Results 261 to 270 of about 412,466 (343)

Improvements in functional properties of dry cured meat using fermented soy paste.

, 2014
Abdulatef M. Ahhmed, C. Bi̇ri̇şi̇k, Şadıman KARAMAN, İsmail Öztürk, Mehmet Bilgen, Gen Kaneko, Hideki Ushio, Ryoichi Sakata, Hasan Yetim   +8 more
openalex   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Transcriptional and functional HBV-specific CD8 T cell changes from disease to functional cure in HBeAg-negative chronic hepatitis B. [PDF]

JHEP Rep
Rossi M, Vecchi A, Tiezzi C, Guerrieri F, Plissonnier ML, Degasperi E, Sambarino D, Laccabue D, Alfieri A, Gabor EA, Penna A, Reverberi V, Montali A, Pelagatti A, Doselli S, Farina B, Pedrazzi G, Fisicaro P, Missale G, Lampertico P, Ferrari C, Levrero M, Boni C.   +22 more
europepmc   +1 more source

Hydroxyl-functional acrylic adhesives: leveraging polysilazane chemistry for curing

Amrita Chatterjee, Shashank Jha, Sushmit Sen, Keshav Dev, Chayan Das, Pradip K. Maji   +5 more
openalex   +2 more sources

On Sub-Acute Inflammation of the Ovaries and of the Fallopian Tubes, as One of the Causes of Functional Sterility: With Cases Illustrating the Practicability of its Cure [PDF]

EdwardJohn Tilt
openalex   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Safety and efficacy of PD-1 antibody combined with pegylated interferon α for functional cure in nucleos(t)ide analogues-suppressed chronic hepatitis B patients: protocol for a multicentre randomised controlled trial [PDF]

Hongmin Wang, Xiaoying Li, Junfeng Lu, Xin Zhang, Shuangsuo Dang, Yaping Li, Yingli He, Ying Guo, Jiaojiao Wang, Wubuliaishan Maimaitijiang, Sujun Zheng, Shan Ren, Haifang Cao, Wen‐Hua Zhang, Xiaoning Zhang, Hecheng Ma, Fusheng Wang, Junliang Fu   +17 more
openalex   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Drug development for chronic hepatitis B functional cure: Recent progress. [PDF]

World J Hepatol
Liu T, Wang H, Zhao Y, Wang YX, Xing X, Gao P.   +5 more
europepmc   +1 more source