Results 181 to 190 of about 6,800,650 (283)

Pooling random forest and functional data analysis for biomedical signals supervised classification: Theory and application to electrocardiogram data. [PDF]

Stat Med, 2022
Maturo F, Verde R.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Functional Data Analysis of Hand Rotation for Open Surgical Suturing Skill Assessment. [PDF]

IEEE J Biomed Health Inform
Shayan AM, Hitchcock DB, Singh SP, Gao J, Groff RE, Singapogu RB.   +5 more
europepmc   +1 more source

Linear discriminant analysis for multiple functional data analysis. [PDF]

J Appl Stat, 2021
Gardner-Lubbe S.
europepmc   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Healthcare Expenditure and COVID-19 in Europe: Correlation, Entropy, and Functional Data Analysis-Based Prediction of Hospitalizations and ICU Admissions. [PDF]

Entropy (Basel)
Hęćka P, Ejsmont W, Biernacki M.
europepmc   +1 more source

Integrating functional data analysis with case-based reasoning for hypertension prognosis and diagnosis based on real-world electronic health records. [PDF]

BMC Med Inform Decis Mak, 2022
Qi P, Wang F, Huang Y, Yang X.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Historical precipitation and flood damage in Japan: functional data analysis and evaluation of models. [PDF]

PLoS One
Wakai A, Hijioka Y, Yokozawa M, Watanabe M, Sakurai G.   +4 more
europepmc   +1 more source