Results 101 to 110 of about 3,115 (208)

Glycosyltransferase Activity Can Be Modulated by Small Conformational Changes of Acceptor Substrates^†

, 2016
A range of N-acetyllactosamine derivatives (compounds 4−7) that have restricted mobilities around their glycosidic linkages have been employed to determine how small changes in conformational properties of an oligosaccharide acceptor affect catalytic ...
Geert-Jan Boons (212062), Andre P. Venot (2947866), M. Carmen Galan (1366494)   +2 more
core   +1 more source

Human alfa3-fucosyltransferases convert chitin oligosaccharides to products containing a GlcNacbeta1-4(Fucalfa1-3)GlcNAc beta1-4R determinant at the nonreducing terminus

, 2001
Human alpha3-fucosyltransferases (Fuc-Ts) are known to convert N-acetyllactosamine to Gal beta1-4(Fuc alpha1-3)GlcNAc (Lewis x antigen); some of them transfer fucose also to GalNAc beta1-4GlcNAc, generating GalNAc beta1-4(Fuc alpha1-3)GlcNAc determinants.
Natunen, Jari, Niemelä, Ritva, Helin, Jari, Maaheimo, Hannu, Heikkinen, Sami, Aitio, Olli, Renkonen, Ossi   +6 more
core   +1 more source

Integrating transcriptomics, glycomics and glycoproteomics to characterize hepatitis B virus-associated hepatocellular carcinoma

Cell Communication and Signaling
Background Hepatocellular carcinoma (HCC) ranks as the third most common cause of cancer related death globally, representing a substantial challenge to global healthcare systems.
Zhuo Li, Na Zhang, Zewen Dong, Xin Wang, Jian Zhou, Juan Gao, Yunyun Yang, Jing Li, Feng Guan, Yue Zhou, Zengqi Tan   +10 more
doaj   +1 more source

Review Definition of immunogenic carbohydrate epitopes [PDF]

, 2005
Carbohydrates are known as sources of immunological cross-reactivity of allergenic significance. In celery and in cypress pollen, the major allergens Api g 5 and Cup a 1 are recognised by an-tisera raised against anti-horseradish peroxidase and by ...
Iain B. H. Wilson, David Schuster, Dubravko Rendić, Gustáv Fabini, Schuster, David, Fabini, Gustáv, Katharina Paschinger, Paschinger, Katharina, Wilson, Iain, Rendić, Dubravko   +9 more
core  

A nuclear fucosyltransferase-like protein, PtFUT, from marine red alga Pyropia tenera (Rhodophyta) confers osmotic stress tolerance

, 2018
Pyropia tenera is a marine red alga that grows in the intertidal zone and may lose more than 90% of its water during twice-daily low tides. Based on the differentially expressed genes (DEGs) identified from the desiccation transcriptome of P.
S Yang, M S Hwang, S Im, J Wi, Won Joong Jeong, D W Choi, E J Park, H S Jung   +7 more
core   +1 more source

Production of recombinant proteins using prokaryotic and eukaryotic expression systems

, 2020
A recombinant enzyme PNGase H+ was produced in E. coli, and several steps were tried to optimize the expression, extraction and purification. Furthermore, PCR primers were designed to detect genes of predicted sialyltransferases, fucosyltransferases and ...
STEMMER, Vitus
core  

Creating a novel tobacco chassis with downregulated expression of α-1，3-fucosyltransferase 4

上海师范大学学报. 自然科学版
Tobacco (Nicotiana tabacum) is a widely used platform for producing recombinant proteins for clinical applications. However, achieving mammalian-like glycosylation modifications in plant-derived therapeutic proteins remains challenging, particularly in ...
SHAN Xuemeng, MUHAMMAD Naeem, WANG Yangzhong, HAN Rong, ZHOU Mengqian, ZHAO Weihua, ZHAO Lingxia   +6 more
doaj   +1 more source

Corrigendum: Fucosylated Antigens in Cancer: An Alliance Toward Tumor Progression, Metastasis, and Resistance to Chemotherapy

Frontiers in Oncology, 2018
Athanasios Blanas, Neha M. Sahasrabudhe, Ernesto Rodríguez, Yvette van Kooyk, Sandra J. van Vliet   +4 more
doaj   +1 more source

The role of fucosyltransferases and E-selectin binding in breast cancer metastasis

, 2015
Breast cancer metastasis is one of the leading causes of death among women. E-selectin, which has come under the focus of cancer metastasis studies, has been shown to play an important role in breast cancer metastasis in vitro, but evidence for E ...
Cheung, Corey
core  

1.Potentials of Chinese herbal medicine in ameliorating septic shock 2.Fucosyltransferases in breast cancer

, 2007
Section I. Potentials of Chinese herbal medicine in ameliorating septic shock Previous studies have shown that the fucose-containing glycoprotein fraction 3 (Reishi-F3) purified from the ancient Chinese herb – Ganoderma lucidum (Reishi) extract contains
李佩珊, Lee, Peishan
core