Results 61 to 70 of about 13,568 (269)

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts

Nature Communications, 2017
The role of O-glycosylation in the malaria life cycle is largely unknown. Here, the authors identify a Plasmodium protein O-fucosyltransferase and show that it is important for normal trafficking of a subset of surface proteins, particularly CSP and TRAP,
Sash Lopaticki, Annie S. P. Yang, Alan John, Nichollas E. Scott, James P. Lingford, Matthew T. O’Neill, Sara M. Erickson, Nicole C. McKenzie, Charlie Jennison, Lachlan W. Whitehead, Donna N. Douglas, Norman M. Kneteman, Ethan D. Goddard-Borger, Justin A. Boddey   +13 more
doaj   +1 more source

Clinical significance of the fucosyltransferase 2 (FUT2) secretor status in children hospitalized with acute gastroenteritis in Taiwan

Journal of the Formosan Medical Association, 2021
Background/Purpose: The FUT2 gene is a histo-blood group antigen (HBGA) that determines the susceptibility to Norovirus (NoV) infection. This study investigated the clinical significance of the FUT2 gene profile and HBGA expression in NoV infection ...
Hsin-Yeh Lin, Hung-Hsiang Lai, Ying Fang Elaine Chen, Hsun-Ching Chao, Chi-Neu Tsai, Yi-Jung Chang, Shih-Yen Chen   +6 more
doaj   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

A fucosyltransferase in teratocarcinoma stem cells Decreased activity accompanying differentiation to parietal endoderm cells [PDF]

, 1983
Teratocarcinoma stem cell F9 expressed a potent fucosyltransferase activity acting on asialofetuin. A majority of the product was susceptible to α-L-fucosidase I from almond emulsin, indicating that the linkage formed was mainly Fucα1 → 3GlcNAc.
Takashi Muramatsu, Hisako Muramatsu, Muramatsu, Takashi, Muramatsu, Hisako   +3 more
core   +1 more source

Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal, Anuradha Bankar, Vinicio A. de Jesus Perez   +2 more
wiley   +1 more source

Purification of human milk fucosyltransferase [PDF]

, 1976
The enzyme has been purified from skimmed milk concentrated on an Amicon PM 10 membrane and desalted on a Sephadex G 25 column equilibrated with 0.02 M MOPS buffer pH 7.4 contaning 10 mM MgCl2.
Dolmans, Marcel, Leonis, José, Petiau-de Vries, Ghislaine, Vandenbroucke, Anne Thérèse   +3 more
core  

In silico identification and in vivo validation of fucosyltransferase in some insect species [PDF]

, 2023
Fukoziltransferazlar (FucT) tip II trans-membran golgi yerleşik proteinlerdir ve ?-L-fukozun GDP-Fuk'tan N- ve O-bağlı glikanlara, serbest oligosakkaritlere, lipidlere veya doğrudan proteinlere transferini (fukozilasyon) katalize ederler. Fukozilasyonlar,
Oylum, Sadiye
core  

Human Milk Bioactive Compounds and Psychomotor Outcomes in Infants and Children: A Systematic Review

Molecular Nutrition &Food Research, Volume 70, Issue 14, 29 July 2026.
In our review, we assess the role of HM fatty acids, oligosaccharides, proteins, and carotenoids, on psychomotor development in children up to 18 years. Findings suggest that HM BCs, particularly n‐3 PUFAs and fucosylated HMOs, might contribute to a favorable psychomotor development in infancy, preschool age, and school age.
Lara Huber, Eduard Flores Ventura, Regina Ensenauer, Daria Guseva   +3 more
wiley   +1 more source

L-Fucose treatment of FUT8-CDG

Molecular Genetics and Metabolism Reports, 2020
FUT8-CDG is a severe multisystem disorder caused by mutations in FUT8, encoding the α-1,6-fucosyltransferase. We report on dizygotic twins with FUT8-CDG presenting with dysmorphisms, failure to thrive, and respiratory abnormalities.
Julien H. Park, Janine Reunert, Miao He, Robert G. Mealer, Maxence Noel, Yoshinao Wada, Marianne Grüneberg, Judit Horváth, Richard D. Cummings, Oliver Schwartz, Thorsten Marquardt   +10 more
doaj   +1 more source