Results 81 to 90 of about 395,783 (395)

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

open access: yesAdvanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang   +8 more
wiley   +1 more source

ANGPTL3 orchestrates hepatic fructose sensing and metabolism

open access: yesCell Reports
Summary: Fructose metabolism is linked to metabolic dysfunction-associated steatotic liver disease (MASLD), but the regulatory mechanisms governing fructose uptake remain poorly understood.
Meng Zhao   +9 more
doaj   +1 more source

Sugar-Mediated Green Synthesis of Silver Selenide Semiconductor Nanocrystals under Ultrasound Irradiation

open access: yesMolecules, 2020
Silver selenide (Ag2Se) is a promising nanomaterial due to its outstanding optoelectronic properties and countless bio-applications. To the best of our knowledge, we report, for the first time, a simple and easy method for the ultrasound-assisted ...
Daniela Armijo García   +9 more
doaj   +1 more source

Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease

open access: yesNutrients, 2017
Increased fructose consumption has been suggested to contribute to non-alcoholic fatty liver disease (NAFLD), dyslipidemia, and insulin resistance, but a causal role of fructose in these metabolic diseases remains debated.
K. T. ter Horst, M. Serlie
semanticscholar   +1 more source

Coupling Nitrogenous Organic Wastewater Treatment and Biorefinery via N‐Cycling Bacterium

open access: yesAdvanced Science, EarlyView.
The vast reservoir of nitrogenous organic pollutants in industrial wastewaters can serve as untapped carbon‐nitrogen resources. This study employs the newly discovered Paracoccus sp. ZQW‐1 as a versatile chassis to simultaneously achieve N‐methylpyrrolidone (NMP) wastewater depuration and polyhydroxybutyrate (PHB) synthesis.
Ziqian Wang   +3 more
wiley   +1 more source

Organismal Fructose Metabolism in Health and Non-Alcoholic Fatty Liver Disease

open access: yesBiology, 2020
NAFLD has alarmingly increased, yet FDA-approved drugs are still lacking. An excessive intake of fructose, especially in liquid form, is a dietary risk factor of NAFLD. While fructose metabolism has been studied for decades, it is still controversial how
Shea Skenderian   +2 more
doaj   +1 more source

Sweet but Bitter: Focus on Fructose Impact on Brain Function in Rodent Models

open access: yesNutrients, 2020
Fructose consumption has drastically increased during the last decades due to the extensive commercial use of high-fructose corn syrup as a sweetener for beverages, snacks and baked goods. Fructose overconsumption is known to induce obesity, dyslipidemia,
M. Spagnuolo, S. Iossa, L. Cigliano
semanticscholar   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

open access: yesAdvanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao   +16 more
wiley   +1 more source

Fructose malabsorption and fructan malabsorption are associated in patients with irritable bowel syndrome

open access: yesBMC Gastroenterology
Background Food malabsorption and intolerance is implicated in gastrointestinal symptoms among patients with irritable bowel syndrome (IBS). Key triggers include fructose and fructan.
Twan Sia   +18 more
doaj   +1 more source

Acrylamide formation in potato products [PDF]

open access: yes, 2006
End of Project ReportAcrylamide, a substance classified as a potential carcinogen, occurs in heated starchy foods at concentrations many times in excess of levels permitted in drinking water. Early surveys indicated that levels of acrylamide in potato
Brunton, Nigel   +5 more
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