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Mechanisms of Fumonisin B1 Toxicity: A Computational Perspective beyond the Ceramide Synthases Inhibition.

Chemical Research in Toxicology, 2018
Fumonisins are mycotoxins produced by Fusarium fujikuroi species complex that may contaminate food and feed threatening human and animal health. Among the fumonisins group, fumonisin B1 is the most widespread and best characterized in terms of toxicity ...
L. Dellafiora   +2 more
semanticscholar   +1 more source

Chemical Transformation of Hydrolyzed Fumonisin B1 to Hydrolyzed Fumonisin B2

Journal of Agricultural and Food Chemistry, 1995
The fumonisins, a series of sphingosine-analog mycotoxins produced by the ubiquitous corn contaminant Fusarium moniliforme, are an important food safety concern because they are tumor promoters with sufficient chemical stability to persist through normal food processing.
Farid A. Badria   +2 more
openaire   +1 more source

Fumonisin B1 alters sphingolipid metabolism and immune function in BALB/c mice: Immunological responses to fumonisin B1

Mycopathologia, 1995
Fumonisins have been reported to have diverse effects on animals, including immunosuppression in chickens and feeder calves; therefore, the effects of fumonisin B1 (FB1) on immune function in BALB/c mice was investigated. When administered i.p. with sheep red blood cells (SRBC), 5 to 100 micrograms of FB1 reduced the number of plaque-forming cells (PFC)
E A, Martinova, A H, Merrill
openaire   +2 more sources

Effects of prolonged oral administration of fumonisin B1 and aflatoxin B1 in rats

Mycopathologia, 2001
The effects of prolonged oral administration (21 days) of fumonisin B1 (FB1) and aflatoxin B1 (AFB1) were evaluated on male Wistar rats. The animals were housed in individual metabolic cages and submitted to the following treatments: 1-0 microg AFB1 + 0 mg FB1/100g bw.; 2-72 microg AFB1+ 0 mg FB1/100 g bw; 3-0 microg AFB1 + 0.5 mg FB1 g bw; 4-0 microg ...
Pozzi, C. R.   +5 more
openaire   +3 more sources

Fumonisin B1 triggers carcinogenesis via HDAC/PI3K/Akt signalling pathway in human esophageal epithelial cells.

Science of the Total Environment, 2021
S. Yu   +5 more
semanticscholar   +1 more source

Analysis of Fumonisin B1 in Corn by Capillary Electrophoresis

1996
Intact fumonisins contain two tricarballylic acid groups and can therefore acquire a net negative charge. The anionic nature of the fumonisins is the basis behind the widely used method for cleanup of corn with strong anion exchange (SAX) columns. This property also enables the fumonisins to be separated by electrophoretic techniques which, until now ...
C M, Maragos, G A, Bennett, J L, Richard
openaire   +2 more sources

Colorimetric immunoassay via smartphone based on Mn2+-Mediated aggregation of AuNPs for convenient detection of fumonisin B1

, 2022
Yao Yu   +7 more
semanticscholar   +1 more source

Fumonisin B1 is fetotoxic in rats.

Veterinary and human toxicology, 1995
Groups of 5-6 pregnant F344/N rats were dosed (po) from d 8 to 12 of gestation with 30 or 60 mg purified fumonisin B1 (FB1)/kg body weight, or with a fat-soluble extract of Fusarium proliferatum/corn culture derived from an amount of corn culture that would provide approximately 60 mg FB1/kg. Control rats were dosed with water or corn oil.
S, Lebepe-Mazur   +4 more
openaire   +1 more source

Early toxic effects of fumonisin B1 in rat liver

Human & Experimental Toxicology, 2008
Mycotoxin fumonisin B 1 (FB 1 ) is hepatotoxic and carcinogenic in experimental animals. It is known that long-term exposure of experimental animals to FB 1 causes apoptosis and lipid peroxidation.
Domijan, Ana-Marija   +7 more
openaire   +3 more sources

Fumonisin B1 induced aggressiveness and infection mechanism of Fusarium proliferatum on banana fruit.

Environmental Pollution, 2021
Lihong Xie   +6 more
semanticscholar   +1 more source

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