Results 71 to 80 of about 12,934,423 (302)

Decoding the epigenetics and chromatin loop dynamics of androgen receptor-mediated transcription

Nature Communications
Androgen receptor (AR)-mediated transcription plays a critical role in development and prostate cancer growth. AR drives gene expression by binding to thousands of cis-regulatory elements (CRE) that loop to hundreds of target promoters.
Umut Berkay Altıntaş, Ji-Heui Seo, Claudia Giambartolomei, Dogancan Ozturan, Brad J. Fortunato, Geoffrey M. Nelson, Seth R. Goldman, Karen Adelman, Faraz Hach, Matthew L. Freedman, Nathan A. Lack   +10 more
doaj   +1 more source

Current research on profile monitoring Atuais pesquisas em monitoramento de perfis

Production, 2007
In many applications the quality of a process or product is best characterized and summarized by a functional relationship between a response variable and one or more explanatory variables.
William H. Woodall
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Data Integration in Functional Analysis of MicroRNAs [PDF]

Current Bioinformatics, 2011
The discovery of microRNAs (miRNAs), about a decade ago, has completely changed our understanding of the complexity of gene regulatory networks. It has already been shown that they are abundantly found in many organisms and can regulate hundreds of genes in post-transcriptional level. To elucidate the individual or co-operative effects of miRNAs, it is
Ogul, Hasan, Akkaya, Mahinur S.
openaire   +2 more sources

Principal component analysis for functional data on Riemannian manifolds and spheres [PDF]

Annals of Statistics, 2017
Functional data analysis on nonlinear manifolds has drawn recent interest. Sphere-valued functional data, which are encountered for example as movement trajectories on the surface of the earth, are an important special case.
Xiong-Tao Dai, Hans-Georg Müller
semanticscholar   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Prothrombin conversion accelerates with increasing age in women but not in men: findings from the Moli-sani Cohort Study

Research and Practice in Thrombosis and Haemostasis
Background: The thrombin dynamics method has been used as an add-on analysis method for the thrombin generation test over the past years to study the balance between pro- and anticoagulant pathways.
Amalia De Curtis, Romy de Laat-Kremers, Simona Costanzo, Augusto Di Castelnuovo, Marisa Ninivaggi, Chiara Cerletti, Giovanni de Gaetano, Maria Benedetta Donati, Licia Iacoviello, Bas de Laat, Licia Iacoviello, Giovanni de Gaetano, Maria Benedetta Donati, Chiara Cerletti, Marialaura Bonaccio, Americo Bonanni, Simona Costanzo, Amalia De Curtis, Augusto Di Castelnuovo, Alessandro Gialluisi, Francesco Gianfagna, Mariarosaria Persichillo, Jos Vermylen, Renzo Pegoraro, Antonio G. Spagnolo, Deodato Assanelli, Livia Rago, Simona Costanzo, Sabatino Orlandi, Teresa Panzera, Augusto Di Castelnuovo, Marialaura Bonaccio, Francesca Bracone, Simona Costanzo, Giuseppe Di Costanzo, Simona Esposito, Alessandro Gialluisi, Anwal Ghulam, Francesco Gianfagna, Martina Morelli, Maria Loreto Muñoz Venegas, Antonietta Pepe, Emilia Ruggiero, Amalia De Curtis, Concetta Civitillo, Alisia Cretella, Sara Magnacca, Mariarosaria Persichillo, Francesca Bracone, Giuseppe Di Costanzo, Martina Morelli, Americo Bonanni   +51 more
doaj   +1 more source

Functional Data Analysis for Extreme Data

Indian Journal of Science and Technology, 2016
The performance of extreme data is observed by using functional data analysis with two extreme values theory approaches. Functional data analysis is one of the techniques to represent data in a functional form or as a smooth curve rather than in a discrete form.
Mohamad Adnan, Noor Izyan, Adam, Mohd. Bakri, Ishak, Mohd. Yusoff, Ibrahim, Noor Akma, Azmai, Mohammad Noor Amal   +4 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

On the Christoffel function and classification in data analysis

Comptes Rendus. Mathématique, 2022
We show that the empirical Christoffel function associated with a cloud of finitely many points sampled from a distribution, can provide a simple tool for supervised classification in data analysis, with good generalization properties.
openaire   +4 more sources