Results 181 to 190 of about 3,338,515 (259)

Condition monitoring and multi-fault classification of hydraulic systems using multivariate functional data analysis. [PDF]

Heliyon
Yildirim C, Franco-Pereira AM, Lillo RE.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

mxfda: a comprehensive toolkit for functional data analysis of single-cell spatial data. [PDF]

Bioinform Adv
Wrobel J, Soupir AC, Hayes MT, Peres LC, Vu T, Leroux A, Fridley BL.   +6 more
europepmc   +1 more source

Human L1 Transposition Dynamics Unraveled with Functional Data Analysis. [PDF]

Mol Biol Evol, 2020
Chen D, Cremona MA, Qi Z, Mitra RD, Chiaromonte F, Makova KD.   +5 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Raw-Data Driven Functional Data Analysis with Multi-Adaptive Functional Neural Networks for Ergonomic Risk Classification Using Facial and Bio-Signal Time-Series Data. [PDF]

Sensors (Basel)
Kim S, Shakeri A, Darabi SS, Kim E, Kim K.   +4 more
europepmc   +1 more source

Understanding spatiotemporal patterns of COVID-19 incidence in Portugal: a functional data analysis from August 2020 to March 2022

, 2023
Ribeiro MC, Azevedo L, Santos AP, Leite PP, Pereira MJ.   +4 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Development of a fluorescence-based assay for RecBCD activity using functional data analysis and design of experiments. [PDF]

RSC Chem Biol
Winnifrith A, Brown SR, Jedryszek P, Grant C, Kay PE, Thomas AM, Bradbury JD, Lanyon-Hogg T.   +7 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source