Results 151 to 160 of about 30,141 (201)
Lipid Metabolic Alterations in the ALS–FTD Spectrum of Disorders [PDF]
Biomedicines, 2022 There is an increasing interest in the study of the relation between alterations in systemic lipid metabolism and neurodegenerative disorders, in particular in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD).
Juan MIGUEL Godoy-Corchuelo +2 more
exaly +2 more sources
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy
Autophagy, 2019 Mutations in C9orf72 leading to hexanucleotide expansions are the most common genetic causes for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Yee Kit Tai, Song Chen, Jun-Lin Guan
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
The endolysosomal pathway and ALS/FTD
Trends in Neurosciences, 2023Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are considered to be part of a disease spectrum that is associated with causative mutations and risk variants in a wide range of genes. Mounting evidence indicates that several of these genes are linked to the endolysosomal system, highlighting the importance of this pathway in ALS ...
Tiffany W. Todd +3 more
openaire +2 more sources
Alzheimer's & Dementia, 2023
AbstractBackgroundThe burden of dementia in India is estimated to increase by 197% by 2050, and Frontotemporal dementia (FTD) is among the leading causes of young‐onset dementia. With recent advances in molecular pathology, genetic mechanisms and emerging therapies in FTD, it is important to understand familial FTD patterns in the heterogeneous ...
Suvarna Alladi +2 more
openaire +1 more source
AbstractBackgroundThe burden of dementia in India is estimated to increase by 197% by 2050, and Frontotemporal dementia (FTD) is among the leading causes of young‐onset dementia. With recent advances in molecular pathology, genetic mechanisms and emerging therapies in FTD, it is important to understand familial FTD patterns in the heterogeneous ...
Suvarna Alladi +2 more
openaire +1 more source
Journal of Neurology, Neurosurgery & Psychiatry, 2020
The frontotemporal dementias (FTDs) are a group of disorders linked by presentation features combining executive, language and behavioural dysfunction. FTD includes three main clinical syndromes: behavioural variant FTD (bvFTD), semantic dementia and progressive agrammatic/non-fluent aphasia.
openaire +2 more sources
The frontotemporal dementias (FTDs) are a group of disorders linked by presentation features combining executive, language and behavioural dysfunction. FTD includes three main clinical syndromes: behavioural variant FTD (bvFTD), semantic dementia and progressive agrammatic/non-fluent aphasia.
openaire +2 more sources
African American experience of FTD: A sub‐cohort assessment of the FTD Insights Survey
Alzheimer's & Dementia, 2022AbstractBackgroundWhile efforts are underway to better understand the prevalence, incidence, pathophysiology, and phenomenology of FTD, most research participation has been dominated by persons of European descent. Better understanding of early signs, the diagnostic journey, and the functional impacts in historically underrepresented groups may help ...
Shana G. Dodge +3 more
openaire +1 more source
An Epigenetic Spin to ALS and FTD
2018Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating and lethal neurodegenerative diseases seen comorbidly in up to 15% of patients. Despite several decades of research, no effective treatment or disease-modifying strategies have been developed.
Mark T W, Ebbert +2 more
openaire +2 more sources