Atenolol increases dental mineralization in male offspring of treated hypertensive rats and normotensive rats [PDF]
Brazilian Oral Research, 2020 This study evaluates how atenolol affects dental mineralization in offspring of female spontaneously hypertensive rats (fSHR) and normotensive Wistar rats (fW). fSHR and fW were treated with atenolol (100 mg/Kg/day, orally) during pregnancy and lactation.
Gracieli Prado ELIAS +4 more
doaj +1 more source
Translational Medicine of Aging, 2023 Follicle-stimulation hormone (FSH) and FSH receptor (FSHR) signaling is essential for lifelong ovarian and endocrine functions in females. Previous studies have reported that Fshr haploinsufficiency in female mice led to accelerated ovarian aging ...
Kristen Mehalko +5 more
doaj +1 more source
eLife assessment: Atlas of Fshr expression from novel reporter mice
Dolores Shoback
openalex +2 more sources
Male infertility and FSHR gene polymorphisms in IVF [PDF]
Fertility and Sterility, 2016 I. Zhylkova, O. Feskov
openalex +2 more sources
FSHR antagonists can trigger a PCOS-like state
Systems Biology in Reproductive Medicine, 2021 Over the recent years, FSHR has become an important target for development of fertility regulating agents, as impairment of FSH-FSHR interaction can lead to subfertility or infertility. In our previous study, we identified a 9-mer peptide (FSHβ (89–97)) that exhibited FSHR antagonist activity.
Faiza Hanif, Waghu +6 more
openaire +2 more sources
Reproductive physiology in young men is cumulatively affected by FSH-action modulating genetic variants: FSHR -29G/A and c.2039 A/G, FSHB -211G/T. [PDF]
PLoS ONE, 2014 Follicle-Stimulating Hormone Receptor (FSHR) -29G/A polymorphism (rs1394205) was reported to modulate gene expression and reproductive parameters in women, but data in men is limited.
Marina Grigorova +8 more
doaj +1 more source
The G-protein coupled estrogen receptor (GPER/GPR30) is a gonadotropin receptor dependent positive prognosticator in ovarian carcinoma patients. [PDF]
PLoS ONE, 2013 Follicle stimulating hormone receptor (FSHR) and luteinizing hormone receptor (LHCGR) were demonstrated to impact upon survival of patients suffering from epithelial ovarian cancer (EOC).
Sabine Heublein +6 more
doaj +1 more source
Responsiveness of bovine cumulus-oocyte-complexes (COC) to porcine and recombinant human FSH, and the effect of COC quality on gonadotropin receptor and Cx43 marker gene mRNAs during maturation in vitro [PDF]
, 2003 Substantially less development to the blastocyst stage occurs in vitro than in vivo and this may be due to deficiencies in oocyte competence. Although a large proportion of bovine oocytes undergo spontaneous nuclear maturation, less is known about ...
Calder, Michele D +3 more
core +4 more sources
RANKL is a new epigenetic biomarker for the vasomotor symptom during Menopause
Balkan Journal of Medical Genetics, 2020 During menopausal transition, decreased level of estrogen brings a number of physiological problems and hormonal changes. In this study, promoter methylation of RANKL and FSHR genes were identified in 30 premenopausal and 35 postmenopausal women using ...
Kalkan R, Altarda M, Tosun O
doaj +1 more source
BPA-Induced Deregulation of Epigenetic Patterns: Effects on Female Zebrafish Reproduction [PDF]
, 2016 Bisphenol A (BPA) is one of the commonest Endocrine Disruptor Compounds worldwide. It interferes with vertebrate reproduction, possibly by inducing deregulation of epigenetic mechanisms.
Carnevali, Oliana +6 more
core +1 more source