Results 11 to 20 of about 30,886 (249)

Apraxia phenotypes and frontotemporal lobar degeneration. [PDF]

J Neurol
Langheinrich TC, Thompson JC, Jones M, Richardson AMT, Mann DMA, Snowden JS.   +5 more
europepmc   +2 more sources

TAF15 amyloid filaments in frontotemporal lobar degeneration

Nature, 2023
Frontotemporal lobar degeneration (FTLD) causes frontotemporal dementia (FTD), the most common form of dementia after Alzheimer’s disease, and is often also associated with motor disorders1.
S. Tetter, Diana Arseni, A. Murzin, Y. Buhidma, Sew Y. Peak-Chew, H. Garringer, Kathy L Newell, Ruben Vidal, L. Apostolova, T. Lashley, B. Ghetti, B. Ryskeldi-Falcon   +11 more
semanticscholar   +1 more source

Retina tissue validation of optical coherence tomography determined outer nuclear layer loss in FTLD-tau

Acta Neuropathologica Communications, 2021
Alzheimer’s disease (AD) is associated with inner retina (nerve fiber and ganglion cell layers) thinning. In contrast, we have seen outer retina thinning driven by photoreceptor outer nuclear layer (ONL) thinning with antemortem optical coherence ...
Benjamin J. Kim, Vivian Lee, Edward B. Lee, Adrienne Saludades, John Q. Trojanowski, Joshua L. Dunaief, Murray Grossman, David J. Irwin   +7 more
doaj   +1 more source

MicroRNA biomarkers in frontotemporal dementia and to distinguish from Alzheimer’s disease and amyotrophic lateral sclerosis

Neural Regeneration Research, 2022
Frontotemporal lobar degeneration describes a group of progressive brain disorders that primarily are associated with atrophy of the prefrontal and anterior temporal lobes.
Bridget Martinez, Philip V Peplow
doaj   +1 more source

Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration

Neurology, 2022
Background and Objectives To determine how fully automated Elecsys CSF immunoassays for β-amyloid (Aβ) and tau biomarkers and an ultrasensitive Simoa assay for neurofilament light chain (NFL) correlate with neuropathologic changes of Alzheimer disease ...
N. Mattsson‐Carlgren, L. Grinberg, A. Boxer, R. Ossenkoppele, M. Jonsson, W. Seeley, A. Ehrenberg, S. Spina, S. Janelidze, Julio Rojas-Martinex, H. Rosen, R. La Joie, Orit H Lesman-Segev, Leonardo Iaccarino, Gwendlyn Kollmorgen, P. Ljubenkov, U. Eichenlaub, M. Gorno‐Tempini, B. Miller, O. Hansson, G. Rabinovici   +20 more
semanticscholar   +1 more source

Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration. [PDF]

Nat Aging
Saloner R, Staffaroni AM, Dammer EB, Johnson ECB, Paolillo EW, Wise A, Heuer HW, Forsberg LK, Lario-Lago A, Webb JD, Vogel JW, Santillo AF, Hansson O, Kramer JH, Miller BL, Li J, Loureiro J, Sivasankaran R, Worringer KA, Seyfried NT, Yokoyama JS, Spina S, Grinberg LT, Seeley WW, VandeVrede L, Ljubenkov PA, Bayram E, Bozoki A, Brushaber D, Considine CM, Day GS, Dickerson BC, Domoto-Reilly K, Faber K, Galasko DR, Gendron T, Geschwind DH, Ghoshal N, Graff-Radford N, Hales CM, Honig LS, Hsiung GR, Huey ED, Kornak J, Kremers W, Lapid MI, Lee SE, Litvan I, McMillan CT, Mendez MF, Miyagawa T, Pantelyat A, Pascual B, Masdeu J, Paulson HL, Petrucelli L, Pressman P, Rademakers R, Ramos EM, Rascovsky K, Roberson ED, Savica R, Snyder A, Sullivan AC, Tartaglia MC, Vandebergh M, Boeve BF, Rosen HJ, Rojas JC, Boxer AL, Casaletto KB, ALLFTD Consortium.   +71 more
europepmc   +3 more sources

The role of sequestosome 1/p62 protein in amyotrophic lateral sclerosis and frontotemporal dementia pathogenesis

Neural Regeneration Research, 2020
Amyotrophic lateral sclerosis and frontotemporal lobar degeneration are multifaceted diseases with genotypic, pathological and clinical overlap. One such overlap is the presence of SQSTM1/p62 mutations.
Adriana Delice Foster, Sarah Lyn Rea
doaj   +1 more source

Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration

Neurology, 2021
Objective We tested the hypothesis that plasma neurofilament light chain (NfL) identifies asymptomatic carriers of familial frontotemporal lobar degeneration (FTLD)–causing mutations at risk of disease progression.
J. Rojas, Ping Wang, A. Staffaroni, Carolin Heller, Y. Cobigo, Amy Wolf, Sheng‐Yang M. Goh, P. Ljubenkov, H. Heuer, Jamie C. Fong, Joanne B. Taylor, Eliseo Veras, Linan Song, A. Jeromin, D. Hanlon, Lili Yu, Arvind Khinikar, Rajeev Sivasankaran, A. Kieloch, M. Valentin, A. Karydas, Laura Mitic, Rodney Pearlman, J. Kornak, J. Kramer, B. Miller, K. Kantarci, D. Knopman, N. Graff-Radford, L. Petrucelli, R. Rademakers, D. Irwin, M. Grossman, E. Ramos, G. Coppola, M. Mendez, Y. Bordelon, B. Dickerson, N. Ghoshal, E. Huey, I. Mackenzie, B. Appleby, K. Domoto-Reilly, G. Hsiung, A. Toga, S. Weintraub, D. Kaufer, D. Kerwin, I. Litvan, C. Onyike, A. Pantelyat, E. Roberson, M. Tartaglia, T. Foroud, Weiping Chen, J. Czerkowicz, Danielle L. Graham, J. V. van Swieten, B. Borroni, R. Sánchez-Valle, F. Moreno, R. Laforce, C. Graff, M. Synofzik, D. Galimberti, J. Rowe, M. Masellis, E. Finger, R. Vandenberghe, A. de Mendonça, F. Tagliavini, I. Santana, S. Ducharme, C. Butler, A. Gerhard, J. Levin, A. Danek, M. Otto, S. Sorbi, D. Cash, R. Convery, M. Bocchetta, M. Foiani, C. Greaves, Georgia Peakman, L. Russell, Imogen J. Swift, E. Todd, J. Rohrer, B. Boeve, H. Rosen, A. Boxer   +91 more
semanticscholar   +1 more source

Boundary-based registration improves sensitivity for detecting hypoperfusion in sporadic frontotemporal lobar degeneration. [PDF]

Front Neurol
Mihailescu S, Hlava Q, Cook PA, Mandelli ML, Lee SE, Boeve BF, Dickerson BC, Gorno-Tempini ML, Rogalski E, Grossman M, Gee J, McMillan CT, Olm CA.   +12 more
europepmc   +3 more sources

Syndromes associated with frontotemporal lobar degeneration change response patterns on visual analogue scales

Scientific Reports, 2023
Self-report scales are widely used in cognitive neuroscience and psychology. However, they rest on the central assumption that respondents engage meaningfully.
Rebecca S. Williams, Natalie E. Adams, Laura E. Hughes, Matthew A. Rouse, Alexander G. Murley, Michelle Naessens, Duncan Street, Negin Holland, James B. Rowe   +8 more
doaj   +1 more source