Results 1 to 10 of about 17,332 (168)

GRN is a prognostic biomarker and correlated with immune infiltration in glioma: A study based on TCGA data

Frontiers in Oncology, 2023
BackgroundAmong primary brain tumors, gliomas are associated with a poor prognosis and a median survival that varies depending on the tumor grade and subtype.
Dai Li
exaly   +3 more sources

Coronary Computer Tomography Angiography in 2021—Acquisition Protocols, Tips and Tricks and Heading beyond the Possible

Diagnostics, 2021
Recent technological advances, together with an increasing body of evidence from randomized trials, have placed coronary computer tomography angiography (CCTA) in the center of the diagnostic workup of patients with coronary artery disease.
Sorin Giusca, Moritz Schütz, Florian Kronbach, David Wolf, Peter Nunninger, Grigorios Korosoglou   +5 more
doaj   +1 more source

Public Protection and Disaster Relief Planning Using Terrestrial Trunked Radio in West Java

JOIV: International Journal on Informatics Visualization, 2022
This research aims to implement Public Protection and Disaster Relief (PPDR) planning using Terrestrial Trunked Radio (TETRA) in the West Java area. This plan will work at frequencies 806-821 MHz and 851-866 MHz (bandwidth of 15 MHz). PPDR planning study
Tengku Ahmad Riza, Asep Mulyana, Rendy Munadi   +2 more
doaj   +1 more source

Case Report: Disappearance of Late Gadolinium Enhancement and Full Functional Recovery in a Young Patient With SARS-CoV-2 Vaccine-Related Myocarditis

Frontiers in Cardiovascular Medicine, 2022
Acute myocarditis was recently demonstrated in previously healthy young male patients after receipt of mRNA SARS-CoV-2 vaccines. Herein, we report on a 21-year-old man who presented with acute fatigue, myalgia, and chest pain 2 days after his second SARS-
Grigorios Korosoglou, Grigorios Korosoglou, Peter Nunninger, Sorin Giusca, Sorin Giusca   +4 more
doaj   +1 more source

Plasma lysosphingolipids in GRN-related diseases: Monitoring lysosomal dysfunction to track disease progression

Neurobiology of Disease, 2023
GRN mutations are among the main genetic causes of frontotemporal dementia (FTD). Considering the progranulin involvement in lysosomal homeostasis, we aimed to evaluate if plasma lysosphingolipids (lysoSPL) are increased in GRN mutation carriers, and ...
Walid Khrouf, Dario Saracino, Benoit Rucheton, Marion Houot, Fabienne Clot, Daisy Rinaldi, Joana Vitor, Marie Huynh, Evelyne Heng, Dimitri Schlemmer, Florence Pasquier, Vincent Deramecourt, Sophie Auriacombe, Carole Azuar, Richard Levy, Stéphanie Bombois, Claire Boutoleau-Brétonnière, Jérémie Pariente, Mira Didic, David Wallon, Frédérique Fluchère, Stéphane Auvin, Imen Ben Younes, Yann Nadjar, Alexis Brice, Bruno Dubois, Dominique Bonnefont-Rousselot, Isabelle Le Ber, Foudil Lamari   +28 more
doaj   +1 more source

Successful Conservative Treatment of Mobile Aortic Thrombus Causing Acute Limb Ischemia

JACC: Case Reports, 2023
In this clinical vignette, we present the case of an 83-year-old female patient with acute limb ischemia, resulting from a large (1.8 × 2.8 cm) mobile thrombus in the descending aorta.
Dimitrios Mouselimis, MD, Alexander Giesen, MD, Konstantinos P. Donas, MD, Grigorios Korosoglou, MD   +3 more
doaj   +1 more source

Case report: Case series of isolated acute pericarditis after SARS-CoV-2 vaccinations

Frontiers in Cardiovascular Medicine, 2022
During the worldwide ongoing immunization campaign against SARS-CoV-2, growing data on very rare but potentially harmful side effects of such vaccines arise since approval trials have not been adequately powered to detect those events.
Marco M. Ochs, Markus Haass, Saskia Hagstotz, Sorin Giusca, Grigorios Korosoglou, Grigorios Korosoglou, Grigorios Korosoglou   +6 more
doaj   +1 more source

Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice

Acta Neuropathologica Communications, 2021
Frontotemporal lobar degeneration (FTLD) causes a spectrum of clinical presentations of frontotemporal dementia (FTD), including progressive changes in behavior, personality, executive function, and language.
Jonathan Frew, Haakon Berge Nygaard
doaj   +1 more source

Temporal dynamics of a CSF1R signaling gene regulatory network involved in epilepsy.

PLoS Computational Biology, 2021
Colony Stimulating Factor 1 Receptor (CSF1R) is a potential target for anti-epileptic drugs. However, inhibition of CSF1R is not well tolerated by patients, thereby prompting the need for alternative targets.
Claude Gérard, Laurane De Mot, Sabine Cordi, Jonathan van Eyll, Frédéric P Lemaigre   +4 more
doaj   +1 more source

Aborted Sudden Cardiac Death in a Female Patient Presenting with Takotsubo-Like Cardiomyopathy due to Epicardial Coronary Vasospasm

Case Reports in Cardiology, 2017
Takotsubo cardiomyopathy is characterized by apical ballooning of the left ventricle (LV) in the absence of relevant coronary artery stenosis, which typically occurs in elderly women after emotional stress.
Sorin Giusca, Tom Eisele, Peter Nunninger, Benedikt Münz, Grigorios Korosoglou   +4 more
doaj   +1 more source