Results 81 to 90 of about 32,147 (209)

Galectin‐4: A Novel Mediator of Human Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 3, September 2026.
Galectin‐4 correlates with intervertebral disc degeneration, independent of age, sex, or underlying pathology. Functionally, it activates NF‐κB signaling and induces pro‐inflammatory and matrix‐degrading responses, with stronger effects in nucleus pulposus cells, identifying it as a novel molecular player in disc degeneration.
Christine Strauss, Daniel Djojic, Johannes Stadlmann, Josef Georg Grohs, Jürgen Alphonsus, Sebastian Schmidt, Sabine André, Katharina Margareta Pichler, Sara Savic‐Ivanovic, Melanie Cezanne, Mario Rothbauer, Reinhard Windhager, Stefan Toegel   +12 more
wiley   +1 more source

Understanding the Molecular Processes of Obesity and the Anti‐Obesity Properties of Bioactive Substances Found in Tea

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
ABSTRACT Obesity, a severe worldwide health concern, is characterized as an excessive deposit of fat in the human body. It has various ramifications that endanger human health and increase the financial expense. Obesity raises the risk of several illnesses, notably cardiovascular disease, NALFD, and diabetes, and has been associated with shorter ...
Sakhawat Riaz, Fan Wenni, Danish Kamal, Umber Mubeen, Abul Hassan, Arslan Ahmed, Munir Ahmed   +6 more
wiley   +1 more source

Commercially Exploited Seaweed Species in Africa: Occurrences, Chemical Composition, Current Value Chain and Opportunities for Value Addition

Reviews in Aquaculture, Volume 18, Issue 4, September 2026.
Commercially exploited seaweed species in Africa, their biochemical composition, current uses, and value chain are reviewed. Potential value‐addition of seaweed is suggested regionally in Africa amongst countries producing similar seaweed species. ABSTRACT Africa has a wide range of coastal environments that support a diverse array of seaweed species ...
Mondli Abednicko Masanabo, Marthe Jordbrekk Blikra, Trond Løvdal, Dagbjørn Skipnes, Morten Sivertsvik, Aditya Parmar, M. Naushad Emmambux   +6 more
wiley   +1 more source

Comparative Study of Fucose, Protein, Protein Bound Fucose and Protein Bound Hexose in Sera of Hyperprolactinemia Human Female and Healthy Female

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
This study was conducted in the specialized center of endocrinology and diabetic (AlKindy hospital from June 2004 to April 2005). Sera of 80 women (include 40 diagnosed Hyperprolactinemia (HPro) and 40 healthy women as control) were used to estimate ...
W.F. Al-Taie, M. A. Al-Iqabi
doaj  

O-Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2-O-methyl-L-selenofucopyranoside

Beilstein Journal of Organic Chemistry, 2016
Selenoglycosides are used as reactive glycosyl donors in the syntheses of oligosaccharides. In addition, such heavy atom analogs of natural glycosides are useful tools for structure determination of their lectin receptors using X-ray crystallography ...
Roman Sommer, Dirk Hauck, Annabelle Varrot, Anne Imberty, Markus Künzler, Alexander Titz   +5 more
doaj   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6380-6394, 30 August 2026.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza, Hyeonjun Yu, Jonghyun Jeong, Jung Cheul Shin, Woo Jung Kim, Sung‐Kwon Moon, Hoon Kim   +6 more
wiley   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, Volume 13, Issue 44, 7 August 2026.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Genetic‐Proteomic Integration Identifies Predictive Plasma Proteins for Multiple Sclerosis

Annals of Neurology, Volume 100, Issue 2, Page 268-281, August 2026.
Objective Multiple sclerosis (MS) develops after a prolonged preclinical phase. Identifying circulating biomarkers that capture this early biology can improve risk stratification and guide intervention. We aimed to identify plasma proteins driving MS susceptibility using large‐scale proteogenomic integration and to evaluate their prediagnostic ...
Yuan Ding, Dylan Hamitouche, Simon Thebault, Patrick Kearns, Ahmed Abdelhak, Adil Harroud   +5 more
wiley   +1 more source

Effects of Lactobacillus‐Mediated Functionalization of Dendrobium officinale Polysaccharides: A Study From Physicochemical Properties and Structural Changes to Anti‐Inflammatory Activity

eFood, Volume 7, Issue 4, August 2026.
Lactic acid bacteria (LAB) fermentation cleaves specific glycosidic bonds in Dendrobium officinale polysaccharides (DOPs), reducing molecular weight and enhancing anti‐inflammatory activity through regulation of inflammatory cytokines, oxidative stress, and intestinal barrier function.
Dingding Hong, Hui Ye, Xiaojun Huang
wiley   +1 more source

Keratan Sulfate: An Electroconductive Glycosaminoglycan at the Interface of Sensory Perception and Neural Signaling

Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.
Laboratory studies show KS has electroconductive properties with the ability to trap and transport protons in neurotransductive processes (Grotthuss proton shuttling). This maintains electrochemical gradients and fluxes at the neuronal cell surface in neural activation. Such processes are central to neuronal cell signaling and communication.
James Melrose
wiley   +1 more source