Results 61 to 70 of about 60,769 (251)

Carbohydrate specificity of sea urchin sperm bindin: a cell surface lectin mediating sperm-egg adhesion. [PDF]

, 1982
We have examined the carbohydrate specificity of bindin, a sperm protein responsible for the adhesion of sea urchin sperm to eggs, by investigating the interaction of a number of polysaccharides and glycoconjugates with isolated bindin.
Glabe, CG, Grabel, LB, Rosen, SD, Vacquier, VD   +3 more
core  

Bioprospecting Ulleungdo‐isolated microalgae for carbon valorization and utilization

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The growing demand for renewable energy alternatives has intensified global interest in microalgae as versatile bioresources for carbon valorization and bioenergy production. Owing to their rapid growth and biochemical versatility, microalgae provide a sustainable route for converting captured carbon into bioenergy and high‐value products ...
Ha‐Neul Choi, Jeong‐Mi Do, Su‐Bin Park, Myeong‐Jun Gwon, Geum‐Sook Do, Ho‐Sung Yoon   +5 more
wiley   +1 more source

Enzymatic synthesis of l-fucose from l-fuculose using a fucose isomerase from Raoultella sp. and the biochemical and structural analyses of the enzyme

Biotechnology for Biofuels, 2019
Background l-Fucose is a rare sugar with potential uses in the pharmaceutical, cosmetic, and food industries. The enzymatic approach using l-fucose isomerase, which interconverts l-fucose and l-fuculose, can be an efficient way of producing l-fucose for ...
In Jung Kim, Do Hyoung Kim, Ki Hyun Nam, Kyoung Heon Kim   +3 more
doaj   +1 more source

A spectrophotometric study of the behavior of carbohydrates in seventy-nine per cent sulfuric acid [PDF]

, 1949
The spectral characteristics of solutions of eighteen representative monosaccharides in 79 per cent sulfuric acid have been determined for solutions maintained for 2 hours at 25° and 15 minutes at 100°.
Ikawa, Miyoshi, Niemann, Carl
core  

Human T cell glycosylation and implications on immune therapy for cancer [PDF]

, 2020
Glycosylation is an important post-translational modification, giving rise to a diverse and abundant repertoire of glycans on the cell surface, collectively known as the glycome.
Callewaert, Nico, De Bousser, Elien, Festjens, Nele, Meuris, Leander   +3 more
core   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Protein oxidation of fucose environments (POFE) reveals fucose–protein interactions

Chemical Science
POFE (Protein Oxidation of Fucose Environments) method utilizes proximity-based oxidative proteomics to decipher cellular fucosylated glycoprotein interactions.
Yixuan Xie, Siyu Chen, Michael Russelle Alvarez, Ying Sheng, Qiongyu Li, Emanual Maverakis, Carlito B. Lebrilla   +6 more
openaire   +4 more sources

L-Fucose treatment of FUT8-CDG

Molecular Genetics and Metabolism Reports, 2020
FUT8-CDG is a severe multisystem disorder caused by mutations in FUT8, encoding the α-1,6-fucosyltransferase. We report on dizygotic twins with FUT8-CDG presenting with dysmorphisms, failure to thrive, and respiratory abnormalities. Due to the severe phenotype, oral L-fucose supplementation was started.
Park, Julien H., Reunert, Janine, He, Miao, Mealer, Robert G., Noel, Maxence, Wada, Yoshinao, Grueneberg, Marianne, Horvath, Judit, Cummings, Richard D., Schwartz, Oliver, Marquardt, Thorsten   +10 more
openaire   +4 more sources

Changes in heparin- and lectin-binding activity of fibronectin in proliferative blood diseases

Біологічні студії, 2010
Fibronectin concentration, its heparin-binding activity and interaction with Lens Culinaris Agglutinin (LCA), Aleuria Aurantia Lectin (AAL) and Laburnum Anagyroides Agglutinin (LABA) in patients with erythremia and subleukemic myelosis were investigated.
A. O. Kulinich, A. I. Shevtsova, I. U. Pismenetskaya, A. S. Maslak, T. P. Nikolaenko-Kamyshova   +4 more
doaj   +1 more source

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

Journal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel, Tse Wen Chang, Carmay Lim   +2 more
wiley   +1 more source