Separation of Fucosyltransferase and Endogenous Acceptors of Fucose from Human Parotid Saliva [PDF]
, 1977 Using gel filtration on Sephadex G-100 and column chromatography on CM-cellulose, fractions containing either endogenous acceptor of L-fucose or fucosyltransferase were obtained from human parotid saliva.
Iwasaki, E. +11 more
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Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment [PDF]
Cytotherapy, 2014 Background aims: Advantages associated with the use of cord blood (CB) transplantation include the availability of cryopreserved units, ethnic diversity and lower incidence of graft-versus-host disease compared with bone marrow or mobilized peripheral blood. However, poor engraftment remains a major obstacle.
Robinson, Simon N +20 more
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مجله دانشگاه علوم پزشکی گرگان, 2021 Background and Objective: Colorectal cancer is one of the most common cancers and considered to be leading causes of cancer death in the world. One of the problems with this type of cancer is its inability to be detected in early stage.
Roya Abbasinatajomrani +3 more
doaj
Microbial Cell Factories, 2021 Background 2′-fucosyllactose (2′-FL) is one of the most abundant oligosaccharides in human milk. It constitutes an authorized functional additive to improve infant nutrition and health in manufactured infant formulations.
Mingyuan Xu +4 more
doaj +1 more source
A new superfamily of protein-O-fucosyltransferases, 2-fucosyltransferases, and 6-fucosyltransferases: phylogeny and identification of conserved peptide motifs [PDF]
Glycobiology, 2003 The presence of three conserved peptide motifs shared by alpha2-fucosyltransferases, alpha6-fucosyltransferases, the protein-O-fucosyltransferase family 1 (POFUT1) and a newly identified protein-O-fucosyltransferase family 2 (POFUT2), together with evidence that the present genes encoding for these enzymes have originated from a common ancestor by ...
Ivan, Martinez-Duncker +4 more
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Enzymatic Synthesis of a Fluorogenic Reporter Substrate and a High-Throughput Assay for Fucosyltransferase VIII Provide a Toolkit to Probe and Inhibit Core Fucosylation [PDF]
, 2019 We report a straight-forward enzymatic synthesis of the 4-methylumbelliferyl glycoside of a complex-type oligosaccharide substrate for core-fucosylation.
David, Kwan +3 more
core +1 more source
The Function of Fucosylation in Progression of Lung Cancer
Frontiers in Oncology, 2018 Lung cancer is a disease that influences human health and has become a leading cause of cancer mortality worldwide. However, it is frequently diagnosed at the advanced stage.
Liyuan Jia +9 more
doaj +1 more source
FUT1 variants responsible for Bombay or para-Bombay phenotypes in a database
Scientific Reports, 2023 Rare individuals with Bombay and para-Bombay phenotypes lack or have weak expression of the ABO(H) antigens on surface of red blood cells due to no or very weak H-type α(1,2)fucosyltransferase activity encoded by FUT1.
Mikiko Soejima, Yoshiro Koda
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Fucosyltransferase 2: A Genetic Risk Factor for Intestinal Diseases
Frontiers in Microbiology, 2022 The fucosyltransferase 2 gene (FUT2) mediates the synthesis of histoblood group antigens (HBGA) that occur in vivo from multiple organs, particularly on the surface of intestinal epithelial cells and body fluids.
Mingyang Hu +5 more
doaj +1 more source
Fucosyltransferases: structure/function studies [PDF]
Glycobiology, 2001 Alpha3-fucosyltransferases (alpha3-FucTs) catalyze the final step in the synthesis of a range of important glycoconjugates that function in cell adhesion and lymphocyte recirculation. Six members of this family of enzymes have been cloned from the human genome, and their expression pattern has been shown to be highly regulated. Each enzyme has a unique
T, de Vries +3 more
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