Results 81 to 90 of about 41,130 (245)
Journal of the Chinese Chemical Society, EarlyView.This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel +2 more
wiley +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen +2 more
wiley +1 more source
Ion Activation Methods for Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
Fucose is emerging as a wonder glycan for improving the success of hematopoietic stem cell (HSC) transplantation in bone marrow, with implications for a broad range of diseases especially those relating to blood. When the sugar is added to the surface of
Al-Amoodi, Asma +8 more
core +1 more source
Suppression of Allergic Contact Dermatitis by α-L-fucose [PDF]
, 1980 We observed that L-fucose could suppress the skin reaction of allergic contact dermatitis induced by dinitrochlorobenzene. This observation was ascertained by histological examination as well as by visual inspection. The degrees of the acanthosis and the
Shoji Hasegawa +5 more
core +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
Six Fucose-α(1−2) sugars and α-Fucose assigned in human brain using in vivo L-COSY
, 2015 A growing literature indicates that Fucose7α(1−2)7galactose sugars are implicated in the molecular mechanisms that underlie neuronal development, learning, and memory in the human brain.
Ramadan, Saadallah +3 more
core
Enzymes for N-Glycan Branching and Their Genetic and Nongenetic Regulation in Cancer
Biomolecules, 2016 N-glycan, a fundamental and versatile protein modification in mammals, plays critical roles in various physiological and pathological events including cancer progression.
Yasuhiko Kizuka, Naoyuki Taniguchi
doaj +1 more source
Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale Hemicelluloses are abundant carbohydrate components in plant cell walls. They play a crucial structural role in binding cellulose microfibrils, in addition to other biological functions. Their high structural variability directly influences their biological properties, making it important to establish a structure–function ...
Rania Benazza +3 more
wiley +1 more source
Journal of Baghdad College of Dentistry, 2014 Background: ?-L-Fucose is a methyl pentose sugar, had the ability to kill bacteria, controlling infection and normalize immune function. The objective of this study is to determine the effect of sulcular injection of fucose on rabbits periodontium ...
Chenar A Mohammad +2 more
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