Interplay of the ENS and Microbiota With Murine Gut Epithelium‐Derived Organoids in Aging
A gut organoid model was developed to study the impact of age‐related changes of the enteric nervous system (ENS) and microbiome on the integrity and trophic capacity of the intestinal epithelial barrier. Organoids reflected in vivo aging features, including altered epithelial integrity and changes in acetylcholine‐related enzyme activity.
Tinh Thi Nguyen +12 more
wiley +1 more source
Expression and characterization of the human fucosyltransferase V [PDF]
Zusammenfassung Im Rahmen dieser Arbeit sollten Studien zur rekombinanten Expression der humanen Fucosyltransferase V durchgeführt werden. Die Fucosyltransferase V katalysiert den Transfer von L-Fucopyranose von GDP-Fucose zum Akzeptor- Substrat N ...
Münster, Jan
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Effects of Arabidopsis wall associated kinase mutations on ESMERALDA1 and elicitor induced ROS.
Angiosperm cell adhesion is dependent on interactions between pectin polysaccharides which make up a significant portion of the plant cell wall. Cell adhesion in Arabidopsis may also be regulated through a pectin-related signaling cascade mediated by a ...
Bruce D Kohorn +4 more
doaj +1 more source
Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska +2 more
wiley +1 more source
Molecular Characterization of Secretor Typeα(1, 2)-fucosyltransferase Gene Deficiency in the Philippine Population [PDF]
[[abstract]] We analyzed the seven mutations which are responsible for the deficiency of the secretor type α(1,2)-fucosyltransferase gene product, Se enzyme, in the Philippine population. One hundred and one unrelated Filipinos in Taiwan were studied.
Peng, C. T. ; Tsai, C. H. ; Lin, T. P. ; Perng, L. I. ; Kao, M. C. ; Yang, T. Y. ; Wang, Nancy M. ; Liu, T. C. ; Lin, S. F. ; Chang, J. G.
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Development, Production, and Application of Recombinant Yeast Biocatalysts in Organic Synthesis
The use of biocatalysts from yeast strains in organic synthesis is well established and covers a broad range of reaction classes. A particularly interesting reaction class is the regio- and stereospecific attachment of sugar moieties (i.e ...
Roland Wohlgemuth
doaj +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Co-purification of the Lewis Blood group N-acetylglucosaminide α1→4 fucosyltransferase and an N-acetylglucosaminide α1→3 fucosyltransferase from human milk [PDF]
The Lewis blood group-specified N-acetylglucosaminide α1 →4 fucosyltransferase and an N-acetylglucosaminide α1 →3 fucosyltransferase have been co-purified over 500,000-fold from human milk by affinity chromatography on GDP-hexanolamine agarose.
Monnom, Dominique +4 more
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ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA [PDF]
Adhesion of circulating leukocytes to the vascular endothelium during inflammation is mediated in part by their interaction with the endothellal-leukocyte adhesion molecule ELAM-1.
Robert D. Larsen +11 more
core +1 more source
What you have to know about Human Milk Oligosaccharides
Human Milk Oligosaccharides (HMOs), the third most important solid components of BM (the first and the second being lactose and lipids respectively), are a highly variable family of unconjugated glycans related to many pathophysiological short- and long ...
Vassilios Fanos +3 more
doaj +1 more source

