Results 161 to 170 of about 12,934,423 (302)

Functional Data Analysis for Predicting Pediatric Failure to Complete Ten Brief Exercise Bouts. [PDF]

IEEE J Biomed Health Inform, 2022
Coronato N, Brown DE, Sharma Y, Bar-Yoseph R, Radom-Aizik S, Cooper DM.   +5 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Insights into Neuromuscular Function in Older Adults from Functional Data Analysis of Time-Dependent Handgrip Strength Curves. [PDF]

Bioengineering (Basel)
Urbano D, Inácio M, Restivo MT.
europepmc   +1 more source

Functional data analysis for longitudinal data with informative observation times. [PDF]

Biometrics, 2023
Weaver C, Xiao L, Lu W.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Beyond Static Assessment: A Proof-of-Concept Evaluation of Functional Data Analysis for Assessing Physiological Responses to High-Intensity Effort. [PDF]

J Funct Morphol Kinesiol
Odriozola A, Tirnauca C, González A, Corbi F, Álvarez-Herms J.   +4 more
europepmc   +1 more source

Functional data analysis of the relationship between electricity consumption and climate change drivers. [PDF]

J Appl Stat, 2023
Elayouty A, Abou-Ali H.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Genomic Anomaly Detection with Functional Data Analysis. [PDF]

Genes (Basel)
Kanjilal R, Campelo Dos Santos AL, Arnab SP, DeGiorgio M, Assis R.   +4 more
europepmc   +1 more source

The dynamics of ideology drift among U.S. Supreme Court justices: A functional data analysis. [PDF]

PLoS One, 2022
Zhou X, Müller HG.
europepmc   +1 more source