Results 51 to 60 of about 557,186 (345)

Functional annotation and ENU

BMC Research Notes, 2012
Abstract Functional annotation of every gene in the mouse genome is a herculean task that requires a multifaceted approach. Many large-scale initiatives are contributing to this undertaking. The International Knockout Mouse Consortium (IKMC) plans to mutate every protein-coding gene, using a combination of gene trapping and gene targeting in ...
openaire   +2 more sources

miRAnno—network-based functional microRNA annotation

Bioinformatics, 2021
Abstract Motivation Functional annotation is a common part of microRNA (miRNA)-related research, typically carried as pathway enrichment analysis of the selected miRNA targets. Here, we propose miRAnno, a fast and easy-to-use web application for miRNA annotation.
Tomas Tokar, Chiara Pastrello, Mark Abovsky, Sara Rahmati, Igor Jurisica   +4 more
openaire   +2 more sources

Assessing the performance of different approaches for functional and taxonomic annotation of metagenomes

BMC Genomics, 2019
Background Metagenomes can be analysed using different approaches and tools. One of the most important distinctions is the way to perform taxonomic and functional assignment, choosing between the use of assembly algorithms or the direct analysis of raw ...
Javier Tamames, Marta Cobo-Simón, Fernando Puente-Sánchez   +2 more
doaj   +1 more source

Protein family classification and functional annotation [PDF]

Computational Biology and Chemistry, 2003
With the accelerated accumulation of genomic sequence data, there is a pressing need to develop computational methods and advanced bioinformatics infrastructure for reliable and large-scale protein annotation and biological knowledge discovery. The Protein Information Resource (PIR) provides an integrated public resource of protein informatics to ...
Cathy H, Wu, Hongzhan, Huang, Lai-Su L, Yeh, Winona C, Barker   +3 more
openaire   +2 more sources

Representation of non-coding RNA-mediated regulation of gene expression using the Gene Ontology

RNA Biology
Regulatory non-coding RNAs (ncRNAs) are increasingly recognized as integral to the control of biological processes. This is often through the targeted regulation of mRNA expression, but this is by no means the only mechanism through which regulatory ...
Giulia Antonazzo, Pascale Gaudet, Ruth C. Lovering, Helen Attrill   +3 more
doaj   +1 more source

Assessment of genome annotation using gene function similarity within the gene neighborhood

BMC Bioinformatics, 2017
Background Functional annotation of bacterial genomes is an obligatory and crucially important step of information processing from the genome sequences into cellular mechanisms. However, there is a lack of computational methods to evaluate the quality of
Se-Ran Jun, Intawat Nookaew, Loren Hauser, Andrey Gorin   +3 more
doaj   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

GNPAnnot community annotation system applied to sugarcane bac clone sequences (W572) [PDF]

, 2011
A large amount of data is being produced by current genome sequencing projects. Sequence annotations and analyses need to be organized into databases and widely accessible.
Bocs, Stéphanie, Charron, Carine, D'Hont, Angélique, Droc, Gaëtan, Garsmeur, Olivier, Guignon, Valentin   +5 more
core  

Functional Annotation Analytics of Genomes

Bioinformatics and Biology Insights, 2011
Rhodopseudomonas palustris , a nonsulphur purple photosynthetic bacteria, has been extensively investigated for its metabolic versatility including ability to produce hydrogen gas from sunlight and biomass.
Shaneka S. Simmons, Raphael D. Isokpehi, Shyretha D. Brown, Donee L. Mcallister, Charnia C. Hall, Wanaki M. Mcduffy, Tamara L. Medley, Udensi K. Udensi, Rajendram V. Rajnarayanan, Wellington K. Ayensu, Hari H.P. Cohly   +10 more
doaj   +1 more source

ProFAB—open protein functional annotation benchmark

Briefings in Bioinformatics, 2023
AbstractAs the number of protein sequences increases in biological databases, computational methods are required to provide accurate functional annotation with high coverage. Although several machine learning methods have been proposed for this purpose, there are still two main issues: (i) construction of reliable positive and negative training and ...
A Samet Özdilek, Ahmet Atakan, Gökhan Özsarı, Aybar Acar, M Volkan Atalay, Tunca Doğan, Ahmet S Rifaioğlu   +6 more
openaire   +3 more sources