Results 51 to 60 of about 13,568 (269)

The Cytoplasmic Tail of α1,2-Fucosyltransferase Contains a Sequence for Golgi Localization [PDF]

open access: yes, 2001
C1 - Journal Articles RefereedThe Golgi apparatus has a central role in the glycosylation of proteins and lipids. There is a sequential addition of carbohydrates by glycosyltransferases that are distributed within the Golgi in the order in which the ...
Taylor, SG   +4 more
core   +1 more source

Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants

open access: yesmSphere
Cellular adaptations to change often involve post-translational modifications of nuclear and cytoplasmic proteins. An example found in protists and plants is the modification of serine and threonine residues of dozens to hundreds of nucleocytoplasmic ...
Megna Tiwari   +11 more
doaj   +1 more source

α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish

open access: yesCells, 2022
Glycosylation is an important mechanism regulating various biological processes, including intercellular signaling and adhesion. α-1,6-fucosyltransferase (Fut8) belongs to a family of enzymes that determine the terminal structure of glycans.
Nozomi Hayashiji   +7 more
doaj   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

open access: yesAnimal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen   +7 more
wiley   +1 more source

Helicobacter hepaticus Hh0072 gene encodes a novel α1-3-fucosyltransferase belonging to CAZy GT11 family [PDF]

open access: yes, 2010
Lewis x (Lex) and sialyl Lewis x (SLex)-containing glycans play important roles in numerous physiological and pathological processes. The key enzyme for the final step formation of these Lewis antigens is α1-3-fucosyltransferase. Here we report molecular
Huang, Shengshu   +10 more
core   +1 more source

The alteration and role of glycoconjugates in Alzheimer’s disease

open access: yesFrontiers in Aging Neuroscience
Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder characterized by abnormal protein deposition. With an alarming 30 million people affected worldwide, AD poses a significant public health concern.
Yue Kang, Qian Zhang, Silu Xu, Yue Yu
doaj   +1 more source

Fucosyltransferases in Schistosoma mansoni development [PDF]

open access: yesGlycobiology, 2001
Glycoconjugate-bound fucose, abundant in the parasite Schistosoma mansoni, has been found in the form of Fucalpha1,3GlcNAc, Fucalpha1,2Fuc, Fucalpha1,6GlcNAc, and perhaps Fucalpha1,4GlcNAc linkages. Here we quantify fucosyltransferase activities in three developmental stages of S. mansoni.
E T, Marques   +5 more
openaire   +2 more sources

Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg   +2 more
wiley   +1 more source

Fucosyltransferase 8 (FUT8) and core fucose expression in oxidative stress response.

open access: yesPLoS ONE, 2023
GlycoMaple is a new tool to predict glycan structures based on the expression levels of 950 genes encoding glycan biosynthesis-related enzymes and proteins using RNA-seq data.
Yuki M Kyunai   +4 more
doaj   +2 more sources

FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression

open access: yesCommunications Biology, 2021
Puan and San Luis et al. find that FUT6, encoding a fucosyltransferase, is required for the “rolling” behavior of certain white blood cells that enables them to move from blood vessels to tissues.
Kia Joo Puan   +19 more
doaj   +1 more source

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