Substrate Specificity of Fucosyltransferase Purified from Human Parotid Saliva [PDF]
, 1987 The purified fucosyltransferase from human parotid saliva was shown to transfer fucose from GDP-fucose onto the oligosaccharide chains containing the Galβl→3GlcNAc or Gal β 1→4GlcNAc/Glc sequences.
H. Tamagawa +4 more
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The Function of Fucosylation in Progression of Lung Cancer
Frontiers in Oncology, 2018 Lung cancer is a disease that influences human health and has become a leading cause of cancer mortality worldwide. However, it is frequently diagnosed at the advanced stage.
Liyuan Jia +9 more
doaj +1 more source
Diagnostics, 2023 Lewis blood group status is determined by two fucosyltransferase activities: those of FUT2-encoded fucosyltransferase (Se enzyme) and FUT3-encoded fucosyltransferase (Le enzyme).
Mikiko Soejima, Yoshiro Koda
doaj +1 more source
A new superfamily of protein-O-fucosyltransferases, 2-fucosyltransferases, and 6-fucosyltransferases: phylogeny and identification of conserved peptide motifs [PDF]
Glycobiology, 2003 The presence of three conserved peptide motifs shared by alpha2-fucosyltransferases, alpha6-fucosyltransferases, the protein-O-fucosyltransferase family 1 (POFUT1) and a newly identified protein-O-fucosyltransferase family 2 (POFUT2), together with evidence that the present genes encoding for these enzymes have originated from a common ancestor by ...
Ivan, Martinez-Duncker +4 more
openaire +2 more sources
O-Glycosylation of thrombospondin type 1 repeats : identification and characterisation of β1,3-glucosyltransferase [PDF]
, 2008 Rare types of protein glycosylation often occur in a domain-specific manner required for important biological functions (Okajima et al. 2008). O-linked fucosylation, where the fucose is linked directly to the hydroxyl groups of serine or threonine ...
Keusch, Krisztina
core +1 more source
FUT1 variants responsible for Bombay or para-Bombay phenotypes in a database
Scientific Reports, 2023 Rare individuals with Bombay and para-Bombay phenotypes lack or have weak expression of the ABO(H) antigens on surface of red blood cells due to no or very weak H-type α(1,2)fucosyltransferase activity encoded by FUT1.
Mikiko Soejima, Yoshiro Koda
doaj +1 more source
The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA [PDF]
, 2017 Plant development requires coordination among complex signaling networks to enhance the plant's adaptation to changing environments. DELLAs, transcription regulators originally identified as repressors of phytohormone gibberellin signaling, play a ...
Rodolfo Zentella +10 more
openalex +3 more sources
AtFUT4 and AtFUT6 Are Arabinofuranose-Specific Fucosyltransferases [PDF]
Frontiers in Plant Science, 2021 The bulk of plant biomass is comprised of plant cell walls, which are complex polymeric networks, composed of diverse polysaccharides, proteins, polyphenolics, and hydroxyproline-rich glycoproteins (HRGPs). Glycosyltransferases (GTs) work together to synthesize the saccharide components of the plant cell wall.
Maria J. Soto +28 more
openaire +6 more sources
Fucosyltransferase 2: A Genetic Risk Factor for Intestinal Diseases
Frontiers in Microbiology, 2022 The fucosyltransferase 2 gene (FUT2) mediates the synthesis of histoblood group antigens (HBGA) that occur in vivo from multiple organs, particularly on the surface of intestinal epithelial cells and body fluids.
Mingyang Hu +5 more
doaj +1 more source
Fucosyltransferases: structure/function studies [PDF]
Glycobiology, 2001 Alpha3-fucosyltransferases (alpha3-FucTs) catalyze the final step in the synthesis of a range of important glycoconjugates that function in cell adhesion and lymphocyte recirculation. Six members of this family of enzymes have been cloned from the human genome, and their expression pattern has been shown to be highly regulated. Each enzyme has a unique
T, de Vries +3 more
openaire +2 more sources