Results 211 to 220 of about 24,047 (253)

Fumonisin mycotoxins in human hair

Biomarkers, 2003
This study shows for the first time the accumulation of fumonisin mycotoxins in human hair of population clusters exposed to contaminated maize, and thus the feasibility of human hair analysis for the assessment of past fumonisin exposure. Composite hair samples were obtained from the Bizana, Butterworth and Centane districts within the Transkei region
Vikash, Sewram, Ndumiso, Mshicileli, Gordon S, Shephard, Walter F O, Marasas   +3 more
openaire   +2 more sources

Chemical Transformation of Hydrolyzed Fumonisin B1 to Hydrolyzed Fumonisin B2

Journal of Agricultural and Food Chemistry, 1995
The fumonisins, a series of sphingosine-analog mycotoxins produced by the ubiquitous corn contaminant Fusarium moniliforme, are an important food safety concern because they are tumor promoters with sufficient chemical stability to persist through normal food processing.
Farid A. Badria, Hamed K. Abbas, W. Thomas Shier   +2 more
openaire   +1 more source

Determination of fumonisins in milk

Journal of Environmental Science and Health, Part B, 1994
Fumonisin B1 (FB1) and fumonisin B2 (FB2) were determined in milk by liquid chromatography (LC) following immunoaffinity column cleanup. Recoveries from milk spiked with 5-50 ng each fumonisin/ml averaged 79-109%. The aminopentol hydrolysis product of FB1 (AP1) was determined by LC after cleanup on a C18 solid phase phase extraction column; mean ...
P M, Scott, T, Delgado, D B, Prelusky, H L, Trenholm, J D, Miller   +4 more
openaire   +2 more sources

Fumonisins and human health

Annals of Tropical Paediatrics, 1998
Fumonisins are mycotoxins produced by Fusarium moniliforme that are prevalent in corn, sorghum, millet and other agricultural products. It is possible that fumonisins are aetiological agents in human oesophageal cancers. The International Agency for Research on Cancer have designated toxins derived from F. moniliforme as group 2B (possibly carcinogenic
openaire   +2 more sources

Hidden fumonisin in corn flakes

Food Additives & Contaminants, 2003
Twenty-five samples of retail corn flakes (from 15 lots) were analysed for fumonisin B(1) (FB(1)) and fumonisin B(2) (FB(2)). They were detected in 22 and 12 samples, respectively, at respective mean concentrations 68 and 8 ng g(-1). Samples were extracted with methanol-acetonitrile-water (25:25:50) and there was an excellent correlation for FB(1 ...
Eun-Kyung, Kim, P M, Scott, B P-Y, Lau
openaire   +2 more sources

Foods and fumonisins

European Food Research and Technology, 2001
Fumonisins are synthesized by different species of the genus Fusarium but the most significant producers are Fusarium moniliforme and Fusarium proliferatum. The fumonisins belong to the most important toxic fungal metabolites. Maize and maize products are mainly contaminated.
openaire   +1 more source

Fumonisin Toxicity and Sphingolipid Biosynthesis

1996
Fumonisins are inhibitors of sphinganine (sphingosine) N-acyltransferase (ceramide synthase) in vitro, and exhibit competitive-type inhibition with respect to both substrates of this enzyme (sphinganine and fatty acyl-CoA). Removal of the tricarballylic acids from fumonisin B1 reduces the potency by at least 10 fold; and fumonisin A1 (which is ...
A H, Merrill, E, Wang, T R, Vales, E R, Smith, J J, Schroeder, D S, Menaldino, C, Alexander, H M, Crane, J, Xia, D C, Liotta, F I, Meredith, R T, Riley   +11 more
openaire   +2 more sources

Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
Sphingoid bases are growth inhibitory and pro-apoptotic for many types of cells when added to cells exogenously, and can be elevated to toxic amounts endogenously when cells are exposed to inhibitors of ceramide synthase. An important category of naturally occurring inhibitors are the fumonisins, which inhibit ceramide synthase through structural ...
Kena, Desai, M Cameron, Sullards, Jeremy, Allegood, Elaine, Wang, Eva M, Schmelz, Michaela, Hartl, Hans-Ulrich, Humpf, D C, Liotta, Qiong, Peng, Alfred H, Merrill   +9 more
openaire   +2 more sources

Induction of apoptosis in cultured human proximal tubule cells by fumonisins and fumonisin metabolites

Mycotoxin Research, 2001
It is well-known that fumonisin B1 (FB1) stimulates apoptosis in a variety of cell types and tissues but the apoptotic potential of other fumonisins and fumonisin metabolites has not been investigated. In our studies we exposed human proximal tubule-derived cells (IHKE cells) to FB1, fumonisin B2 (FB2), hydrolyzed fumonisin B1 (HFB1) and N-palmitoyl ...
W, Seefelder, H-U, Humpf, G, Schwerdt, R, Freudinger, M, Gekle   +4 more
openaire   +3 more sources

Immunochemical Methods for Fumonisins

1996
Both monoclonal and polyclonal antibodies have been raised against fumonisins (Fm) and the hydrolyzed toxin in several laboratories. They have been used in several immunoassays and can detect 5 to 5000 ng of FmB1/mL in a "clean" standard solution. However, sample matrices still give severe interferences.
openaire   +2 more sources