Results 81 to 90 of about 61,412 (311)

Alleviation of Intestinal Inflammation by Oral Supplementation With 2-Fucosyllactose in Mice

Frontiers in Microbiology, 2019
Milk oligosaccharides exert a prebiotic action that contributes to the development of the infant gut microbiota during lactation. Given that milk oligosaccharides remain intact after passage through stomach and small intestine, they can potentially ...
Thomas Grabinger, Jesus Francisco Glaus Garzon, Martin Hausmann, Annelies Geirnaert, Christophe Lacroix, Thierry Hennet   +5 more
doaj   +1 more source

(Semi)-Synthetic Fucosylated Chondroitin Sulfate Oligo- and Polysaccharides

Marine Drugs, 2020
Fucosylated chondroitin sulfate (fCS) is a glycosaminoglycan (GAG) polysaccharide with a unique structure, displaying a backbone composed of alternating N-acetyl-d-galactosamine (GalNAc) and d-glucuronic acid (GlcA) units on which l-fucose (Fuc) branches
Giulia Vessella, Serena Traboni, Antonio Laezza, Alfonso Iadonisi, Emiliano Bedini   +4 more
doaj   +1 more source

Targeting anticancer drug delivery to pancreatic cancer cells using a fucose-bound nanoparticle approach. [PDF]

PLoS ONE, 2012
Owing to its aggressiveness and the lack of effective therapies, pancreatic ductal adenocarcinoma has a dismal prognosis. New strategies to improve treatment and survival are therefore urgently required.
Makoto Yoshida, Rishu Takimoto, Kazuyuki Murase, Yasushi Sato, Masahiro Hirakawa, Fumito Tamura, Tsutomu Sato, Satoshi Iyama, Takahiro Osuga, Koji Miyanishi, Kohichi Takada, Tsuyoshi Hayashi, Masayoshi Kobune, Junji Kato   +13 more
doaj   +1 more source

Comparative Genomics of Campylobacter fetus from Reptiles and Mammals Reveals Divergent Evolution in Host-Associated Lineages [PDF]

, 2016
Acknowledgments The authors like to thank Brian Brooks and John Devenish (Canadian Food Inspection Agency) for providing strains and valuable suggestions.Peer reviewedPublisher ...
Duim, Birgitta, Fitzgerald, Collette, Forbes, Ken J., Gilbert, Maarten J., Miller, William G., Méric, Guillaume, Sheppard, Samuel K., van der Graaf-van Bloois, Linda, Wagenaar, Jaap A., Yee, Emma, Zomer, Aldert L.   +10 more
core   +2 more sources

A Surface Plasmon Resonance‐Based Integrated Assay for Quantification and Glycosylation Characterization of Monoclonal Antibodies in Crude Heterogeneous Samples

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The rise in cancer, autoimmune, inflammatory, and infectious diseases in recent decades has led to a surge in the development of monoclonal antibodies (mAbs) therapies, now the most widely used family of biologics. To meet the growing global demand, biopharmaceutical industries are intensifying their production processes.
Ilona Metayer, Catherine Forest‐Nault, Julie Guimond, Simon Joubert, Olivier Henry, Yves Durocher, Gregory De Crescenzo, Jimmy Gaudreault   +7 more
wiley   +1 more source

Characterization of the Exopolysaccharide Produced by Salipiger mucosus A3T, a Halophilic Species Belonging to the Alphaproteobacteria, Isolated on the Spanish Mediterranean Seaboard

Marine Drugs, 2010
We have studied the exopolysaccharide produced by the type strain of Salipiger mucosus, a species of halophilic, EPS-producing (exopolysaccharide-producing) bacterium belonging to the Alphaproteobacteria.
Victoria Béjar, Emilia Quesada, María C. Urdaci, Philippe Bressollier, Richard Tallon, Juan Antonio Mata, Inmaculada Llamas   +6 more
doaj   +1 more source

Genetic Locus Required for Antigenic Maturation of \u3cem\u3eRhizobium etli\u3c/em\u3e CE3 Lipopolysaccharide [PDF]

, 2001
Rhizobium etli modifies lipopolysaccharide (LPS) structure in response to environmental signals, such as low pH and anthocyanins. These LPS modifications result in the loss of reactivity with certain monoclonal antibodies.
Box, Jodie M, Carlson, Russell W, Duelli, Dominik M, Kumar Kolli, V.S., Noel, K. Dale, Tobin, Andrea   +5 more
core   +1 more source

Metabolomic profiles are gender, disease and time specific in the interleukin-10 gene-deficient mouse model of inflammatory bowel disease. [PDF]

, 2013
Metabolomic profiling can be used to study disease-induced changes in inflammatory bowel diseases (IBD). The aim of this study was to investigate the difference in the metabolomic profile of males and females as they developed IBD.
Churchill, Thomas A, Doyle, Jason, Fedorak, Richard N, Foshaug, Rae R, Slupsky, Carolyn M, Sydora, Beate C, Tso, Victor K   +6 more
core   +2 more sources

Genetic Divergence and Antibody Expression Influence the N‐Glycomes of CHO‐K1 and CHO‐S Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT While Chinese hamster ovary (CHO) cells continue to be the workhorse of recombinant therapeutic protein production, decades of genetic divergence in the industrially relevant CHO‐K1 and CHO‐S cell lines, are likely to have resulted in differing glycosylation capabilities. Glycosylation can influence the efficacy, serum half‐life, and safety of
Roberto Donini, Pat Blundell, Richard J. Pleass, Dongli Lu, Anne Dell, Cleo Kontoravdi, Stuart M. Haslam   +6 more
wiley   +1 more source

The effect of intracrevicular injection of fucose on serum interlukine -1beta and tumor necrosis factor alpha

Journal of Baghdad College of Dentistry, 2014
Background: ?-L-Fucose is a methyl pentose sugar, had the ability to kill bacteria, controlling infection and normalize immune function. The objective of this study is to determine the effect of sulcular injection of fucose on rabbits periodontium ...
Chenar A Mohammad, Khlood A Al-Safi , Bakhtiar A Ahmed   +2 more
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