Synthesis of Fucose Derivatives with Thiol Motifs towards Suicide Inhibition of Helicobacter pylori
The syntheses of six thiol-exhibiting monosaccharides towards suicide inhibition of Helicobacter pylori are reported. Blood group Antigen Binding Adhesin (BabA), a bacterial membrane-bound lectin, binds to human ABO and Lewis b blood group structures ...
Mark Reihill+3 more
doaj +1 more source
Pectic enzymes as potential enhancers of ascorbic acid production through the D-galacturonate pathway in Solanaceae [PDF]
The increase of L-Ascorbic Acid (AsA) content in tomato (Solanum lycopersicum) is a common goal in breeding programs due to its beneficial effect on human health.
Barone, Amalia+4 more
core +2 more sources
Engineering antibodies with cancer‐associated binding sites
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian+4 more
wiley +1 more source
Performance and intestinal responses to dehulling and inclusion level of Australian sweet lupins (Lupinus angustifolius L.) in diets for weaner pigs [PDF]
A total of 180 entire male weaner pigs weighing 6.4 ± 0.1. kg (mean ± SEM) and housed in pairs was used in a completely randomised block design with 9 dietary treatments (n= 10 pens). Pigs were blocked based on weaning weight.
Heo, J.M.+3 more
core +2 more sources
Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli
This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa+3 more
wiley +1 more source
Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin+5 more
wiley +1 more source
Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells. [PDF]
Alpha1,2-fucosyltransferases, FUT1 and FUT2, which transfer fucoses onto the terminal galactose of N-acetyl-lactosamine via α1,2-linkage have been shown to be highly expressed in various types of cancers.
Cho, Huan-Chieh+5 more
core
Discovery of Serotransferrin Glycoforms: Novel Markers for Diagnosis of Liver Periductal Fibrosis and Prediction of Cholangiocarcinoma. [PDF]
Cholangiocarcinoma (CCA) caused by chronic liver fluke infection is a major public health problem in Northeast Thailand. Identification of CCA risk groups is urgently needed for the control of CCA in this region.
Barboza, Mariana+10 more
core +2 more sources
Citrus IntegroPectin: A Family of Bioconjugates With Large Therapeutic Potential
Abstract Citrus IntegroPectin is a family of bioconjugates sourced from different citrus fruits first isolated in 2019 via hydrodynamic cavitation of industrial citrus processing biowaste conducted in water only. Having a low methoxyl homogalacturonan backbone, these new pectins are enriched in citrus flavonoids, terpenes, and RG‐I rhamnogalacturonan ...
Rosaria Ciriminna+7 more
wiley +1 more source
Changes in heparin- and lectin-binding activity of fibronectin in proliferative blood diseases
Fibronectin concentration, its heparin-binding activity and interaction with Lens Culinaris Agglutinin (LCA), Aleuria Aurantia Lectin (AAL) and Laburnum Anagyroides Agglutinin (LABA) in patients with erythremia and subleukemic myelosis were investigated.
A. O. Kulinich+4 more
doaj +1 more source