Results 71 to 80 of about 32,147 (209)

Aberrant glycosylation patterns as potential biomarkers for diagnosis and disease progression in bullous pemphigoid

Frontiers in Immunology
ObjectivesBullous pemphigoid (BP) is a prototypical autoimmune disease characterized by the production of autoantibodies against hemidesmosomal proteins BP180 and BP230.
Haijun Miao, Jundan Yang, Yaxing Bai, Shengxian Shen, Xia Li, Lixin Yue, Gang Wang, Erle Dang   +7 more
doaj   +1 more source

Enzymes for N-Glycan Branching and Their Genetic and Nongenetic Regulation in Cancer

Biomolecules, 2016
N-glycan, a fundamental and versatile protein modification in mammals, plays critical roles in various physiological and pathological events including cancer progression.
Yasuhiko Kizuka, Naoyuki Taniguchi
doaj   +1 more source

Holdfast adhesion in the kelp Alaria marginata: Cell wall polysaccharides and phenolics

Journal of Phycology, EarlyView.
Abstract Adhesion is a critical process in the survival of seaweeds, especially in wave‐swept environments. Kelp (Laminariales) sporophytes secrete adhesives from specialized rhizoid cells to anchor themselves to the substrate and withstand immense forces applied by waves.
Maisie R. Roy‐Musor, Christa Agoawike, A. Lacey Samuels, Patrick T. Martone   +3 more
wiley   +1 more source

Fucoidan Extracted from Undaria pinnatifida: Source for Nutraceuticals/Functional Foods

Marine Drugs, 2018
The importance of fucoidan as a functional ingredient in food, health products, and pharmaceutics is well-recognized due to its beneficial biological effects. Fucoidan is usually extracted from brown seaweeds, including Undaria pinnatifida.
Yu Zhao, Yizhou Zheng, Jie Wang, Shuyi Ma, Yiming Yu, William Lindsey White, Shiping Yang, Fan Yang, Jun Lu   +8 more
doaj   +1 more source

Revisiting the life cycle of Margalefidinium polykrikoides Group III

Journal of Phycology, EarlyView.
Abstract Dinoflagellates produce cysts as a strategy to withstand environmental stressors, with nutrient depletion generally considered a key trigger for cyst production. Resting cysts are thick‐walled, typically composed of one to several layers, and characterized by a prolonged dormancy period.
Eduardo Pérez‐Vega, Kenneth N. Mertens, Pjotr Meyvisch, Margaret R. Mulholland   +3 more
wiley   +1 more source

Holothurian Fucosylated Chondroitin Sulfate

Marine Drugs, 2014
Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within ...
Vitor H. Pomin
doaj   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

Glucose and fructose contributions to exogenous carbohydrate oxidation and performance at moderate altitude

The Journal of Physiology, EarlyView.
Abstract figure legend Co‐ingesting fructose with glucose increases exogenous carbohydrate oxidation at sea level, but its effect at altitude is unclear. This study compared glucose–fructose (GLU–FRU), glucose alone (GLU) and placebo during 120 min of running at 70% V̇O2max${{\dot{V}}_{{{{\mathrm{O}}}_2}{\mathrm{max}}}}$ at 2500 m in eight males.
Nicola C. Arjomandkhah, Andy J. King, Alex Griffiths, Roderick F. G. J. King, Douglas, J. Morrison, Thomas Preston, John P. O'Hara   +7 more
wiley   +1 more source

Molecular Simulations of Carbohydrates with a Fucose-Binding Burkholderia ambifaria Lectin Suggest Modulation by Surface Residues Outside the Fucose-Binding Pocket

Frontiers in Pharmacology, 2017
Burkholderia ambifaria is an opportunistic respiratory pathogen belonging to the Burkholderia cepacia complex, a collection of species responsible for the rapidly fatal cepacia syndrome in cystic fibrosis patients.
Tamir Dingjan, Anne Imberty, Serge Pérez, Elizabeth Yuriev, Paul A. Ramsland, Paul A. Ramsland, Paul A. Ramsland, Paul A. Ramsland   +7 more
doaj   +1 more source