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Assessment of Early Fuchs Endothelial Corneal Dystrophy and CTG Trinucleotide Expansion Positivity Using Scheimpflug Imaging [PDF]

Ophthalmology Science
Purpose: To evaluate changes in corneal densitometry and optical aberrations using Scheimpflug imaging in early Fuchs endothelial corneal dystrophy (FECD) and to assess their association with CTG trinucleotide repeat expansion.
Stanley S.J. Poh, MBBS, Kai Yuan Tey, MBBS, Gary S.L. Peh, PhD, Dawn J.H. Neo, MSc, Hla Myint Htoon, PhD, Evan K.L. Lee, Yu Qiang Soh, MBBS, V Vinod Mootha, MD, Jodhbir S. Mehta, PhD   +8 more
doaj   +2 more sources

Rho-Kinase Inhibitors in the Management of Fuchs Endothelial Corneal Dystrophy: A Review [PDF]

Medicina
Fuchs endothelial corneal dystrophy (FECD) is the most common corneal endothelial dystrophy. It is characterized by the progressive loss of corneal endothelial cells (CECs), guttae formation on the Descemet membrane, and corneal edema, leading to visual ...
Anđela Jukić, Ana Pupić Bakrač, Biljana Đapic Ivančić, Andrijana Kopić, Ana Meter, Rajka Kasalica Žužul, Josip Pavan, Tomislav Jukić   +7 more
doaj   +2 more sources

Fuchs Endothelial Corneal Dystrophy Associations with Systemic Disease, Lifestyle, and Nutritional Intake [PDF]

Ophthalmology Science
Objective: To evaluate associations between Fuchs endothelial corneal dystrophy (FECD) and systemic comorbidities, lifestyle factors, and dietary patterns, aiming to identify modifiable risk factors and inform therapeutic strategies. Design: Case-control
Myriam Böhm, MD, MSc, Aaron R. Kaufman, MD, Francesca Kahale, MD, Pia Leon, MD, Viridiana Kocaba, MD, PhD, Ula V. Jurkunas, MD   +5 more
doaj   +2 more sources

Changing trends in penetrating keratoplasty indications at a tertiary eye care center in Budapest, Hungary between 2006 and 2017 [PDF]

International Journal of Ophthalmology, 2020
AIM: To analyze the changing trends in penetrating keratoplasty (PKP) indications. METHODS: This retrospective study included all patients with PKP between 2006 and 2017. Patients were classified using histological diagnoses.
Milán Tamás Pluzsik, Gábor Tóth, Jeannette Tóth, András Matolcsy, Achim Langenbucher, Ágnes Kerényi, Zoltán Zsolt Nagy, Nóra Szentmáry   +7 more
doaj   +1 more source

Genetic mutations and molecular mechanisms of Fuchs endothelial corneal dystrophy

Eye and Vision, 2021
Background Fuchs endothelial corneal dystrophy is a hereditary disease and the most frequent cause of corneal transplantation in the worldwide. Its main clinical signs are an accelerated decrease in the number of endothelial cells, thickening of Descemet’
Xuerui Liu, Tao Zheng, Chuchu Zhao, Yi Zhang, Hanruo Liu, Liyuan Wang, Ping Liu   +6 more
doaj   +1 more source

Rate of Cornea Endothelial Cell Loss and Biomechanical Properties in Fuchs' Endothelial Corneal Dystrophy

Frontiers in Medicine, 2021
Background: Our study aimed to determine the correlation between the clinical staging of Fuchs' endothelial corneal dystrophy (FECD), rate of endothelial cell loss, and corneal biomechanical properties.Methods: This study combined a longitudinal ...
Usanee Reinprayoon, Usanee Reinprayoon, Monthira Jermjutitham, Ngamjit Kasetsuwan, Ngamjit Kasetsuwan   +4 more
doaj   +1 more source

The comorbidity of keratoconus and Fuchs’ endothelial corneal dystrophy (clinical cases)

Офтальмохирургия, 2021
Purpose. To describe the clinical cases and surgery results in patients with concomitant of keratoconus and Fuchs’ corneal endothelial dystrophy. Material and methods. Retrospective analysis of 3 patients using different surgical techniques. All patients
B. E. Malyugin, O. P. Antonova, Z. R. Ebzeeva   +2 more
doaj   +1 more source

Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells

Redox Biology, 2020
Corneal transparency is maintained by a monolayer of corneal endothelial cells. Defects in corneal endothelial cells (CEnCs) can be rectified surgically through transplantation.
Matthew Lovatt, Khadijah Adnan, Viridiana Kocaba, Martin Dirisamer, Gary S.L. Peh, Jodhbir S. Mehta   +5 more
doaj   +1 more source

Application of convolutional neural networks to define Fuchs endothelial dystrophy

Офтальмохирургия, 2022
Purpose. To evaluate the application of convolutional neural networks for the automatic detection of Fuchs’ dystrophy. Material and methods. The study included 700 biomicroscopic images of the corneal endothelium (Tomey EM-3000) randomly selected from ...
S.V. Shukhaev, E.A. Mordovtseva, E.A. Pustozerov, S.S. Kudlakhmedov   +3 more
doaj   +1 more source

Еvaluate the Effectiveness of Accelerated Collagen Crosslinking in the Treatment of Corneal Endothelial Decompensation

Oftalʹmologiâ, 2020
The article discusses the effectiveness of accelerated collagen crosslinking in the treatment of patients with corneal diseases, a common basic pathogenetic link of which is endothelial corneal decompensation.
S. Yu. Astakhov, S. A. Novikov, S. S. Papanyan, I. A. Riks   +3 more
doaj   +1 more source