Results 181 to 190 of about 10,046 (225)

Effects of Fumonisin B1 in Pregnant Rats

Food and Chemical Toxicology, 1998
Fumonisin B1 (FB1), the major mycotoxin from Fusarium moniliforme, has been implicated as a causative agent in several animal and human diseases. Despite animal toxicity studies and human epidemiological studies of FB1, knowledge of its reproductive effects is scarce.
T F, Collins, M E, Shackelford, R L, Sprando, T N, Black, J B, Láborde, D K, Hansen, R M, Eppley, M W, Trucksess, P C, Howard, M A, Bryant, D I, Ruggles, N, Olejnik, J I, Rorie   +12 more
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Developmental effects of fumonisin B1 in mice

Mycopathologia, 1996
Developmental and toxic effects of aqueous extracts of F. moniliforme culture material containing known levels of fumonisin B1 were recently reported in mice and included maternal hepatotoxicity and lethality, maternal body weight gain reduction, increased embryonic resorptions, reduced offspring body weights, and fetal malformations including cleft ...
R V, Reddy, G, Johnson, G E, Rottinghaus, S W, Casteel, C S, Reddy   +4 more
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Detection of fumonisins B1, B2, and B3 and hydrolyzed fumonisin B1 in corn-containing foods

Journal of Agricultural and Food Chemistry, 1993
Selected corn-containing foods were analyzed for the presence of fumonisins B 1 , B 2 and B 3 (FB 1 , FB 2 , and FB 3 ) and hydrolyzed fumonisin B 1 (HFB 1 ). Samples were extracted with H 2 O/CH 3 CN (1:1). Following a cleanup procedure using a C 18 SPE cartridge, analytical reversed-phase HPLC and fluorometric detection of the o-phthaldialdehyde ...
Ellen C. Hopmans, Patricia A. Murphy
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DNA Damage in Astrocytes Exposed to Fumonisin B1

Neurochemical Research, 2002
Fumonisins are a group of toxic metabolites mainly produced by Fusarium moniliforme and Fusarium proliferatum, fungi that commonly occur on corn throughout the world. Fumonisin B1 (FB1), structurally resembling sphingoid bases, is an inhibitor of ceramide synthase, a key enzyme involved in de novo sphingolipid biosynthesis and in the reacylation of ...
GALVANO, Fabio, CAMPISI, Agatina, RUSSO, Alessandra, G. GALVANO, M. PALUMBO, RENIS, Marcella, M. L. BARCELLONA, J. R. PEREZ POLO, A. VANELLA   +8 more
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In Vitro Metabolism of Fumonisin B1 by Ruminal Microflora

Veterinary Research Communications, 2000
Fumonisin B1 (FB1) is a mycotoxin produced by Fusarium moniliforme and F. proliferatum. Little is known of its metabolic fate after oral ingestion in ruminants, but these animals are reported to be tolerant towards FB1. The metabolism of this mycotoxin was evaluated following incubation (1 microg/ml) in ruminal fluid for up to 72 h, in the presence or ...
Caloni, F., Spotti, M., Auerbach, H., Op den Camp, H., Fink-Gremmels, J., Pompa, G.   +5 more
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Synthesis of analogs of fumonisin B1

Journal of Agricultural and Food Chemistry, 1992
The fungus Fusarium moniliforme Sheldon is one of the most important ear rot pathogens of corn (Nyvall, 1983). The toxicity of the mold was initially discovered when an isolate of F. moniliforme from corn grown in an area of Africa with a high incidence of esophageal cancer was tested (Marasas et al., 1981).
Kraus, George, Applegate, Jacqueline, Reynolds, Don   +2 more
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Initial studies on the toxicokinetics of fumonisin B1 in rats

Food and Chemical Toxicology, 1992
Fumonisin B1 (FB1), the major compound in the fumonisin group of secondary metabolites of Fusarium moniliforme Sheldon, is associated with some human and animal diseases. After intraperitoneal dosing to rats (7.5 mg/kg), FB1 was rapidly absorbed and reached a maximum concentration in plasma within 20 min after injection.
G S, Shephard, P G, Thiel, E W, Sydenham
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Occurrence of fumonisin B1 in maize imported into Taiwan

International Journal of Food Microbiology, 2001
Samples of maize imported into Taiwan during 1997-1998 were collected and analyzed for the presence of fumonisin B1 (FB1) using high performance liquid chromatography. Eight (6.8%) of 118 samples were found to contain FB1 (334-1614 microg kg(-1)). The frequency of FB1 found in maize samples imported from Australia was 20%, followed by Thailand (10 ...
T C, Tseng, C Y, Liu
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Biliary excretion of the mycotoxin fumonisin B1 in rats

Food and Chemical Toxicology, 1994
The biliary excretion of the mycotoxin fumonisin B1 (FB1), produced by the fungus Fusarium moniliforme Sheldon, has been measured in male Wistar rats. After ip injection of a solution of FB1 (7.5 mg/kg body weight), 67% of the applied dose was recovered in bile over a 24-hr period, 88% of this recovery being excreted in the first 4 hr after dosing.
G S, Shephard, P G, Thiel, E W, Sydenham, J F, Alberts   +3 more
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Antinutritional effects of fumonisin B1 and pathophysiological consequences

Toxicology Letters, 2003
Due to its structural similarity with sphingosine, fumonisin B(1) (FB(1)) inhibits ceramide synthase (a key enzyme of sphingolipid biosynthesis) leading to an intracellular accumulation of sphingoid bases with a consequent increase of sphinganine/sphingosine (SA/SO) ratio. In adult male rats, dietary exposure to fumonisin induces a significant increase
CARRATU' M. R, CASSANO T, COLUCCIA A, BORRACCI P, CUOMO, VINCENZO   +4 more
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