Results 31 to 40 of about 557,186 (345)
Re-annotation is an essential step in systems biology modeling of functional genomics data. [PDF]
PLoS ONE, 2010 One motivation of systems biology research is to understand gene functions and interactions from functional genomics data such as that derived from microarrays.
Bart H J van den Berg +3 more
doaj +1 more source
MoKCa database - mutations of kinases in cancer [PDF]
, 2009 Members of the protein kinase family are amongst the most commonly mutated genes in human cancer, and both mutated and activated protein kinases have proved to be tractable targets for the development of new anticancer therapies The MoKCa database ...
Alfarano +47 more
core +3 more sources
Tissue resolved, gene structure refined equine transcriptome. [PDF]
, 2017 BackgroundTranscriptome interpretation relies on a good-quality reference transcriptome for accurate quantification of gene expression as well as functional analysis of genetic variants.
Bellone, RR +9 more
core +1 more source
Frontiers in Genetics, 2014 With the advancement of new high throughput sequencing technologies, there has been an increase in the number of genome sequencing projects worldwide, which has yielded complete genome sequences of human, animals and plants.
Gaston K Mazandu, Nicola eMulder
doaj +1 more source
Evidence attribution in the UniProt Knowledgebase [PDF]
, 2009 UniProtKB provides the scientific community with a comprehensive collection of protein sequence records containing extensive curated information including functional and sequence annotation.
Michele Magrane, UniProt Consortium
core +2 more sources
SFannotation: A Simple and Fast Protein Function Annotation System [PDF]
Genomics & Informatics, 2014 Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation ...
Dong Su Yu, Byung Kwon Kim
doaj +1 more source
The Bologna Annotation Resource (BAR 3.0): improving protein functional annotation [PDF]
Nucleic Acids Research, 2017 BAR 3.0 updates our server BAR (Bologna Annotation Resource) for predicting protein structural and functional features from sequence. We increase data volume, query capabilities and information conveyed to the user. The core of BAR 3.0 is a graph-based clustering procedure of UniProtKB sequences, following strict pairwise similarity criteria (sequence ...
PROFITI, GIUSEPPE +2 more
openaire +3 more sources
The first draft genome assembly and data analysis of the Malaysian mahseer (Tor tambroides)
Aquaculture and Fisheries, 2023 The Malaysian mahseer (Tor tambroides), one of the most valuable freshwater fish in the world, is mainly targeted for human consumption. The mitogenomic data of this species is available to date, but the genomic information is still lacking.
Melinda Mei Lin Lau +3 more
doaj +1 more source
Clinically Relevant Functional Annotation of Genotype [PDF]
Circulation: Cardiovascular Genetics, 2014 Genetic testing was originally thought likely to generate deterministic predictions of many clinical outcomes in inherited disorders. Indeed, this premise was one of the original drivers of the precision medicine movement. However, the variable expression of final phenotypes even in the setting of large genetic effects has long reinforced the ...
Calum A, MacRae, Ramachandran S, Vasan
openaire +2 more sources
Functional annotation strategy for protein structures [PDF]
Bioinformation, 2007 Whole-genome sequencing projects are a major source of unknown function proteins. However, as predicting protein function from sequence remains a difficult task, research groups recently started to use 3D protein structures and structural models to bypass it.
Olivia, Doppelt +3 more
openaire +2 more sources