Results 81 to 90 of about 759,413 (161)

Endothelial calcium firing mediates the extravasation of metastatic tumor cells

iScience
Summary: Metastatic dissemination is driven by genetic, biochemical, and biophysical cues that favor the distant colonization of organs and the formation of life-threatening secondary tumors.
Marina Peralta, Amandine Dupas, Annabel Larnicol, Olivier Lefebvre, Ruchi Goswami, Tristan Stemmelen, Anne Molitor, Raphael Carapito, Salvatore Girardo, Naël Osmani, Jacky G. Goetz   +10 more
doaj   +1 more source

Is the Cell Really a Machine? [PDF]

, 2019
It has become customary to conceptualize the living cell as an intricate piece of machinery, different to a man-made machine only in terms of its superior complexity.
Nicholson, Daniel J.
core  

Mitochondrial F0F1-ATP synthase governs the induction of mitochondrial fission

iScience
Summary: Mitochondrial dynamics is a process that balances fusion and fission events, the latter providing a mechanism for segregating dysfunctional mitochondria. Fission is controlled by the mitochondrial membrane potential (ΔΨm), optic atrophy 1 (OPA1)
Charlène Lhuissier, Valérie Desquiret-Dumas, Anaïs Girona, Jennifer Alban, Justine Faure, Julien Cassereau, Philippe Codron, Guy Lenaers, Olivier R. Baris, Naïg Gueguen, Arnaud Chevrollier   +10 more
doaj   +1 more source

β-adrenergic signaling modulates breast cancer cell mechanical behaviors through a RhoA-ROCK-myosin II axis

iScience
Summary: The ability of cancer cells to deform and generate force is implicated in metastasis. We previously showed that β-adrenergic agonists increase cancer cell stiffness, which was associated with enhanced motility and invasion.
Tae-Hyung Kim, Minh-Tam Tran Le, Mijung Oh, Esteban Vazquez-Hidalgo, Bryanna Chavez, Donald M. Lamkin, Alexander Abdou, Xing Haw Marvin Tan, Alexei Christodoulides, Carly M. Farris, Changhoon Lee, Pei-Yu Chiou, Erica K. Sloan, Parag Katira, Amy C. Rowat   +14 more
doaj   +1 more source

USP7 upregulated by TGF-β1 promotes ferroptosis via inhibiting LATS1-YAP axis in sepsis-induced acute lung injury

iScience
Summary: Our work aimed to investigate the interactive roles of transforming growth factor β1 (TGF-β1), ubiquitin-specific-processing protease 7 (USP7), and Yes-associated protein (YAP) in ferroptosis during sepsis-secondary acute lung injury (ALI).
Hong Lv, Jing Yu, Xingjia Qian, Jun Shu, Qiuhong Qian, Luhong Shen, Dongfang Shi, Zhengzheng Tao, Guiqin Fan, Bufeng Zhuang, Bing Lu   +10 more
doaj   +1 more source

Clathrin-mediated endocytosis as an axis for the etiopathogenesis of Parkinson's disease. [PDF]

J Cell Sci
Kaci A, Herbst S, Manzoni C, Lewis PA.
europepmc   +1 more source

Editorial: Advances in bacteriophage research & development with therapeutic applications. [PDF]

Front Cell Infect Microbiol
Gonzalez Moreno M, Alt S, Mercer D.
europepmc   +1 more source

Have plant cells been forgotten? [PDF]

, 2018
Russinova, Eugenia
core   +1 more source

Biogenesis and Regulation of Telomerase during Development and Cancer. [PDF]

Cold Spring Harb Perspect Biol
Chen L, Batista LFZ.
europepmc   +1 more source

Gene regulatory networks: from correlative models to causal explanations. [PDF]

Nat Rev Genet
Maizels RJ, Briscoe J.
europepmc   +1 more source