Challenges in the enantioanalysis of fucose using stochastic and potentiometric microsensors
Fucose gained significant interest in the medical field since a large number of studies have been reported on the role of fucose – as tumor marker. Electrochemical enantioselective sensors based on monocrystalline diamond paste and carbon paste working ...
Iuliana Moldoveanu +4 more
doaj +1 more source
Fucose as a nutrient ligand for Dikarya and a building block of early diverging lineages
Fucose is a deoxyhexose sugar present and studied in mammals. The process of fucosylation has been the primary focus in studies relating to fucose in animals due to the presence of fucose in Lewis antigens.
Małgorzata Orłowska +3 more
doaj +1 more source
Exploring the diverse biological significance and roles of fucosylated oligosaccharides
Long since, carbohydrates were thought to be used just as an energy source and structural material. However, in recent years, with the emergence of the field of glycobiology and advances in glycomics, much has been learned about the biological role of ...
Burcu Pekdemir, Sercan Karav
doaj +1 more source
Targeting anticancer drug delivery to pancreatic cancer cells using a fucose-bound nanoparticle approach. [PDF]
Owing to its aggressiveness and the lack of effective therapies, pancreatic ductal adenocarcinoma has a dismal prognosis. New strategies to improve treatment and survival are therefore urgently required.
Makoto Yoshida +13 more
doaj +1 more source
Artificial Host‐Guest Recognition Directs Glycometabolically Engineered Macrophages to Tumors
Glycoengineered supramolecular macrophages (GSAR‐M) are developed using glycometabolic labeling for bioorthogonal host‐guest tumor targeting. This engineering approach unexpectedly enhances macrophage migration, phagocytosis, and pseudopodia formation. Consequently, GSAR‐M demonstrate robust tumor‐targeting specificity, effectively arrest tumor growth,
Zhiqing Yang +8 more
wiley +1 more source
Synthesis of Fucose Derivatives with Thiol Motifs towards Suicide Inhibition of Helicobacter pylori
The syntheses of six thiol-exhibiting monosaccharides towards suicide inhibition of Helicobacter pylori are reported. Blood group Antigen Binding Adhesin (BabA), a bacterial membrane-bound lectin, binds to human ABO and Lewis b blood group structures ...
Mark Reihill +3 more
doaj +1 more source
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun +7 more
wiley +1 more source
Fucose sensing regulates bacterial intestinal colonization.
The mammalian gastrointestinal tract provides a complex and competitive environment for the microbiota. Successful colonization by pathogens requires scavenging nutrients, sensing chemical signals, competing with the resident bacteria and precisely ...
Waldor, MK +6 more
core +2 more sources
Fucose content of keratan sulphates from bovine articular cartilage [PDF]
Alkaline-borohydride-reduced keratan sulphate chains were isolated from bovine articular cartilage (6-8-year-old animals). Nine keratan sulphate fractions of increasing molecular weight were prepared by gel-permeation chromatography on a calibrated ...
Nieduszynski, I A +4 more
core +4 more sources
(Semi)-Synthetic Fucosylated Chondroitin Sulfate Oligo- and Polysaccharides
Fucosylated chondroitin sulfate (fCS) is a glycosaminoglycan (GAG) polysaccharide with a unique structure, displaying a backbone composed of alternating N-acetyl-d-galactosamine (GalNAc) and d-glucuronic acid (GlcA) units on which l-fucose (Fuc) branches
Giulia Vessella +4 more
doaj +1 more source

