Results 241 to 250 of about 155,433 (279)

Novel Therapy for Functional Cure of Chronic Hepatitis B Virus Infection

, 2021
Functional cure is the currently preferable and optimal treatment endpoint, which refers to sustained seroclearance of HBsAg with or without seroconversion of antibody to HBsAg. Functional cure is associated with improved clinical outcomes.
Lung-Yi Mak, , Mak Lung-Yi
exaly   +2 more sources

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Pulmonary function in cured pulmonary tuberculosis cases

Indian Journal of Tuberculosis, 2022
In clinical practice it has been observed that several patients of cured pulmonary tuberculosis (PTB) suffer with lung dysfunction and these problems are less documented routinely. Prevalence of these abnormalities remains unknown. Aim of this study is to estimate the lung function abnormality and exercise capacity including diffusion capacity of lung ...
Mohan Bandhu Gupta, Sharad Bagri, Ankur Garg, Devendra Kumar Singh, Prashant Choudhary, Subah Sahni   +5 more
openaire   +2 more sources

Elite controllers as a model of functional cure

Current Opinion in HIV and AIDS, 2011
The limitations of life-long antiretroviral therapies for the HIV infection lead to a novel concept of a functional cure developing innovative therapeutic strategies to generate a long-term remission of HIV replication without treatment. This concept requires an understanding of the mechanisms by which HIV is controlled in conditions of undetectable ...
Brigitte, Autran, Benjamin, Descours, Véronique, Avettand-Fenoel, Christine, Rouzioux   +3 more
openaire   +2 more sources

UV-Cured Functional Coatings

2014
This chapter reviews the use of UV-curing technology for the preparation of multifunctional coatings. It is shown that the UV-curing process can be used as a good technique for the preparation of multifunctional coatings that could find advanced and innovative applications in fields such as automotive gloss-coatings, flooring varnish, scratch-resistant
SANGERMANO, MARCO, ROPPOLO, IGNAZIO, Massimo Messori   +2 more
openaire   +2 more sources

CRISPR as a functional cure for hemoglobinopathies

Ugeskrift for Læger
Severe haemoglobinopathies, including sickle cell disease and β-thalassaemia, represent significant global health burdens. CRISPR technology enables precise genetic editing of haematopoietic stem cells, with current therapies focused on boosting fetal haemoglobin production for a functional cure.
Andreas, Glenthøj, Sarah Birgitte Ingemod Sand, Carlsen, Marianne, Hoffmann, Eva Kannik, Haastrup, Lisbeth Pernille, Andersen, Nina, Toft, Brian Thomas, Kornblit, Jesper Brix, Petersen, Henrik, Hasle, Marianne Rosenkrantz Segelcke, Ifversen   +9 more
openaire   +2 more sources

In Search of a (Functional) Cure

Science Translational Medicine, 2013
HIV-infected adults who are able to control viral replication after therapy have small latent reservoirs in long-living cells.
openaire   +1 more source

Stability of the Functional Cure in Congenital Esotropia

Journal of Pediatric Ophthalmology & Strabismus, 2015
Purpose: To report the stability of the functional cure in a chart review of patients with congenital esotropia. Methods: The charts of 31 patients with congenital esotropia, encountered in 2007–2012 with functional cure, were studied.
openaire   +2 more sources

Middle phalangectomy: A functional and aesthetic cure for macrodactyly

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, 2006
Macrodactyly is a rare congenital anomaly of the extremities. Some treatments such as debulking, epiphysiodesis, stripping or resection of the digital nerve, shortening of the fingers, amputation, and angulation osteotomy have been tried. We describe a patient with a giant digit in the hand, and present middle phalangectomy as a suitable treatment.
Dogan, Ali, Tan, Onder, Uslu, Mustafa, Atik, Bekir, Alpaslan, Suleyman   +4 more
openaire   +4 more sources

Discontinuation of TKI therapy and ‘functional’ cure for CML

Best Practice and Research in Clinical Haematology, 2016
Stopping tyrosine kinase inhibitor (TKI) therapy after achieving a sustained deep molecular response is an emerging treatment goal for patients with chronic myeloid leukaemia in chronic phase (CML-CP). Indeed, the feasibility of stopping TKI therapy has been confirmed in various studies.
exaly   +3 more sources

The curing reactions of ethynyl-functional benzoxazine

Reactive and Functional Polymers, 2006
Abstract The model compounds 3-(3-ethynyl-phenyl)-6-methyl-3,4-dihydro-2H-benzoxazine (EPMB) and 6-methyl-3-phenyl-3,4-dihydro-2H-benzoxazine (PMB) were synthesized and the influence of ethynyl group on the thermal cure reaction of benzoxazine compound was investigated. The bond parameters of benzoxazine ring calculated at the level of B3LYP/6-31G(d)
Jianxiang Huang, Jian Zhang, Fan Wang, Farong Huang, Lei Du   +4 more
openaire   +1 more source