Results 51 to 60 of about 3,345,035 (259)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Boosting Functional Regression Models with FDboost

Journal of Statistical Software, 2020
The R add-on package FDboost is a flexible toolbox for the estimation of functional regression models by model-based boosting. It provides the possibility to fit regression models for scalar and functional response with effects of scalar as well as ...
Sarah Brockhaus, David Rügamer, Sonja Greven   +2 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Age- and sex-dependency of thrombin generation parameters in the general Italian population: the Moli-sani study

Frontiers in Cardiovascular Medicine
BackgroundRecent developments have made the thrombin generation (TG) test accessible to the clinical laboratory. Therefore, the clinical interpretation of TG parameters has become of increasing interest, and reference values are required.
Simona Costanzo, Bas de Laat, Bas de Laat, Augusto Di Castelnuovo, Lisa van der Vorm, Amalia De Curtis, Chiara Cerletti, Marisa Ninivaggi, Maria Benedetta Donati, Licia Iacoviello, Licia Iacoviello, Romy de Laat-Kremers, the Moli-sani investigators, Licia Iacoviello, Giovanni de Gaetano, Maria Benedetta Donati, Chiara Cerletti, Marialaura Bonaccio, Americo Bonanni, Simona Costanzo, Amalia De Curtis, Augusto Di Castelnuovo, Alessandro Gialluisi, Francesco Gianfagna, Mariarosaria Persichillo, Teresa Di Prospero, Jos Vermylen, Renzo Pegoraro, Antonio Spagnolo, Deodato Assanelli, Livia Rago, Simona Costanzo, Marco Olivieri, Sabatino Orlandi, Teresa Panzera, Augusto Di Castelnuovo, Marialaura Bonaccio, Simona Costanzo, Simona Esposito, Alessandro Gialluisi, Anwal Ghulam, Francesco Gianfagna, Antonietta Pepe, Emilia Ruggiero, Sukshma Sharma, Amalia De Curtis, Concetta Civitillo, Alisia Cretella, Sara Magnacca, Fabrizia Noro, Mariarosaria Persichillo, Francesca Bracone, Fiorella De Rita, Giuseppe Di Costanzo, Sabrina Franciosa, Martina Morelli, Americo Bonanni, Ospedale A. Cardarelli-Campobasso, Ospedale F. Veneziale-Isernia, Ospedale San Timoteo-Termoli, Ospedale Ss. Rosario-Venafro, Ospedale Vietri-Larino, Ospedale San Francesco Caracciolo-Agnone, Casa di Cura Villa Maria-Campobasso   +63 more
doaj   +1 more source

Detection of Multidecadal Changes in Vegetation Dynamics and Association with Intra-Annual Climate Variability in the Columbia River Basin

Remote Sensing, 2022
Remotely-sensed Leaf Area Index (LAI) is a useful metric for assessing changes in vegetation cover and greeness over time and space. Satellite-derived LAI measurements can be used to assess these intra- and inter-annual vegetation dynamics and how they ...
Andrew B. Whetten, Hannah J. Demler
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Functional data analysis by matrix completion [PDF]

The Annals of Statistics, 2019
To appear in the Annals of ...
Descary, Marie-Hélène, Panaretos, Victor M.   +1 more
openaire   +4 more sources

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source

Functional approach to analysis of daily tax revenues

Lietuvos Matematikos Rinkinys, 2019
We present a functional data analysis approach to modeling and analyzing daily tax revenues. The main features of daily tax revenue we need to extract are some patterns within calendar months which can be used for prediction.
Jovita Gudan, Alfredas Račkauskas
doaj   +1 more source

Smoothing and Differentiation of Kinematic Data Using Functional Data Analysis Approach: An Application of Automatic and Subjective Methods

Applied Sciences, 2020
Smoothing is one of the fundamental procedures in functional data analysis (FDA). The smoothing parameter λ influences data smoothness and fitting, which is governed by selecting automatic methods, namely, cross-validation (CV) and generalized ...
Muhammad Athif Mat Zin, Azmin Sham Rambely, Noratiqah Mohd Ariff, Muhammad Shahimi Ariffin   +3 more
doaj   +1 more source