Results 51 to 60 of about 13,839 (206)

Structure-based prediction and identification of 4-epimerization activity of phosphate sugars in class II aldolases

open access: yesScientific Reports, 2017
Sugar 4-epimerization reactions are important for the production of rare sugars and their derivatives, which have various potential industrial applications.
Seon-Hwa Lee   +6 more
doaj   +1 more source

Glycolytic biomarkers predict transformation in patients with follicular lymphoma.

open access: yesPLoS ONE, 2020
Follicular lymphoma (FL) is an indolent neoplasia comprising approximately 20% of lymphomas. FL is generally considered incurable, with a median survival exceeding 10 years.
Ida Monrad   +7 more
doaj   +1 more source

Import of fructose bisphosphate aldolase into the glycosomes of Trypanosoma brucei. [PDF]

open access: yesThe Journal of cell biology, 1987
The glycolytic enzymes of Trypanosomatids are compartmentalized within peroxisome-like microbodies called glycosomes. Fructose bisphosphate aldolase is synthesized on free polysomes and imported into glycosomes within 5 min. Peptide mapping reveals no primary structural differences between the in vivo-synthesized protein and that made in vitro from a ...
openaire   +2 more sources

Simultaneous purification of hexokinase, class-I fructose-bisphosphate aldolase, triosephosphate isomerase and phosphoglycerate kinase from Trypanosoma brucei. [PDF]

open access: yes, 1984
A method is presented for the simultaneous purification of hexokinase, fructose-bisphosphate aldolase, triosephosphate isomerase and phosphoglycerate kinase, and the partial purification of glycerol-3-phosphate dehydrogenase (NAD+), 6-phosphofructokinase,
Misset, O., Opperdoes, Frederik
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

The dhnA gene of Escherichia coli encodes a Class I fructose bisphosphate aldolase [PDF]

open access: yesBiochemical Journal, 1998
The gene encoding the Escherichia coli Class I fructose-1,6-bisphosphate aldolase (FBP aldolase) has been cloned and the protein overproduced in high amounts. This gene sequence has previously been identified as encoding an E. coli dehydrin in the GenBank™ database [gene dhnA; entry code U73760; Close and Choi (1996) Submission to GenBank™].
G J, Thomson   +3 more
openaire   +2 more sources

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco   +7 more
wiley   +1 more source

Fructose-bisphosphate aldolase and pyruvate kinase, two novel immunogens inMadurella mycetomatis [PDF]

open access: yesMedical Mycology, 2012
Eumycetoma, a chronic granulomatous disease characterized by a subcutaneous mass, multiple sinuses and purulent discharge containing grains, remains difficult to diagnose and treat. Madurella mycetomatis is the most common causative agent of eumycetoma. Using a serum pool from patients with active mycetoma, we screened a M.
de Klerk, N   +4 more
openaire   +3 more sources

Human aldolase C: gene transcriptional regulation and protein functional role [PDF]

open access: yes, 2011
Aldolase C is the brain-specific aldolase isoenzyme. In the human brain, aldolase C messenger and protein are expressed in a stripe-like pattern in the Purkinje cells of the cerebellum, in the inferior olives and in the Goll and Burdach nuclei of the ...
Serio, Laura
core  

The crystal structure of fructose-1,6-bisphosphate aldolase fromDrosophila melanogaster at 2.5A˚resolution [PDF]

open access: yes, 1991
The structure of fructose-1,6-bisphosphate aldolase fromDrosophila melanogaster has been determined by X-ray diffraction at 2.5A˚resolution. The insect enzyme crystallizes in space groupP212121 with lattice constantsa=86.60,b=116.80,c=151.58A˚. Molecular
Smit, Jan Derk G.   +6 more
core   +1 more source

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