Results 81 to 90 of about 98,352 (316)

Early affective changes and increased connectivity in preclinical Alzheimer's disease. [PDF]

, 2018
IntroductionAffective changes precede cognitive decline in mild Alzheimer's disease and may relate to increased connectivity in a "salience network" attuned to emotionally significant stimuli.
Bilgel, Murat, Brown, Jesse A, Fredericks, Carolyn A, Hua, Alice Y, Resnick, Susan M, Seeley, William W, Sturm, Virginia E, Wong, Dean F   +7 more
core   +1 more source

Serum p‐tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder

Annals of Neurology, EarlyView.
Objective Assess the performance of serum phosphorylated tau 217 (p‐tau217) and neurofilament light chain (NfL) in predicting risk of cognitive impairment or phenoconversion to dementia in individuals with iRBD. Methods We measured serum p‐tau217 and NfL levels by electrochemiluminescence across 4 polysomnographically confirmed iRBD cohorts (n = 300 ...
Shijun Yan, Anis Sahoo, Tanja Zerenner, Kenneth Marek, Michael Sommerauer, Wolfgang Oertel, Michele T. Hu, George K. Tofaris   +7 more
wiley   +1 more source

Examining the propensity and nature of criminal risk behaviours in frontotemporal dementia syndromes and Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Some people with dementia develop changes in behaviour and cognition that may lead to interactions with police or the legal system. However, large, prospective case–control studies examining these behaviours are lacking.
Fiona Kumfor, Grace Wei, Nola Ries, Hayley Bennett, Mirelle D'Mello, Cassandra Kaizik, Olivier Piguet, John R. Hodges   +7 more
doaj   +1 more source

Basal parasympathetic deficits in C9orf72 hexanucleotide repeat expansion carriers relate to smaller frontoinsula and thalamus volume and lower empathy

NeuroImage: Clinical
Diminished basal parasympathetic nervous system activity is a feature of frontotemporal dementia that relates to left frontoinsula dysfunction and empathy impairment.
Ashlin R. K. Roy, Fate Noohi, Nathaniel A. Morris, Peter Ljubenkov, Hilary Heuer, Jamie Fong, Matthew Hall, Argentina Lario Lago, Katherine P. Rankin, Bruce L. Miller, Adam L. Boxer, Howard J. Rosen, William W. Seeley, David C. Perry, Jennifer S. Yokoyama, Suzee E. Lee, Virginia E. Sturm   +16 more
doaj   +1 more source

The effects of context processing on social cognition impairments in adults with Aspergers syndrome [PDF]

, 2014
Social cognition—the basis of all communicative and otherwise interpersonal relationships—is embedded in specific contextual circumstances which shape intrinsic meanings.
Báez Buitrago, Sandra Jimena, Ibañez, Agustin Mariano   +1 more
core   +1 more source

The Phenotypic Spectrum of Sporadic Creutzfeldt‐Jakob Disease Cortical Subtype

Annals of Neurology, EarlyView.
Objective The objective of this study was to characterize the phenotypic spectrum of the rare sporadic Creutzfeldt‐Jakob disease cortical subtype (sCJDMM/MV2C) in a large multicentric autopsy cohort. Methods We evaluated clinical histories, biofluid markers, brain diffusion‐weighted (DW)‐magnetic resonance imaging (MRI), and electroencephalogram (EEG ...
Simone Baiardi, Claudia Marina Vargiu, Brian S. Appleby, Marcelo Barria, Giuseppe Mario Bentivenga, Ignazio Calì, Benedetta Carlà, Mark Cohen, Armin Giese, Jochen Herms, Aino‐Minerva Kortelainen, Anna Ladogana, Angela Mammana, Diane Ritchie, Otto Windl, Sabina Capellari, Piero Parchi   +16 more
wiley   +1 more source

Evaluating combinations of diagnostic tests to discriminate different dementia types

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Introduction We studied, using a data‐driven approach, how different combinations of diagnostic tests contribute to the differential diagnosis of dementia.
Marie Bruun, Hanneke F.M. Rhodius‐Meester, Juha Koikkalainen, Marta Baroni, Le Gjerum, Afina W. Lemstra, Frederik Barkhof, Anne M. Remes, Timo Urhemaa, Antti Tolonen, Daniel Rueckert, Mark vanGils, Kristian S. Frederiksen, Gunhild Waldemar, Philip Scheltens, Patrizia Mecocci, Hilkka Soininen, Jyrki Lötjönen, Steen G. Hasselbalch, Wiesje M. van derFlier   +19 more
doaj   +1 more source

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies [PDF]

, 2016
Acknowledgments This work was supported by The Croatian Science Foundation grant No. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Babić Leko, Mirjana, Bažadona, Danira, Buée, Luc, de Silva, Rohan, Delalle, Ivana, Giovanni, Giuseppe Di, Harrington, Charles, Hof, Patrick R., Jovanov-Milošević, Nataša, Wischik, Claude, Wray, Selina, Šimić, Goran   +11 more
core   +3 more sources

Frontotemporal dementia

Canadian Medical Association Journal, 2023
Medina-Rioja, Raul, Gonzalez-Calderon, Gina, Masellis, Mario   +2 more
openaire   +2 more sources

433 - A possible link between Bipolar Disease and Frontotemporal Dementia [PDF]

, 2021
Beatriz Jorge, Catarina Pedro, José Luís Torres Carvalho, Sara Carneiro, Mariana Duarte Mangas   +4 more
openalex   +1 more source