Results 41 to 50 of about 297,630 (302)
Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis [PDF]
, 2013 Previous models of glycolysis in the sleeping sickness parasite Trypanosoma brucei assumed that the core part of glycolysis in this unicellular parasite is tightly compartimentalized within an organelle, the glycosome, which had previously been shown to ...
Achcar +30 more
core +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Simvastatin-induced cardiac autonomic control improvement in fructose-fed female rats
Clinics, 2011 OBJECTIVE: Because autonomic dysfunction has been found to lead to cardiometabolic disorders and because studies have reported that simvastatin treatment has neuroprotective effects, the objective of the present study was to investigate the effects of ...
Renata Juliana da Silva +5 more
doaj +1 more source
Sugar metabolism and accumulation in the fruit of transgenic apple trees with decreased sorbitol synthesis. [PDF]
, 2018 Both sorbitol and sucrose are synthesized in source leaves and transported to fruit for supporting fruit growth in tree fruit species of the Rosaceae family.
Cheng, Lailiang +4 more
core +2 more sources
Arthritis Care &Research, EarlyView.Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette +13 more
wiley +1 more source
Cherry and fresh market tomatoes: Differences in chemical, morphological, and sensory traits and their implications for consumer acceptance [PDF]
, 2019 The tomato commercial groups cherry and fresh market, mainly classified by fruit size, have clearly segregated markets. We aimed to estimate the variation within and between these groups and to analyze factors that impact consumer acceptance. To this end,
Casals Missio, Joan +4 more
core +2 more sources
Advanced Engineering Materials, EarlyView.The presented study focuses on the fracture behaviour of carbon‐bonded magnesia MgO–C refractories, where environmentally friendly fructose, collagen and lignin serve as temporary binding agents. The partial substitution of the source material with recycled MgO–C reduces the fracture resistance, which can be counteracted by the additional introduction ...
Marc Neumann +6 more
wiley +1 more source
Acta Agriculturae Slovenica, 2021 Codling moth (Cydia pomonella [L.]) is the most serious pest of apple worldwide. Its control still relies largely on insecticide applications. To deal with this situation, it becomes essential to design eco-friendly control systems to minimize chemical ...
Abdelkader Nabil TIFFRENT +1 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.Carbon‐free inert anodes are essential for decarbonizing aluminum electrolysis. This study investigates a recyclate‐based MgO‐316L steel composite anode tested under galvanostatic Hall–Héroult conditions in cryolite at 1000°C. Microstructural analysis reveals selective MgO fluorination, spinel and oxide layer formation, electrolyte infiltration, and ...
Serhii Yaroshevskyi +7 more
wiley +1 more source
Cardiovascular autonomic dysfunction and oxidative stress induced by fructose overload in an experimental model of hypertension and menopause [PDF]
, 2014 Background: Metabolic syndrome is characterized by the association of 3 or more risk factors, including: abdominal obesity associated with an excess of abdominal fat, insulin resistance, type 2 diabetes, dyslipidemia and hypertension.
Bernardes, Nathalia +8 more
core +2 more sources