Results 21 to 30 of about 13,568 (269)
The Clinical Utility of Biochemical Biomarkers in Colorectal Cancer [PDF]
Middle East Journal of CancerColorectal cancer (CRC) ranks as the third most prevalent cancer worldwide and is a leading cause of cancer-related mortality. Since many colon cancers present no significant clinical symptoms, identifying new biomarkers or a set of biological indicators
Durdi Qujeq +5 more
doaj +1 more source
Structural insights into mechanism and specificity of the plant protein O-fucosyltransferase SPINDLY
Nature Communications, 2022 Arabidopsis SPINDLY (SPY) is a nucleocytoplasmic protein O-fucosyltransferase. Here, the authors present a crystal structure of Arabidopsis SPY/GDP complex, reveal SPY’s substrate recognition and enzyme mechanism, and provide insights into the glycan ...
Li Zhu +5 more
doaj +1 more source
Fucosyltransferase activities in human lymphocytes and granulocytes Blood group H-gene-specified α-2-L-fucosyltransferase is a discriminatory marker of peripheral blood lymphocytes [PDF]
, 1983 Human lymphocytes and granulocytes were examined for blood group H-gene-specified α-2-L-fucosyl-transferase, α-3-L-fucosyltransferase and blood group Le-gene-specified α-4-L-fucosyltransferase.
Ball, M.Geraldine +5 more
core +1 more source
Determination of α1–6-fucosyltransferase activity. [PDF]
, 2014 Recombinant FLAG-tagged Sf9 FUT8 was produced using the baculovirus-Sf9 cell system and purified using anti-FLAG M2 affinity gel. The fucosyltransferase activity of the recombinant protein was tested with GDP-[14C]-L-fucose, as substrate, after two days (
François Monjaret (647590) +7 more
core +1 more source
FUT8 Alpha-(1,6)-Fucosyltransferase in Cancer [PDF]
, 2021 Aberrant glycosylation is a universal feature of cancer cells that can impact all steps in tumour progression from malignant transformation to metastasis and immune evasion. One key change in tumour glycosylation is altered core fucosylation.
Jennifer Munkley +3 more
core +4 more sources
Survey and characterization of nonfunctional alleles of FUT2 in a database
Scientific Reports, 2021 The expression of ABO antigens in human saliva is regulated by the FUT2 gene, which encodes a secretor type α(1,2)fucosyltransferase. Secretors express ABO substrates in saliva and non-secretors do not. Secretor status is an object of concern, especially
Mikiko Soejima, Yoshiro Koda
doaj +1 more source
Human platelets release α-6-L-fucosyltransferase upon activation [PDF]
, 1989 Previously we have shown that human platelets release α-6-L-fucosyltransferase (EC 2.4.1.68) during coagulation of blood [(1987) Glycoconjugate J. 4, 43–49]. Here we report that agonists which induce platelet aggregation bring about release of the enzyme.
Kościelak, J. +7 more
core +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2021 Background and Objective: Colorectal cancer is one of the most common cancers and considered to be leading causes of cancer death in the world. One of the problems with this type of cancer is its inability to be detected in early stage.
Roya Abbasinatajomrani +3 more
doaj
Microbial Cell Factories, 2021 Background 2′-fucosyllactose (2′-FL) is one of the most abundant oligosaccharides in human milk. It constitutes an authorized functional additive to improve infant nutrition and health in manufactured infant formulations.
Mingyuan Xu +4 more
doaj +1 more source
Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment [PDF]
Cytotherapy, 2014 Background aims: Advantages associated with the use of cord blood (CB) transplantation include the availability of cryopreserved units, ethnic diversity and lower incidence of graft-versus-host disease compared with bone marrow or mobilized peripheral blood. However, poor engraftment remains a major obstacle.
Robinson, Simon N +20 more
openaire +2 more sources