Results 41 to 50 of about 12,774 (221)

AtFUT4 and AtFUT6 Are Arabinofuranose-Specific Fucosyltransferases [PDF]

Frontiers in Plant Science, 2021
The bulk of plant biomass is comprised of plant cell walls, which are complex polymeric networks, composed of diverse polysaccharides, proteins, polyphenolics, and hydroxyproline-rich glycoproteins (HRGPs). Glycosyltransferases (GTs) work together to synthesize the saccharide components of the plant cell wall.
Maria J. Soto, Maria J. Soto, Maria J. Soto, Pradeep Kumar Prabhakar, Pradeep Kumar Prabhakar, Pradeep Kumar Prabhakar, Hsin-Tzu Wang, Hsin-Tzu Wang, Hsin-Tzu Wang, Jason Backe, Jason Backe, Digantkumar Chapla, Digantkumar Chapla, Max Bartetzko, Ian M. Black, Parastoo Azadi, Parastoo Azadi, Maria J. Peña, Maria J. Peña, Fabian Pfrengle, Fabian Pfrengle, Kelley W. Moremen, Kelley W. Moremen, Breeanna R. Urbanowicz, Breeanna R. Urbanowicz, Breeanna R. Urbanowicz, Michael G. Hahn, Michael G. Hahn, Michael G. Hahn   +28 more
openaire   +6 more sources

The one-pot multienzyme (OPME) synthesis of human blood group H antigens and a human milk oligosaccharide (HMOS) with highly active Thermosynechococcus elongatus α1–2-fucosyltransferase [PDF]

, 2016
A novel α1-2-fucosyltransferase from Thermosynechococcus elongatus BP-1 (Te2FT) with high fucosyltransferase activity and low donor hydrolysis activity was discovered and characterized.
Liu, Bin, Chen, Xi, Shah, Ishita M, Li, Yanhong, Wu, Yijing, Zeng, Jie, Yu, Hai, Mills, David A, Zhao, Chao   +8 more
core   +1 more source

Estimation of Lewis Blood Group Status by Fluorescence Melting Curve Analysis in Simultaneous Genotyping of c.385A>T and Fusion Gene in FUT2 and c.59T>G and c.314C>T in FUT3

Diagnostics, 2023
Lewis blood group status is determined by two fucosyltransferase activities: those of FUT2-encoded fucosyltransferase (Se enzyme) and FUT3-encoded fucosyltransferase (Le enzyme).
Mikiko Soejima, Yoshiro Koda
doaj   +1 more source

Determination of α1–6-fucosyltransferase activity.

, 2014
Recombinant FLAG-tagged Sf9 FUT8 was produced using the baculovirus-Sf9 cell system and purified using anti-FLAG M2 affinity gel. The fucosyltransferase activity of the recombinant protein was tested with GDP-[14C]-L-fucose, as substrate, after two days (
François Monjaret (647590), Sylvie Juliant (647588), Marie-Luce Violet (647592), Anne Harduin-Lepers (647589), Martine Duonor-Cérutti (647595), Annick Ozil (647594), Béatrice Catieau (647591), Pierre Cérutti (647593)   +7 more
core   +1 more source

Glycosyltransferases: glycoengineers in human milk oligosaccharide synthesis and manufacturing

Frontiers in Molecular Biosciences
Human milk oligosaccharides (HMOs) are a diverse group of complex carbohydrates that play crucial roles in infant health, promoting a beneficial gut microbiota, modulating immune responses, and protecting against pathogens.
Alanna S. Slater, Alanna S. Slater, Andrew G. McDonald, Rita M. Hickey, Gavin P. Davey   +4 more
doaj   +1 more source

Evolution of Fucosyltransferase Genes in Vertebrates [PDF]

Journal of Biological Chemistry, 1997
Cloning and expression of chimpanzee FUT3, FUT5, and FUT6 genes confirmed the hypothesis that the gene duplications at the origin of the present human cluster of genes occurred between: (i) the great mammalian radiation 80 million years ago and (ii) the separation of man and chimpanzee 10 million years ago. The phylogeny of fucosyltransferase genes was
M, Costache, P A, Apoil, A, Cailleau, A, Elmgren, G, Larson, S, Henry, A, Blancher, D, Iordachescu, R, Oriol, R, Mollicone   +9 more
openaire   +2 more sources

Cytogenetics, conserved synteny and evolution of chicken fucosyltransferase genes compared to human

, 2003
Fucosyltransferases appeared early in evolution, since they are present from bacteria to primates and the genes are well conserved. The aim of this work was to study these genes in the bird group, which is particularly attractive for the comprehension of
Zoorob, R., Oriol, R., Candelier, J.J., Mollicone, R., Bernheim, A., Crooijmans, R.P.M.A., Coullin, P., Groenen, M.A.M., Fillon, V., Adrien-Dehais, C.   +9 more
core   +1 more source

Fucosyltransferase 2 inhibitors: Identification via docking and STD-NMR studies.

PLoS ONE, 2021
Fucosyltransferase 2 (FUT2) catalyzes the biosynthesis of A, B, and H antigens and other important glycans, such as (Sialyl Lewisx) sLex, and (Sialyl Lewisy) sLey.
Humaira Zafar, Muhammad Atif, Atia-Tul-Wahab, M Iqbal Choudhary   +3 more
doaj   +1 more source

Purification and Some Properties of Fucosyltransferase in Human Parotid Saliva

, 1987
Fucosyltransferase was purified from human parotid saliva by affinity chromatography on GDP-hexanolamine Sepharose, followed by chromatofocusing on PBE 94 exchanger gel. The purified enzyme had the N-acetylglucosaminide α1→4, the N-acetylglucosaminide α1→
T. Takeshita, H. Tamagawa, E. Inoshita, S. Shizukuishi, M. Takagaki, A. Tsunemitsu   +5 more
core   +1 more source

Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.

PLoS Genetics, 2010
Over half of all proteins are glycosylated, and alterations in glycosylation have been observed in numerous physiological and pathological processes.
Gordan Lauc, Abdelkader Essafi, Jennifer E Huffman, Caroline Hayward, Ana Knežević, Jayesh J Kattla, Ozren Polašek, Olga Gornik, Veronique Vitart, Jodie L Abrahams, Maja Pučić, Mislav Novokmet, Irma Redžić, Susan Campbell, Sarah H Wild, Fran Borovečki, Wei Wang, Ivana Kolčić, Lina Zgaga, Ulf Gyllensten, James F Wilson, Alan F Wright, Nicholas D Hastie, Harry Campbell, Pauline M Rudd, Igor Rudan   +25 more
doaj   +1 more source