Results 81 to 90 of about 3,115 (208)

N-Glycomic and Transcriptomic Changes Associated with CDX1 mRNA Expression in Colorectal Cancer Cell Lines

Cells, 2019
The caudal-related homeobox protein 1 (CDX1) is a transcription factor, which is important in the development, differentiation, and homeostasis of the gut.
Stephanie Holst, Jennifer L. Wilding, Kamila Koprowska, Yoann Rombouts, Manfred Wuhrer   +4 more
doaj   +1 more source

Metabolism of fucose, alpha-L-fucosidases, and fucosyltransferases: Enzymatic characterization, mechanism of catalysis and physiological role.

, 2019
Os carboidratos são moléculas diversas e complexas que são empregadas por organismos vivos em funções biológicas, como eventos energéticos, estruturais e de sinalização. L-Fucose é um monossacarídeo presente em diversos grupos biológicos, como mamíferos,
Perrella, Natalia Nappi
core   +1 more source

Gut Microbiota and Ischemic Stroke: From Pre‐Stroke Dysbiosis and Acute‐Phase Changes to Therapeutic Applications

Brain and Behavior, Volume 16, Issue 8, August 2026.
Abstract Purpose Ischemic stroke poses a major global health burden, and growing evidence points to the microbiota–gut–brain axis as an important contributor to stroke pathophysiology and recovery. The purpose of this review is to summarize current knowledge on bidirectional gut‐brain communication in stroke, establishing gut dysbiosis as an upstream ...
Ruihui Weng, Gaolei Dong, Jianxin Tang, Yu Zhao   +3 more
wiley   +1 more source

Helicobacter hepaticus Hh0072 gene encodes a novel α1-3-fucosyltransferase belonging to CAZy GT11 family

, 2010
Lewis x (Lex) and sialyl Lewis x (SLex)-containing glycans play important roles in numerous physiological and pathological processes. The key enzyme for the final step formation of these Lewis antigens is α1-3-fucosyltransferase. Here we report molecular
Huang, Shengshu, Lau, Kam, Wang, Peng G, Sugiarto, Go, Li, Yanhong, Zhang, Lei, Yu, Hai, Chen, Xi, Ding, Li, Cheng, Jiansong, Thon, Vireak   +10 more
core   +1 more source

The Role of Alpha 1,3 Fucosyltransferases in Haemopoieses and Haemopoietic Cell Migration

, 2015
α1,3 fucosylation is crucial in the formation of functional ligands for interaction with their corresponding selectin(s). These interactions regulate leukocyte migration and normal haemopoiesis.
Khoo, Teh-Liane
core  

Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation

Scientific Reports, 2017
Glycosylation of uterine endometrial cells plays important roles to determine their receptive function to blastocysts. Trophoblast-derived pregnancy-associated plasma protein A (PAPPA) is specifically elevated in pregnant women serum, and is known to ...
Ming Yu, Jiao Wang, Shuai Liu, Xiaoqi Wang, Qiu Yan   +4 more
doaj   +1 more source

Using Eukaryotic Expression Systems to Generate Human α1,3 Fucosyltransferases that Effectively Create Selectin-binding Glycans on Stem Cells

, 2020
Recruitment of circulating cells towards target sites is primarily dependent on selectin/ligand adhesive interactions.Glycosyltransferases are involved in the creation of selectin ligands on proteins and lipids.
Izpisua Belmonte, Juan Carlos, Lee, Jae Man, Ali, Amal J., Tehseen, Muhammad, Merzaban, Jasmeen, Sakashita, Kosuke, Zhou, Ruoyu, Al-Amoodi, Asma S., Li, Mo, Kusakabe, Takahiro   +9 more
core   +1 more source

Production of human fucosyltransferases in Trichoderma reesei

, 2017
Theoretical thesis.Bibliography: pages 163-210.1. Introduction -- 2. Materials and methods -- 3. Expression of the recombinant FUT3 and FUT4 in Trichoderma reesei -- 4. Optimisation of culture conditions -- 5.
Gryshyna, Anna
core  

Characterization of a Novel α1,2-Fucosyltransferase of Escherichia coli O128:B12 and Functional Investigation of Its Common Motif

, 2016
The wbsJ gene from Escherichia coli O128:B12 encodes an α1,2-fucosyltransferase responsible for adding a fucose onto the galactose residue of the O-antigen repeating unit via an α1,2 linkage. The wbsJ gene was overexpressed in E.
Jing K. Song (2459851), Xian-Wei Liu (1793137), Jun Shao (1649449), Peng George Wang (256049), Robert Woodward (1450681), Mei Li (217363), Christine S. Chow (2082214), Jie Shen (31533), Qiang Jia (302701), Wen Yi (1284069)   +9 more
core   +1 more source

Characterizing human α-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases [PDF]

, 2020
Mammalian Asn-linked glycans are extensively processed as they transit the secretory pathway to generate diverse glycans on cell surface and secreted glycoproteins.
Wang, Lai-Xi, Zong, Guanghui, Ramiah, Annapoorani, Moremen, Kelley W, Boruah, Bhargavi M, Bosman, Gerlof P, Wood, Zachary A, Kadirvelraj, Renuka, Yang, Jeong-Yeh, Li, Chao, Liu, Lin, Boons, Geert-Jan, Afd Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery, Sub Chemical Biology and Drug Discovery   +14 more
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