Results 91 to 100 of about 302,091 (291)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Padé approximant related to asymptotics for the gamma function

open access: yesJournal of Inequalities and Applications, 2017
Based on the Padé approximation method, we determine the coefficients a j $a_{j}$ and b j $b_{j}$ ( 1 ≤ j ≤ k $1\leq j\leq k$ ) such that Γ ( x + 1 ) 2 π x ( x / e ) x = x k + a 1 x k − 1 + ⋯ + a k x k + b 1 x k − 1 + ⋯ + b k + O ( 1 x 2 k + 1 ) , x → ∞ ,
Xin Li, Chao-Ping Chen
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

АППРОКСИМАЦИЯ СИЛЫ СОПРОТИВЛЕНИЯ ВОЗДУХА ДВИЖЕНИЮ СНАРЯДОВ АНАЛИТИЧЕСКИМИ ФУНКЦИЯМИ

open access: yesSučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2015
В статтье проводится выбор и обоснование аналитических функций, которые используются для описания силы сопротивления воздуха. Рассматриваются характерные участки и особенности изменения функций сопротивления воздуха в зависимосты от скорости полета ...
Volodymir I. Grabchac   +2 more
doaj  

Metrical Approximations of Functions

open access: yesFunkcialaj Ekvacioj
In this paper, we analyze metrical approximations of functions $F :Λtimes X \rightarrow Y$ by trigonometric polynomials and $ρ$-periodic type functions, where $\emptyset \neq Λ\subseteq {\mathbb R}^{n},$ $X$ and $Y $are complex Banach spaces, and $ρ$ is a general binary relation on $Y .$ Besides the classical concept, we analyze Stepanov,Weyl ...
Chaouchi, Belkacem   +2 more
openaire   +2 more sources

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