Results 271 to 280 of about 361,695 (297)
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2019
The deluge of sequencing data needs curated association of structural and functional features to each sequence in the database. Inference of correct annotation is a major problem of sequence analysis. We highlight why it is difficult to solve the annotation task given the little amount of validated information in the database linking sequences ...
Pier Luigi Martelli +2 more
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The deluge of sequencing data needs curated association of structural and functional features to each sequence in the database. Inference of correct annotation is a major problem of sequence analysis. We highlight why it is difficult to solve the annotation task given the little amount of validated information in the database linking sequences ...
Pier Luigi Martelli +2 more
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Resources for functional annotation
2008The continued success of genome sequencing projects has led to an explosion in the availability of sequence data. The Genomes On Line Database (GOLD) currently lists more than 2000 ongoing and completed genome projects, and this number is continuously increasing (Liolios et al. 2008).
A. J. Bridge +2 more
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Comparison of functional annotation schemes for genomes
Functional & Integrative Genomics, 2000In this paper we survey a number of functional classification schemes applicable to genomes. We present the concepts of depth, breadth and resolution as descriptors of the schemes' scope and architecture and compare selected classifications according to these criteria.
S C, Rison, T C, Hodgman, J M, Thornton
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Manual Gene Curation and Functional Annotation
2018No genome sequencing project is complete without structural and functional annotation. Gene models and functional predictions for these models can be obtained relatively easily using computational methods, but they are prone to errors. We describe herein the steps we use to manually curate gene models and functionally annotate them.
Erin, McDonnell +2 more
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Microarray Annotation and Biological Information on Function
Methods of Information in Medicine, 2005Summary Objectives: Many methods for statistical analysis of gene expression studies by DNA microarrays produce lists of genes as output. To understand gene lists in terms of traditional biology, e.g. which pathways may be affected, it is necessary to get appropriate annotations for the probes on an array.
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Variant Annotation and Functional Prediction: SnpEff
2012Variant annotations, in general, refer to the process of information enrichment of genomic variants from a sequencing experiment. Typically these annotations include functional predictions, such as predicting the amino acid sequence changes from the DNA variant, predicting whether the variant will induce a splice anomaly, or predicting nonsense ...
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Computational prediction of protein functional annotations
Protein function prediction is a crucial task in bioinformatics and computational biology, as it enables the understanding of disease mechanisms, development of new therapeutics, and improvement of crop yields. Despite significant advances, the majority of protein functions remain unknown or poorly annotated, hindering our understanding of biological ...Maxat, Kulmanov, Robert, Hoehndorf
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EnTAP : Bringing faster and smarter functional annotation to non‐model eukaryotic transcriptomes
Molecular Ecology Resources, 2020Cera R Fisher +2 more
exaly
TOA: A software package for automated functional annotation in non‐model plant species
Molecular Ecology Resources, 2021Fernando Mora-Márquez +2 more
exaly