Results 81 to 90 of about 832,157 (268)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Bisimilarity as a Theory of Functional Programming

open access: yesElectronic Notes in Theoretical Computer Science, 1995
The objektive of this paper is to use CCS-style labbelled transitions and bisimilarity to offer a new perspective on the behavior of functional programs. Morris-style contextual equivalence is characterized in terms of reduction behavior and production of values.
openaire   +1 more source

Lexicography for the third millennium: Cognitive-oriented specialised dictionaries for learners [PDF]

open access: yesIbérica, 2011
Emphasis on the functional approach to lexicography, for example the so-called Function Theory of Lexicography proposed by Bergenholtz and Tarp (2002, 2003 & 2004; see Tarp 2008 for a review), has promoted the vision that lexicography is at a crossroads ...
Pedro A. Fuertes-Olivera, Sven Tarp
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Lexicography for the third millennium

open access: yesIbérica, 2011
Emphasis on the functional approach to lexicography, for example the so-called Function Theory of Lexicography proposed by Bergenholtz and Tarp (2002, 2003 & 2004; see Tarp 2008 for a review), has promoted the vision that lexicography is at a crossroads ...
Pedro Antonio Fuertes Olivera, Sven Tarp
doaj  

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