Results 91 to 100 of about 6,800,650 (283)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
On the Christoffel function and classification in data analysis
Comptes Rendus. Mathématique, 2022 We show that the empirical Christoffel function associated with a cloud of finitely many points sampled from a distribution, can provide a simple tool for supervised classification in data analysis, with good generalization properties.
openaire +4 more sources
Data Integration in Functional Analysis of MicroRNAs [PDF]
Current Bioinformatics, 2011 The discovery of microRNAs (miRNAs), about a decade ago, has completely changed our understanding of the complexity of gene regulatory networks. It has already been shown that they are abundantly found in many organisms and can regulate hundreds of genes in post-transcriptional level. To elucidate the individual or co-operative effects of miRNAs, it is
Ogul, Hasan, Akkaya, Mahinur S.
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Experimental Investigation on the Elicitation of Subjective Distributions
Frontiers in Psychology, 2019 Elicitation methods aim to build participants' distributions about a parameter of interest. In most elicitation studies this parameter is rarely known in advance and hinders an objective comparison between elicitation methods.
Carlos J. Barrera-Causil +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frontiers in MicrobiologyA novel machine learning-assisted approach for formula optimization, termed UD-SVR, is introduced by combining uniform design with support vector regression.
Yu-han Li +13 more
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Frontiers in Human Neuroscience, 2019 Functional near-infrared spectroscopy (fNIRS) research articles show a large heterogeneity in the analysis approaches and pre-processing procedures. Additionally, there is often a lack of a complete description of the methods applied, necessary for study
Paola Pinti +5 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Application of Functional Data Analysis in Complex Human Movement Analysis
Quality in SportFunctional data analysis, pioneered by Ramsay, the president of the statistical society of Canada, is a novel statistical method widely applied in the field of human movement analysis.
Baifa Zhang, Zhi-Cheng Lin
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