Amyotrophic lateral sclerosis in a combination with frontotemporal dementia: A clinical case study
Heart Vessels and TransplantationObjective: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting both central and peripheral motor neurons, presenting a significant challenge in modern neurology. This article discusses the multifactorial nature of ALS,
Nurzhan T. Dzhaparalieva +4 more
doaj +1 more source
O1‐05‐06: Characterization of frontotemporal dementia +/‐ amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72 [PDF]
, 2012 Bradley F. Boeve +10 more
openalex +1 more source
PROTEOMICS, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐bound particles secreted by cells, playing crucial roles in intercellular communication. The composition of EVs can undergo changes in response to stress and disease conditions, making them excellent biomarker candidates.
Panshak P. Dakup +11 more
wiley +1 more source
P4‐259: Different anatomical subtypes of behavioral variant frontotemporal dementia identified using cluster analysis [PDF]
, 2009 Jennifer L. Whitwell +12 more
openalex +1 more source
Phosphodiesterase‐5 Inhibition and Alzheimer's Disease Risk: A Mendelian Randomisation Study
Aging Cell, EarlyView.Preclinical studies suggest PDE5 inhibitors may improve cognition, but observational evidence on Alzheimer's disease (AD) risk is mixed. We performed a cis‐Mendelian randomisation analysis across four AD genome‐wide association studies (GWAS) datasets and a sex‐stratified analysis using UK Biobank data.
Marta Alcalde‐Herraiz +9 more
wiley +1 more source
Academic Emergency Medicine, EarlyView.Abstract Background The increasing prevalence of dementia poses significant challenges for emergency department (ED) care, as persons living with dementia (PLWD) more frequently experience adverse outcomes such as delirium, prolonged stays, and higher mortality rates.
Sangil Lee +20 more
wiley +1 more source
Reply: “PGRN Manifesting as Parkinson's Disease: Counseling and Treatment Implications”
Movement Disorders Clinical Practice, EarlyView.
Angelo Antonini +2 more
wiley +1 more source
Social cognition in Korsakoff's syndrome: A meta‐analysis
Addiction, EarlyView.Abstract Background and aims Korsakoff's syndrome is an alcohol‐related neurocognitive disorder characterized by episodic memory impairments, apathy, confabulations and poor illness‐insight. This meta‐analysis aimed to estimate mean effect sizes of performance in social cognition in people with Korsakoff's syndrome (KS) compared with controls. Method A
Kyra Wijnen +4 more
wiley +1 more source
Dendritic location of dystrophic neurites in FTLD‐TDP type C with annexinopathy
Brain Pathology, EarlyView.The type C variant of FTLD‐TDP (TDP‐C) is defined by long dystrophic neurites that are immunopositive for both phosphorylated TDP and annexin A11 (ANXA11). Kawles et al. are the first paper to systematically show that these neurites are likely of dendritic origin.
Allegra Kawles +10 more
wiley +1 more source
Memory Test Performance on Analogous Verbal and Nonverbal Memory Tests in Patients with Frontotemporal Dementia and Alzheimer's Disease [PDF]
, 2016 Deanna Baldock +3 more
openalex +1 more source