Results 271 to 280 of about 412,466 (343)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Xalnesiran with or without an immunomodulator in chronic hepatitis B: still a challenge in functional cure. [PDF]

Hepatobiliary Surg Nutr
Tang Q, Xue Y, Hu P.
europepmc   +1 more source

Adhesive Property of UV-curing Ink for Non-Porous Surface (I)<br/>^|^mdash;Influence of Di- and Tri-Functional Monomers^|^mdash;

, 2013
Kyoung-Mo Jeong, Ken rsquo ichi KOSEKI
openalex   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Functional cure with single agent olutasidenib in relapsed IDH1/NPM1 co-mutated AML. [PDF]

NPJ Precis Oncol
Watts J, Nong T, Micin K, Soong D, Madarang E, Affer M, Mehra S, Lesmes JA, Chapman J, Zhou Y, Thomassen A, Bradley T, Totiger T, Swords R, Taylor J.   +14 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Functional cure with new antiviral therapy for hepatitis B virus: a systematic review and meta-analysis. [PDF]

Hepatol Int
Chen J, Ji D, Jia J, Zhuang H, Zhang X, Wang FS, Zhang W, Dou X, Tanwandee T, Sarin SK, Maiwall R, Kumar M, Goh GB, Ghazinyan H, Chutaputti A, Chen PJ, You H, Yu ML, George J, Omata M, Wang GQ, Lau G, APASL Viral Elimination Taskforce.   +22 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Functional cure of chronic hepatitis B-hope or hype? [PDF]

World J Hepatol
Ray G.
europepmc   +1 more source