases such as frontotemporal dementia and Alzheimer's disease.
Renelle Bourdage +5 more
wiley +1 more source

