Results 101 to 110 of about 5,422 (250)
Targeting Selectins and Their Ligands in Cancer
Aberrant glycosylation is a hallmark of cancer cells with increased evidence pointing to a role in tumor progression. In particular, aberrant sialylation of glycoproteins and glycolipids have been linked to increased immune cell evasion, drug evasion ...
Alessandro eNatoni+3 more
doaj +1 more source
The sweet branch of metabolic engineering: cherry-picking the low-hanging sugary fruits [PDF]
In the first science review on the then nascent Metabolic Engineering field in 1991, Dr. James E. Bailey described how improving erythropoietin (EPO) glycosylation can be achieved via metabolic engineering of Chinese hamster ovary (CHO) cells.
Rachel Chen
core +1 more source
A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy. [PDF]
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Blank, Dennis+18 more
core +2 more sources
A humanized cancer‐specific anti‐podoplanin monoclonal antibody humPMab‐117 exerts antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity against human tumor cells. In the xenograft tumor models, humPMab‐117 demonstrated strong antitumor efficacy.
Tomohiro Tanaka+5 more
wiley +1 more source
The mucus layer in the gastrointestinal (GI) tract is considered to be the first line of defense to the external environment. Alteration in mucus components has been reported to occur during intestinal nematode infection in ruminants, but the role of ...
Rinaldi Manuela+8 more
doaj +1 more source
α1,3Fucosyltransferase VI is expressed in HepG2 cells and codistributed with β1,4galactosyltransferase I in the Golgi apparatus and monensin-induced swollen vesicles [PDF]
The major α1,3fucosyltransferase activity in plasma, liver, and kidney is related to fucosyltransferase VI which is encoded by the FUT6 gene. Here we demonstrate the presence of α1,3fucosyltransferase VI (α3-FucT VI) in the human HepG2 hepatoma cell line
Berger, Eric G.+3 more
core
Clinical Factors Affecting the Quality of Life of Women With Endometriosis
ABSTRACT Aim The study aimed to analyse selected clinical data affecting the quality of life of women with endometriosis. Design A cross‐sectional study. Method The study was conducted in 2020–2022 among 425 women with endometriosis receiving health care. A diagnostic survey method with a questionnaire technique was used.
Agnieszka Bień+6 more
wiley +1 more source
Fucosyltransferase 1 Mediates Angiogenesis in Rheumatoid Arthritis [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108009/1/art38648 ...
Amin+45 more
core +1 more source
B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen [PDF]
Analysis of non-Gal antibody induced after pig-to-baboon cardiac xenotransplantation identified the glycan produced by porcine beta-1,4-N-acetyl-galactosaminyltransferase 2 (B4GALNT2) as an immunogenic xenotransplantation antigen.
Ahmad-Villiers, S+3 more
core +1 more source
N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death. [PDF]
APO2L/TRAIL (TNF-related apoptosis-inducing ligand) induces death of tumor cells through two agonist receptors, TRAIL-R1 and TRAIL-R2. We demonstrate here that N-linked glycosylation (N-glyc) plays also an important regulatory role for TRAIL-R1-mediated ...
A Ashkenazi+59 more
core +2 more sources