Results 71 to 80 of about 21,838 (240)

Genome and low-iron response of an oceanic diatom adapted to chronic iron limitation [PDF]

, 2012
: BACKGROUND: Biogeochemical elemental cycling is driven by primary production of biomass via phototrophic phytoplankton growth, with 40% of marine productivity being assigned to diatoms.
Andreson, Reidar, Beiko, Robert G, Bergner, Sonja V, Gutowska, Magdalena, Hippler, Michael, Klostermeier, Ulrich C, Kraemer, Lars, LaRoche, Julie, Lommer, Markus, Rosenstiel, Philip, Roy, Alexandra-Sophie, Schilhabel, Markus B, Specht, Michael, Wolf, Juliane   +13 more
core   +2 more sources

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

VIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu, Dan Zhao, Lingyan Zhong, Jianxujie Zheng, Dongxue Zhang, Enhui Wu, Qian Shi, Liang Qiao, Ling Lin   +8 more
wiley   +1 more source

The Effects of Salts and Osmoprotectants on Enzyme Activities of Fructose-1,6-biphosphate Aldolases in a Halotolerant Cyanobacterium, Halothece sp. PCC 7418

Life, 2020
The halotolerant cyanobacterium, Halothece sp. PCC 7418, possesses two classes of fructose-1,6-bisphosphate aldolase (FBA): H2846 and H2847. Though class I (CI)-FBA H2846 is thought to be associated with salt tolerance, the regulatory mechanisms ...
Siripat Ngoennet, Masaki Honda, Tanutcha Patipong, Takashi Hibino, Rungaroon Waditee-Sirisattha, Hakuto Kageyama   +5 more
doaj   +1 more source

Absolute diffusion measurements of active enzyme solutions by NMR

, 2018
The diffusion of enzymes is of fundamental importance for many biochemical processes. Enhanced or directed enzyme diffusion can alter the accessibility of substrates and the organization of enzymes within cells.
Fischer, Peer, Günther, Jan-Philipp, Majer, Günter   +2 more
core   +1 more source

Richard Nelson Perham. 27 April 1937—14 February 2015 [PDF]

, 2018
Richard Nelson Perham, FRS, FMedSci, FRSA, was a British professor of structural biochemistry. He undertook his academic career at the University of Cambridge, holding positions as lecturer, reader, chair and head of the Department of Biochemistry, as ...
Aikens R., Hale G., Radford S. E., Steven A. C., Wilson T. M. A., Wilson T. M. A.   +5 more
core   +3 more sources

Actinomyces spp. gene expression in root caries lesions [PDF]

, 2016
Background: studies of the distribution of Actinomyces spp. on carious and non-carious root surfaces have not been able to confirm the association of these bacteria with root caries, although they were extensively implicated as a prime suspect in root ...
Damé-Teixeira, N, Devine, DA, Do, T, Maltz, M, Parolo, CCF, Tugnait, A   +5 more
core   +2 more sources

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension

Cell Proliferation, EarlyView.
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang, Qing Ni, Yan He, Shijie Liu, Lulu Gan, Anni Dai, Yang Hu, Qian Liu, Xueling Yang, Jiqian Li, Yi Tao, Yunyu Li, Mingyue Xu   +12 more
wiley   +1 more source

SiFBA5, a cold-responsive factor from Saussurea involucrata promotes cold resilience and biomass increase in transgenic tomato plants under cold stress

BMC Plant Biology, 2021
Background Saussurea involucrata survives in extreme arctic conditions and is very cold-resistant. This species grows in rocky, mountainous areas with elevations of 2400–4100 m, which are snow-covered year-round and are subject to freezing temperatures ...
Jianqiang Mu, Yajuan Fu, Bucang Liu, Yao Zhang, Aiying Wang, Yuxia Li, Jianbo Zhu   +6 more
doaj   +1 more source

Identification of hub genes in the fructose-1, 6 bisphosphate 1-protein interaction network based on differential expression, and survival impact on hepatocellular carcinoma patients

Biomedical and Biotechnology Research Journal, 2023
Background: Hepatocytes, the cells of origin in hepatocellular carcinoma (HCC), accompany several altered metabolic pathways leading to adaptive metabolic switch and uncontrolled cell proliferation.
Bhavya Dawath, Harshal Patole, Norine Dsouza, Kripa Purohit, Shiney Peter   +4 more
doaj   +1 more source